Jump to content
This site uses cookies. Continued use is acceptance of our Terms of Use and Privacy Policy. More Info... ×
  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.




  • Celiac.com Sponsor (A1):



    Celiac.com Sponsor (A1-M):


  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate
  • Record is Archived

    This article is now archived and is closed to further replies.

    Jefferson Adams
    Jefferson Adams

    People with Celiac Disease Face Higher Risk of Psoriasis

    Reviewed and edited by a celiac disease expert.
    People with Celiac Disease Face Higher Risk of Psoriasis - Photo: CC - mysiana
    Caption: Photo: CC - mysiana

    Celiac.com 05/19/2012 - Because a number of past studies examining the connection between celiac disease and psoriasis have had contradictory findings, researchers wanted to get a better idea of the actual risk of psoriasis in patients with biopsy-verified celiac disease.

    Photo: CC - mysianaThe researchers were J.F. Ludvigsson, B. Lindelöf, F. Zingone, and C. Ciacci, with the Department of Pediatrics at Sweden's Örebro University Hospital.

    Celiac.com Sponsor (A12):
    For their study, they used data from 28 pathology departments in Sweden to identified individuals with celiac disease diagnosed between 1969 and 2008. They found 28,958 patients with Marsh 3 villous atrophy.

    They then used Cox regression to compare those celiac disease patients with 143,910 sex- and age-matched control subjects, and to assess the risk of psoriasis.

    They found that celiac disease was a risk factor for future psoriasis (hazard ratio (HR) = 1.72; 95% confidence interval (CI) = 1.54-1.92. They found that, during follow-up, 401 individuals with celiac disease and 1,139 controls were diagnosed with psoriasis.

    They found that the absolute risk of future psoriasis in patients with celiac disease was 135 per 100,000 person-years, with an excess risk of 57 cases per 100,000 person years.

    Overall, 42% of the cases of psoriasis in patients with celiac disease could be attributed to celiac disease. Moreover, in children the team saw a strong association between celiac disease and psoriasis (HR = 2.05; 95% CI = 1.62-2.60).

    Their results show that the connection between celiac disease and psoriasis seems to be far more than coincidental, as we also found a positive association between celiac disease and psoriasis before celiac diagnosis, with an odds ratio of 1.91; 95% CI = 1.58-2.31).

    They conclude that individuals with celiac disease do, in fact, face an increased risk of psoriasis both before and after celiac diagnosis.

    Source:

    • Open Original Shared Link.


    User Feedback

    Recommended Comments

    Guest Stu

    Not exactly news to me. From the age of 5 until my mid-50s I suffered from several large patches of plaque psoriasis on my major joints, the palms of my hands, and the soles of my feet which would often crack open and bleed. I had been to several doctors about it, but none of their treatments brought any relief, and a few made it even worse, leading to secondary skin lesions and infections. Within a week of going gluten-free, the patches began to fade, and within a few months, only a tiny dime-sized patch remained on my right knee. Today, within hours of accidental gluten exposure, dry white blisters form on the palms of my hands and the skin takes several weeks to dry, crack, and eventually sluff-off. Curiously, none of my doctors seem to think this is a significant indicator of gluten intolerance. I'm glad to see the world is finally beginning to notice.

    Link to comment
    Share on other sites
    Guest Sarah S

    Posted

    My sister is 33 and recently found out she has celiac disease. She has suffered from severe psoriasis since she was 9. We had always attributed it to stress. It makes sense that it would have actually come from her celiac disease though. Her gluten-free diet is helping.

    Link to comment
    Share on other sites
    Guest Jen

    My eczema/psoriasis improved dramatically after going on a gluten-free diet. I always thought it was a coincidence. Very interesting that it is not. Since I don't have typical gastrointestinal symptoms for my Celiac, just vitamin deficiencies, I will watch the psoriasis symptoms as a guide for when I've accidentally eaten something with gluten.

    Link to comment
    Share on other sites
    Guest Joan

    As an undiagnosed celiac in December, 1995, I scratched my knee which led to a variety of nasty skin rashes, one of which was diagnosed as psoriasis. I had colon cancer in March, 1996. Since it was not dermatitis herpepiformis, local celiac disease goop and doctors said it was not celiac disease related. I was sure that it was.

    Link to comment
    Share on other sites
    Guest Maria

    Posted

    As an undiagnosed celiac in December, 1995, I scratched my knee which led to a variety of nasty skin rashes, one of which was diagnosed as psoriasis. I had colon cancer in March, 1996. Since it was not dermatitis herpepiformis, local celiac disease goop and doctors said it was not celiac disease related. I was sure that it was.

