Celiac Disease and Paraproteinemia (Serum Monoclonal Proteins)

Found this interesting as an iridiology picture indicates that I am not digesting protein and that cells are surrounded by something and protein at least is not getting into cells. I also have a blob of something on one eye which seems to be causing changing readings from 20/25 - 20/60. Can this have to do with celiac disease which I have?

Hello.

I receive the email updates. I found a lot of information in this article I did not understand, but with a bit of studying have made sense of it. Thank you for including it on your site.

Very interesting article. My mother has MGUS and recently I have begun to suspect she (and I) have gluten sensitivity based on other symptoms. This article adds more support to my efforts to get her to stay on a gluten-free diet.

This theory definitely sounds logical to me. I am a newly diagnosed Celiac who suspects there are many more celiacs in my large family. Specifically, I have an aunt who died of Multiple Myeloma and cousins with IBS. There is so much more to be learned about Celiac and autoimmune diseases.

I am a dermatitis herpetiformis and coeliac disease patient and I have had raised levels of gamma kappa paraproteins for some years now. I have a blood test about every 6 months and thankfully, nothing untoward has occurred. I have been on a strict gluten-free diet for the last 8 years but these paraproteins don't disappear. The doctors just tell me they are non-specific.

Wonderful, but scary news. It is nice to see some research going on about celiac and cancer.

Interesting enough to email to my doctor...

This is a very interesting article. I often search for genetic links, or th 'why I have celiac'. My father died of Leukemia at age 38. I was diagnosed with celiac at age 30, with osteoporosis at age 36. Now at 51 my osteoporosis is reversed, I'm healthy and enjoying life and FOOD. But I will be checked for MGUS.

Interesting article. I was diagnosed with celiac disease about 2 1/2 years ago, and with MGUS (IgG kappa) shortly after that. At that time, my endocrinologist (I'm osteoporotic) attributed the MGUS to the celiac. As to the disappearance of the paraprotein, my paraprotein levels have remained stable over the 2 1/2 years.

Very interesting. My father was diagnosed with MGUS approx 10 years ago and I was finally diagnosed with celiac disease 6/07 after having symptoms since childhood. Ironically, both of my parents were tested for celiac after my confirmed diagnosis and both their tissue antibodies came back negative. Definitely warrants some investigation.

I am a 55 year old woman who was diagnosed with MGUS by Dr. Durie at Cedar's Sinai Medical Center in 1995. My IGg numbers have been pretty constant since. When I went for my first colonoscopy screening last month I happened to mention to the doctor that I occasionally had bouts of IBS. He tested me for celiac disease but the results were neg. He did mention that because my IGa was low it might cause a false reading. Since I did not want to have any invasive procedures done I decided to try a gluten free diet. There has been a noticeable absence of intestinal pain. I was already anticipating my upcoming MGUS lab work in May, thinking there may be some correlation when I read this article. I would like to get in touch with the author of this article to update you further and compare notes. Thank you so much for validating my suspicions.

The info is interesting. However, I would temper the advice that every celiac get the MGUS testing. If there is nothing that medicine knows to do, why get the testing? It will only provide another medical record and 'diagnosis' used against the person when he or she seeks health insurance. Stay on a gluten-free diet and undertake other health-oriented nutritional therapy. I frankly don't believe that the diagnostic system used in conventional medicine is helpful in our quest to understand whole body dynamics.