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  • Jefferson Adams
    Jefferson Adams

    A New Study Looks at the Long-Term Effects of a Gluten-Free Diet on Women with Celiac Disease

    Reviewed and edited by a celiac disease expert.

    A new study looks at the long-term nutritional and health impact of a long-term gluten-free diet on Saudi women with celiac disease.

    A New Study Looks at the Long-Term Effects of a Gluten-Free Diet on Women with Celiac Disease - Image: CC BY-SA 2.0--Thomas Berg
    Caption: Image: CC BY-SA 2.0--Thomas Berg

    Celiac.com 12/07/2022 - What is the nutritional and health impact of a long-term gluten-free diet on people with celiac disease? A team of researchers recently set out to take a deep look at the influence of a long-term gluten-free diet on nutritional status, body composition, and associated factors in adult Saudi females with celiac diseases. 

    One Year Study of Fifty-one Diagnosed Celiac Patients

    For their study, the team included fifty-one diagnosed celiac patients who had followed a gluten-free diet for over one year.  They collected data on patient dietary patterns, along with a complete analysis of anthropometric parameters, levels of vitamins B12 and D, and complete blood count (CBC). 

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    The data show that all patients suffered from an insufficient intake of all micro and macro-nutrients, including vitamin D, folate, calcium, and iron. Otherwise, their bloodwork fell within the expected ranges. 

    While one-third of patients were slim, nearly half showed decreased total body fat, more than half of the patients showed low waist/hip ratios, and more than sixty-percent showed decreased levels of visceral fat. On the whole, patients with poor nutritional status also tended to have poor educational levels and some psychosocial factors that may have influenced their results.

    However, the team did find that a gluten-free diet in women with celiac disease negatively affects their nutritional intake and anthropometric indices, and leads to a deficiency in major nutrients, vitamins, and ions.

    Study Conclusions

    This study confirms other studies that show that gluten-free foods often have poorer nutritional quality than their non-gluten-free counterparts, and that many people with celiac disease suffer from poor nutrition or malnutrition. 

    The results highlight the need for women, but also for all celiacs on a gluten-free diet, to be extra vigilant about making sure to get enough nutrition, fiber and nutrients.

    Nutrients 2022, 14(10), 2090

     

    The research team included Aeshah Ibrahim Alhosain, Ghedeir M. Alshammari, Barakat Lafi Almoteri, Mohammed A. Mohammed, Manal Abdulaziz Binobead, and Mohammed Abdo Yahya. They are variously affiliated with theDepartment of Food Science and Nutrition, College of Food and Agricultural Sciences, King Saud University in Riyadh, Saudi Arabia, and the Department of Gastroenterology, Buraidah Central Hospital, Ministry of Health in Buraydah, Saudi Arabia.


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    Guest Note

    Note- this is a study of 51 patients 

     

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    Scott Adams

    Yes, as mentioned in the very first sentence! 😉

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    Guest Vintagesilver

    Posted

    Good to know that research is ongoing and celiac is being recognized around the world . All 51 had macro and micro nutrient deficent gets your attention , thanks for bringing this article to us all . 

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    trents

    I wonder if this study group included those who were supplementing?

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    Flash1970

    I think this is a very strange study.  What was their diet?  Are they allowed to choose their own food?  Nothing is mentioned.  A gluten free diet can include empty foods like all processed food.  Rice,  corn,  e.t.c.  I don't think you can conclude anything from this poor study.  People should not make assumptions based on this study.  Everyone is different and everyone  has different diets. If you're eating a varied diet including meat,  vegetables,  fruit, then you're probably not deficient.  I think it's a good idea for everyone to have their blood tested and then decide what to do.  Do not make a decision because of this study.  

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    trents

    I agree. It is a strange study. I still find it hard to believe that people who eliminate wheat from their diet are going to be really challenged in compensating the nutritional loss associated with enriched flour. That is, unless wheat products were the main part of their diet to begin with. I possibly can see it in third world settings but not otherwise. There are just too many other foods available to most people that possess those same nutrients.

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    poppy2017

    This study seems very flawed.

    The sample size is too small.

    One year is hardly "long term."

    Were nutrient levels measured before the study?

    What sort of foods did these women have access to?

    This really demonstrates how even peer-reviewed reports can not be taken at face value.

    Thank you for sharing.

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    Posterboy

    To All,

    There is this study by the Mayo Clinic....a couple years ago.

    Entitled "Micronutrient Deficiencies Are Common in Contemporary Celiac Disease Despite Lack of Overt Malabsorption Symptoms"

    I wrote a blog post about it might help anyone who is following this article.

    There is this study from Australia that is approx. 10 years old that shows Thiamine status goes down while on a gluten free diet......

    Enitled "Nutritional inadequacies of the gluten-free diet in both recently-diagnosed and long-term patients with coeliac disease" and I would subtitle "A case for Thiamine Supplementation in Celiacs"

    https://pubmed.ncbi.nlm.nih.gov/23198728/

    And this could explain the "Thin Villi" that Celiacs get....

    In part, this triggered me to write this Posterboy blog post explaining why all Celiac's should supplement with Thiamine for at least "Season in Time" and IF I had to write it again.....I would of entitled it.....why all Celiac's should supplement with a B-Complex for a "Season in Time"

    I hope this is helpful but it is not medical advice.

    Posterboy by the grace of God,

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    Wheatwacked

    "This finding is consistent with the Segura and Rosell [23] who reported that commercial GFD products often have the least nutritional value compared to gluten-rich ones." 

    I think this is the key phrase in that report. Long-Term Effect of Gluten-Free Diets on Nutritional Status, Body Composition, and Associated Factors in Adult Saudi Females with Celiac Disease

    Facsimile gluten foods made with gluten free ingredients are not fortified as are their gluten counterparts. 

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  • About Me

    Jefferson Adams

    Jefferson Adams is Celiac.com's senior writer and Digital Content Director. He earned his B.A. and M.F.A. at Arizona State University. His articles, essays, poems, stories and book reviews have appeared in numerous magazines, journals, and websites, including North American Project, Antioch Review, Caliban, Mississippi Review, Slate, and more. He is the author of more than 2,500 articles on celiac disease. His university coursework includes studies in science, scientific methodology, biology, anatomy, physiology, medicine, logic, and advanced research. He previously devised health and medical content for Colgate, Dove, Pfizer, Sharecare, Walgreens, and more. Jefferson has spoken about celiac disease to the media, including an appearance on the KQED radio show Forum, and is the editor of numerous books, including "Cereal Killers" by Scott Adams and Ron Hoggan, Ed.D.

    >VIEW ALL ARTICLES BY JEFFERSON ADAMS

     


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