    I also had weird rashes. I would be in the shower and get a burning sensation on my leg. When I dried off it would stop burning and the next day it looked like prickly heat and it would come back in the shower at times in the same spot. I suffered from reflux for years, developed Graves disease (thyroid), osteoporosis, my gall bladder stopped working and 3 years after it was removed I got stomach bloating and extreme gas and foul bowels. I got a new gastroenterologist that did all blood work for celiac diseaes, hydrogen breath tests for parasites and food intolerances. I had an endoscopy and colonoscopy. All showed nothing, except I had one gene positive for celiac diseaes and one negative. I cannot have any dairy, soy or gluten based on my own body's feeling sick when I do. The rashes have gone, and for the most part I feel better, though I am still tired at times. Celiac diagnosis is very hard to get unless you have the flattened villi or the blistery rash or both genes positive. There still may be other genes they are unaware of though. You must be your own doctor.

    Link to comment
    Share on other sites
    Guest Bill

    Interesting. I have had psoriasis for 50 years, and not one doctor has ever related it to celiac disease, yet my symptoms for celiac seem to match what I'm reading in this report. I will try a gluten-free diet for 2 weeks to pinpoint a problem with food, celiac and psoriasis. Then I will see my doctor.

    Link to comment
    Share on other sites


    Guest
    This is now closed for further comments

  • Get Celiac.com Updates:
    Support Celiac.com:
    Donate
  • About Me

    Jefferson Adams

    Jefferson Adams is Celiac.com's senior writer and Digital Content Director. He earned his B.A. and M.F.A. at Arizona State University. His articles, essays, poems, stories and book reviews have appeared in numerous magazines, journals, and websites, including North American Project, Antioch Review, Caliban, Mississippi Review, Slate, and more. He is the author of more than 2,500 articles on celiac disease. His university coursework includes studies in science, scientific methodology, biology, anatomy, physiology, medicine, logic, and advanced research. He previously devised health and medical content for Colgate, Dove, Pfizer, Sharecare, Walgreens, and more. Jefferson has spoken about celiac disease to the media, including an appearance on the KQED radio show Forum, and is the editor of numerous books, including "Cereal Killers" by Scott Adams and Ron Hoggan, Ed.D.

    >VIEW ALL ARTICLES BY JEFFERSON ADAMS

     


  • Celiac.com Sponsor (A17):
    Celiac.com Sponsor (A17):





    Celiac.com Sponsors (A17-M):




  • Related Articles

    Scott Adams
    Br J Dermatol. 2004 Oct;151(4):891-4
    Celiac.com 11/09/2004 – A study carried out by Irish researchers to determine whether there is an association between celiac disease antibodies and psoriasis activity found that the presence of Antigliadin antibodies (AGA) did increase the severity of the disease. The researchers looked at 130 patients with psoriasis and screened them for serum IgG and IgA AGA, IgA antitransglutaminase and IgA antiendomysial antibodies. The patients were invited to undertake an endoscopy with duodenal biopsy. They found that a significantly higher proportion of psoriasis patients had elevated celiac disease associated antibody levels, and those with elevated antibodies had previously required systemic immunosuppressants or psoralen plus ultraviolet A phototherapy. ...


  • Recent Activity

    1. - Kathleen JJ replied to Kathleen JJ's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
      3

      Options - 7 year old boy - Helicobacter pylori and serology

    2. - StaciField replied to StaciField's topic in Related Issues & Disorders
      6

      My bone structure is disintegrating and I’m having to have my teeth removed

    3. - Kathleen JJ replied to Kathleen JJ's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
      3

      Options - 7 year old boy - Helicobacter pylori and serology

    4. - cristiana replied to Kathleen JJ's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
      3

      Options - 7 year old boy - Helicobacter pylori and serology

    5. - Kathleen JJ posted a topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
      3

      Options - 7 year old boy - Helicobacter pylori and serology


  • Celiac.com Sponsor (A19):



  • Member Statistics

    • Total Members
      126,055
    • Most Online (within 30 mins)
      7,748

    malcolmg
    Newest Member
    malcolmg
    Joined

  • Celiac.com Sponsor (A20):


  • Forum Statistics

    • Total Topics
      120.9k
    • Total Posts
      69.1k

  • Celiac.com Sponsor (A22):





  • Celiac.com Sponsor (A21):



  • Popular Now

    • Captain173
      10
    • jjiillee
      5
    • Kristina12
      7
    • StaciField
    • ShRa
      9
  • Popular Articles

    • Scott Adams
    • Scott Adams
    • Scott Adams
    • Scott Adams
    • Scott Adams
  • Upcoming Events

×
×
  • Create New...