Jump to content
This site uses cookies. Continued use is acceptance of our Terms of Use and Privacy Policy. More Info... ×
  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.




  • Celiac.com Sponsor (A1):



    Celiac.com Sponsor (A1-M):


  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate
  • Record is Archived

    This article is now archived and is closed to further replies.

    Jefferson Adams
    Jefferson Adams

    Autoimmune Thyroid Disease Carries Greater Prevalence and Relative Risk of Other Autoimmune Diseases

    Reviewed and edited by a celiac disease expert.

    Celiac.com 03/01/2010 - Common autoimmune disorders often coexist in the same subjects, and to cluster in families. A research team recently set out to quantify the risk of diagnosis of coexisting autoimmune diseases in more than 3000 index cases with clinically proven Graves' disease or Hashimoto's thyroiditis.

    The research team included Kristien Boelaert, PhD, Paul R. Newbya, Matthew J. Simmonds, PhD, Roger L. Holder, Jacqueline D. Carr-Smith, Joanne M. Heward, PhD, Nilusha Manjia, Amit Allahabadia, MD, Mary Armitage, DM, Krishna V. Chatterjee, PhD, John H. Lazarus, MD, Simon H. Pearce, PhD, Bijay Vaidya, PhD, Stephen C. Gough, PhD, and Jayne A. Franklyn, PhD.

    Celiac.com Sponsor (A12):
    To establish the prevalence of coexisting autoimmune disorders, the team conducted a cross-sectional multi-center study of 3286 Caucasian subjects from UK hospital thyroid clinics. 2791 of those had Graves' disease, 495 had Hashimoto's thyroiditis.

    The team used a comprehensive questionnaire to obtain complete personal and parental history for each subject, including information on common autoimmune disorders, and parental history of hyperthyroidism or hypothyroidism.

    The frequency of other autoimmune disorders was 9.67% for patients with Graves' disease and 14.3% for those with Hashimoto's thyroiditis index cases (P=.005).

    Rheumatoid arthritis was the most common coexisting autoimmune disorder, striking 3.15% of patients with Graves' disease, and 4.24% of Hashimoto's thyroiditis cases.

    However, both conditions carried substantially higher relative risks for nearly all other autoimmune diseases (>10 for pernicious anemia, systemic lupus erythematosus, Addison's disease, celiac disease, and vitiligo).

    Cases of Graves' disease showed relative “clustering” among index subjects with parental hyperthyroidism, while cases of Hashimoto's thyroiditis showed relative “clustering” among index subjects with parental hypothyroidism.

    Relative risks for most other coexisting autoimmune disorders were markedly increased among parents of index cases.

    This study is one of the largest so far to quantify the risk of diagnosis of coexisting autoimmune diseases among more than 3000 index cases with clinically proven Graves' disease or Hashimoto's thyroiditis.

    These results emphasize the the importance of screening for other autoimmune diagnoses when patients with autoimmune thyroid disease show new or nonspecific symptoms.

    Source:
    Open Original Shared Link




    User Feedback

    Recommended Comments

    Guest bessahraoui

    Posted

    This is a good article.

    Link to comment
    Share on other sites
    Guest Joanne

    Posted

    Being newly diagnosed with Hashimoto's Thyroiditis, I'm reading everything I can get my hands on. My Naturopath explained how gluten intolerance plays a big part in the disease. I've been gluten-free for almost 1 week and already see an improvement in my symptoms. Still waiting on blood test results to confirm the severity. Very happy to see that more people are realizing the dangers of wheat products andgGluten.

    Link to comment
    Share on other sites


    Guest
    This is now closed for further comments

  • Get Celiac.com Updates:
    Support Celiac.com:
    Donate
  • About Me

    Jefferson Adams

    Jefferson Adams is Celiac.com's senior writer and Digital Content Director. He earned his B.A. and M.F.A. at Arizona State University. His articles, essays, poems, stories and book reviews have appeared in numerous magazines, journals, and websites, including North American Project, Antioch Review, Caliban, Mississippi Review, Slate, and more. He is the author of more than 2,500 articles on celiac disease. His university coursework includes studies in science, scientific methodology, biology, anatomy, physiology, medicine, logic, and advanced research. He previously devised health and medical content for Colgate, Dove, Pfizer, Sharecare, Walgreens, and more. Jefferson has spoken about celiac disease to the media, including an appearance on the KQED radio show Forum, and is the editor of numerous books, including "Cereal Killers" by Scott Adams and Ron Hoggan, Ed.D.

