Celiac Disease Patients Show Higher Rates of Psychiatric Disorders

Maybe the psych disorders are sequelae from years and years of enduring every gastro test under the sun before being (blessedly, finally) DXed with something so simply fixed as Celiac Disease. I cannot tell you how many horrid tests I endured before diagnosis... And EVEN AFTER diagnosis because the Doc wouldn't believe the diagnosis! 

Wondering if this observation applies to other autoimmune diseases? neuroinflammation is common for all autoimmune diseases and mental disorders mentioned in the study above.

Maybe a subset of these psychiatric disorders are autoimmune themselves. I received my COVID-19 vaccine recently. After the second dose, my immune system seemed to be activated with the expected side effects of malaise and fatigue. However, I also noticed that I felt very sad (a deep emptiness that I have never experienced before) for a day or so. That made me wonder about the connection between immune system activation and depression.

1 hour ago, Guest Celiac dx 2002 said:

Maybe a subset of these psychiatric disorders are autoimmune themselves. I received my COVID-19 vaccine recently. After the second dose, my immune system seemed to be activated with the expected side effects of malaise and fatigue. However, I also noticed that I felt very sad (a deep emptiness that I have never experienced before) for a day or so. That made me wonder about the connection between immune system activation and depression.

An interesting hypotheses indeed. Haven't seen any research to that effect but all knowledge has a starting point.

High levels of histamine have been found in the brains of people with psychiatric disorders.  

High histamine and mast cell activation syndrome has been found in Celiac Disease.

Vitamin and nutritional deficiencies have effects on the brain.

Bread and Other Edible Agents of Mental Disease

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Histamine in neurotransmission and brain diseases

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Vitamin Supplementation in the Treatment of Schizophrenia

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3 hours ago, Guest Celiac dx 2002 said:

Maybe a subset of these psychiatric disorders are autoimmune themselves. I received my COVID-19 vaccine recently. After the second dose, my immune system seemed to be activated with the expected side effects of malaise and fatigue. However, I also noticed that I felt very sad (a deep emptiness that I have never experienced before) for a day or so. That made me wonder about the connection between immune system activation and depression.

Thiamine deficiency can be precipitated by vaccines.  Thiamine supplementation will alleviate the fatigue and depression.  Work up to 300 mg a day.  

Hope this helps.

My doctor at OSU, Dr. Aukerman, indicated that celiac has a severe impact on magnesium levels. He displayed a poster that showed the downward spiral from headaches to depression to suicide. He put his patients on high doses of magnesium. I found that once my celiac was diagnosed (which took 50 years!), and I was taking magnesium, I was far less prone to depression and anxiety.

Thiamine needs magnesium to activate and work properly.  Increasing magnesium consumption or correcting magnesium deficiency can allow thiamine to work properly.  

I'm suffering really bad with Celiac disease along with a cpl auto-immune diseases. Need help understanding why it's affecting my mental health. Please 🥺💔

Katina,

First, chronic health issues are common contributors to mental health issues, particularly depression.

Second, celiac disease typically results in vitamin and mineral deficiencies because of the damage it does to the small bowel lining. The "villi" of the small bowel are damaged and worn down, preventing proper absorption of the nutrition in the food we eat. Other bowel issues often found in conjunction with celiac disease like diarrhea can exacerbate the nutritional deficiency problem because things pass through so quickly there isn't time for their nutritional value to be taken up.