Pete Dixon

https://doi.org/10.1093/ibd/izad110 

Celiac.com Sponsor (A13):
Published June 15, 2023 in the journal of Inflammatory Bowel Diseases, this study is expressly for ulcerative colitis, but because the focus was on safety and tolerance of hookworms as a treatment, the results should apply for any of the myriad conditions people use hookworms to treat. It's a pilot study paving the way for future full-scale randomized controlled trials regarding efficacy.

The study used 30 Necator americanus larvae. The self-treating community has moved away from the practice of using such a large initial larvae number because of the tendency to create a phenomenon we call worm flu, so what discomfort the study participants experienced would be expected to be less when treating in a home setting.

I think it's great this level of research is being carried out. It's a sign of real interest in proving out the results the community of helminth self-treaters see in their daily lives. For now though what have presented here is evidence that using hookworms is practical (feasible, safe, and well-tolerated), and that's a good start.