    >VIEW ALL ARTICLES BY JEFFERSON ADAMS

     


  • Celiac.com Sponsor (A17):
    Celiac.com Sponsor (A17):





    Celiac.com Sponsors (A17-M):




  • Related Articles

    Scott Adams
    AUTHORS: Cuoco L; Certo M; Jorizzo RA; De Vitis I; Tursi A; Papa A; De Marinis L; Fedeli P; Fedeli G; Gasbarrini G
    AUTHOR AFFILIATION: Department of Internal Medicine, Catholic University S.C., Rome, Italy.
    SOURCE: Ital J Gastroenterol Hepatol 1999 May;31(4):283-7 [MEDLINE record in process]
    CITATION IDS: PMID: 10425571 UI: 99354303
    ABSTRACT: BACKGROUND AND AIMS - Celiac disease is associated with several autoimmune disorders such as insulin-dependent diabetes, Sjogrens syndrome, Addisons disease and thyroid diseases. The aim of our study was to evaluate the prevalence of celiac disease in patients affected by autoimmune thyroid diseases by means of anti-gliadin and anti-endomysial antibodies. PATIENTS: We studied 92 patients affected by autoimmune thyroid diseases...


    Jefferson Adams
    Celiac.com 11/25/2008 - Celiac disease is one of the most under-diagnosed medical disorders, with 97% of all cases currently remaining undiagnosed. According to the National Institutes of Health, 3 million people in theUnited States with celiac disease, while only 140,000 have beendiagnosed. Celiac disease ismore than twice as common in people over 50 years of age.
    People with untreated celiac disease are at risk of developing anynumber of associated conditions, including gastrointestinal cancer atrates of 40 to 100 times those of the general population, in additionto osteoporosis, and a two-fold increase in the risk of fractures,including first-time hip fractures. Moreover, an unusually highpercentage of people with celiac disease suffer from the followingconditions: Anemia, Arthritis...


    Jefferson Adams
    Celiac.com 02/10/2010 - A team of researchers recently set out to determine whether patients with autoimmune thyroid disease risk developing secondary autoimmune disorders, and whether such diseases tend to cluster in families.
    The research team included Kristien Boelaert, PhD, Paul R. Newbya, Matthew J. Simmonds, PhD, Roger L. Holderb, Jacqueline D. Carr-Smitha, Joanne M. Heward, PhD, Nilusha Manjia, Amit Allahabadia, MD, Mary Armitage, DM, Krishna V. Chatterjee, PhD, John H. Lazarus, MD, Simon H. Pearce, PhD, Bijay Vaidya, PhD, Stephen C. Gough, PhD, Jayne A. Franklyn, PhD.
    To properly assess the prevalence of coexisting autoimmune disorders, the team conducted a cross-sectional multi-center study of 3286 Caucasian patients at UK hospital thyroid clinics. 2791 of the patients had...


    Jefferson Adams
    Celiac.com 02/02/2012 - A team of researchers recently conducted a prospective controlled study on a gluten-free diet and autoimmune thyroiditis in patients with celiac disease.
    The research team included S. Metso, H. Hyytiä-Ilmonen, K. Kaukinen, H. Huhtala, P. Jaatinen, J. Salmi, J. Taurio, and P. Collin. They are affiliated with the Department of Internal Medicine at Tampere University Hospital in Tampere, Finland.
    Prior to the study, there had been contradictory data regarding the ways in which early diagnosis and a gluten-free diet might slow the progression of associated autoimmune diseases in celiac disease.
    The research team investigated the course of autoimmune thyroid diseases in newly diagnosed celiac disease patients, both before and after gluten-free dietary treatment....


  • Recent Activity

    1. - knitty kitty replied to CeliacChica's topic in Related Issues & Disorders
      30

      Muscle Twitching

    2. - Jtestani posted a topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
      0

      Help with results please. As I have a appt after the New Year.

    3. - StaciField replied to StaciField's topic in Related Issues & Disorders
      8

      My bone structure is disintegrating and I’m having to have my teeth removed

    4. - Wheatwacked replied to More2Learn's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
      2

      Celiac Maybe a Possibility?

    5. - John.B posted a topic in Gluten-Free Foods, Products, Shopping & Medications
      0

      Allergy Meds


  • Celiac.com Sponsor (A19):



  • Member Statistics

    • Total Members
      126,136
    • Most Online (within 30 mins)
      7,748

    kfkynett
    Newest Member
    kfkynett
    Joined

  • Celiac.com Sponsor (A20):


  • Forum Statistics

    • Total Topics
      120.9k
    • Total Posts
      69.2k

  • Celiac.com Sponsor (A22):





  • Celiac.com Sponsor (A21):



  • Popular Now

    • Vozzyv
      5
    • Kathleen JJ
    • Cindy Neshe
  • Popular Articles

    • Scott Adams
    • Scott Adams
    • Scott Adams
    • Scott Adams
    • Scott Adams
  • Upcoming Events

×
×
  • Create New...