Celiac Disease Masquerades as Extreme Thrombocytosis and Severe Anemia in a 52-Year-Old Female Patient

On 8/15/2023 at 7:05 PM, knitty kitty said:

Be aware blood levels do not accurately reflect the level of vitamins being stored and utilized inside cells and tissues.  The vitamins inside cells can be depleted while blood levels show "normal" levels.  These are confiscated to keep the brain and heart supplied, while other organs do without.

Blood levels can reflect how much of the vitamin you've consumed in the previous day or two.  

Do Not start supplementing before you have your blood drawn for your vitamin assay.  Supplementing before testing will reflect the supplements ingested.

After testing and talking to your doctor, supplement with B Complex vitamins and look for health improvement.  If not needed, water soluble B vitamins are easily excreted in urine.  

Best wishes.

Thank you so much for the heads up on this issue.  Makes great sense.

On 8/16/2023 at 10:29 AM, Wheatwacked said:

What do you consider large dose.  I am 72 and have to take 10,000 IU a day to maintain 80 ng/ml (200 nmol/L).  

       Mayo Clinic Proceedings: Vitamin D Is Not as Toxic as Was Once Thought   "The evidence is clear that vitamin D toxicity is one of the rarest medical conditions... Ekwaru et al16 recently reported on more than 17,000 healthy adult volunteers participating in a preventative health program and taking varying doses of vitamin D up to 20,000 IU/d. These patients did not demonstrate any toxicity, and the blood level of 25(OH)D in those taking even 20,000 IU/d was less than 100 ng/mL"

Really very valuable info.  I have not heard this before and will further investigate.  Thank you.

On 8/15/2023 at 11:00 AM, trents said:

"The patient showed no gastrointestinal symptoms, and had no family history of gastroenterological diseases."

Highlights the reality of "silent" celiac disease which most doctors don't have a concept for but is very common in the celiac population.

So true and a problem to be addressed in the near future  I hope.  

On 8/15/2023 at 11:54 AM, knitty kitty said:

@Phyllis Stempinski, Welcome to the forum!

Yes, do follow up with your internist and nutritionist.  Checking for nutritional deficiencies is part of proper follow up care for Celiac people.  

It's unusual to be deficient in just one vitamin.   Usually Celiacs have poor absorption of the eight essential B vitamins and minerals like magnesium and zinc which all help with anemia.  

Best wishes.

Thank you.  Will do

On 8/16/2023 at 10:29 AM, Wheatwacked said:

What do you consider large dose.  I am 72 and have to take 10,000 IU a day to maintain 80 ng/ml (200 nmol/L).  

       Mayo Clinic Proceedings: Vitamin D Is Not as Toxic as Was Once Thought   "The evidence is clear that vitamin D toxicity is one of the rarest medical conditions... Ekwaru et al16 recently reported on more than 17,000 healthy adult volunteers participating in a preventative health program and taking varying doses of vitamin D up to 20,000 IU/d. These patients did not demonstrate any toxicity, and the blood level of 25(OH)D in those taking even 20,000 IU/d was less than 100 ng/mL"

Great info to discuss with new gastroenterologist.  I was not aware of this study/info.  I thought my 5,000 units per day was the max.  Old info at this point.  Thank you so much.