Could Changing Gut Bacteria Prevent Celiac Disease?

Reading the linked article reveals this discouraging assertion:

"Its results won't help those who already have celiac disease."

This is exciting research!

This is an interesting subject as I have already seen how certain gut bacteria can either greatly benefit or greatly slow peristalsis through either allowing tryptophan to be absorbed and converted into serotonin or instead cause malabsorption and breakdown of tryptophan. So proper enteric bacterial population is very important and I have found only one really great source which is Wallaby Kefir which contains several serotogenic varieties.

On another subject I define Celiac patients as poor digesters of protein. Therefore, achlorhydria (a lack of stomach acid) couild indeed be the first domino in the ultimate indigestion of the gliaden protein , and a stomach with a low pH keeps other bacterial interlopers that do not belong from invading the intestine, a very important function, plus stomach acid enables Pepsin activation, the first step in complex protein breakdown of gliaden, and that acidity initiates brush border and pancreatic enzymes such as prolyl endopeptidase to further cleave the Gliadin protein that initiates Celiac response.

I think this bacterial role is a valid point. There are symbiotic bacteria in the human gut which must be encouraged, while the bad dysbiotic bacteria need to be prevented such as those found in Small Intestinal bacterial overgrowth, and the stomach acid and later basic bicarbonate and digestive enzymes from the pancreas also plays an important role in segregating those bacteria......thanks

Fascinating. I technically don't have celiac disease. I had a positive blood test, but negative biopsy. However, in college , I had a terrible time with repeated bouts of strep throat and sinusitis, and took numerous courses of antibiotics. I now wonder if that changed my gut bacteria and started me down the road of gluten intolerance.

My son was hospitalized for a week and was on constant IV antibiotics during that time. About 8 months after he was discharged I was concerned that he was not gaining weight. Blood work and endoscopy w/biopsy confirmed celiac disease. My son is 17 years old, 6' 3 1/2" and weighs 145 lbs. I believe the week of constant IV antibiotics triggered his celiac disease.