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    Scott Adams

    COVID-19 a Possible Trigger for Celiac Disease in Those with Genetic Risk

    Reviewed and edited by a celiac disease expert.

    A research team predicts a possible rise in celiac disease due to impact of Covid-19 infections.

    COVID-19 a Possible Trigger for Celiac Disease in Those with Genetic Risk - Image: CC BY 2.0--Official U.S. Navy Imagery
    Caption: Image: CC BY 2.0--Official U.S. Navy Imagery

    Celiac.com 06/28/2021 - There is a growing body of data to suggest the intestinal action of SARS-CoV-2, with ciliated cells and intestinal enterocytes serving as target cells, due to high expression of ACE2 and TMPRSS2, could possibly trigger celiac disease in predisposed individuals.

    Indeed, COVID-19 promotes a “cytokine storm” in the intestinal mucosa, triggering epithelial damage that increases barrier permeability, permitting gliadin to "leak" into the intestinal lamina. However, the possible impact of the SARS-CoV-2 infection, and the resulting disease, on celiac disease rates remains unknown, with no data currently available on the development of systemic disorder, or on long-term outcomes. 

    Celiac.com Sponsor (A12):
    A team of researchers recently set out to highlight the potential risk of a rise in celiac disease rates among genetically predisposed subjects following SARS-CoV-2 infection, based on several factors which could promote the development of celiac disease.

    The research team included Chiara Maria Trovato, Monica Montuori, Nicoletta Pietropaoli, and Salvatore Oliva. They are variously affiliated with the Pediatric Gastroenterology and Liver Unit, Maternal and Child Health Department, Sapienza University of Rome, Rome, Italy; and the Hepatology Gastroenterology and Nutrition Unit, "Bambino Gesù" Children Hospital, Rome, Italy. 

    The team used current medical literature to help them hypothesize the role of COVID-19 as a possible trigger for celiac disease development in predisposed individuals. They suggest that genetically predisposed people could be more likely to develop celiac disease following SARS-CoV-2 infection, making COVID-19 a potential driver of increased celiac disease cases in the future.

    An unexpected rise in celiac cases among genetically predisposed individuals in the wake of the COVID-19 pandemic would support the team's hypothesis. Time will tell if they are right. Stay tuned for more stories regarding COVID-19, celiac disease, and related topics.

    Read more in the International Journal of Clinical Practice



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    Guest M. Barrera

    Posted

    I do suffer from a genetic form of Celiac And five weeks after my last dose of Moderna vaccination I experienced a major chronic inflammation in the weakest part of my body which is my both knees which I suffer from osteoarthritis. I have had this condition for over 15 years and it had been managed but this experience was something I had never dealt with before. I could not walk I was practically paralyzed . I could not bend and the pain was excruciating. I have had two episodes of this and both times they gave me prednisone. At this time I have not heard anyone talk about flareups after they get the vaccination. If there is anyone else out there that has experienced any inflammation after the vaccination please post. Doctors are trying to figure out why my C-reactive protein labs so high and it has never been before not even dealing with osteoarthritis for years.

    Thank you

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    Guest Jh51

    Posted

    I have celiac disease. After receiving the first dose of the Pfizer Covid-19 vaccine, I experienced diarrhea. After 2 weeks of this, I ended up in the hospital with pancreatitis. Needless to say, I did not get the second dose. I am so glad someone is connecting the dots between Covid and celiac. 

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    Makky
    2 hours ago, Guest M. Barrera said:

    I do suffer from a genetic form of Celiac And five weeks after my last dose of Moderna vaccination I experienced a major chronic inflammation in the weakest part of my body which is my both knees which I suffer from osteoarthritis. I have had this condition for over 15 years and it had been managed but this experience was something I had never dealt with before. I could not walk I was practically paralyzed . I could not bend and the pain was excruciating. I have had two episodes of this and both times they gave me prednisone. At this time I have not heard anyone talk about flareups after they get the vaccination. If there is anyone else out there that has experienced any inflammation after the vaccination please post. Doctors are trying to figure out why my C-reactive protein labs so high and it has never been before not even dealing with osteoarthritis for years.

    Thank you

    Wishing you healing and no pain 🙏 I was very very pro vax before this happened to me (I still went and ahead and got the second dose right around time of diagnosis) but I truly think that a combination of stress and the vaccine messing with the immune system really set this off for me, I was very healthy and am very young before the celiac symptoms began. I will not be surprised if we see more reports of similar cases (flare ups due to vaccine) in the near future. 

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    Guest germany

    Posted

    On 7/7/2021 at 4:24 PM, Guest Tina Brown said:

    I got a vaccine while living in Germany in 2013. I got very sick afterwards.  I was sick for several months. By 2014 I started having serious intestinal issues. By 2015 when I was back in the States,  by whole body was a wreck. 

    I went in for testing, that took over a year for all the tests. Finally in 2016, after losing my gallbladder,  I was tested for celiac disease, and it was positive.  I even took the DNA test, it too was positive. 

    Afterwards my doctor said that my celiac disease was more than likely triggered by either the vaccine or the virus,  or both since they were related. 

    He said that it is quite common for people to trigger an Autoimmune disease by a traumatic event, a vaccine or a serious illness.  This is especially true for late life diagnosis,  which mine was. 

    Our son tested negative for celiac, 3 months after his test he got the MMR vaccine, and then 3 months after the MMR vaccine he tested positive for celiac. N=1 but that 1 is pretty important to me. Possibility also applies to dogs & cats Open Original Shared Link Dr. Marty Goldstein has some great books on this topic

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    Guest Angela

    Posted

    On 7/7/2021 at 6:14 AM, Guest Tammie said:

    I truly believe this could be why I am having such digestive and mental health issues after contracting Covid19 Feb 2020. I have been trying to heal my gut through probiotics. I am now going to set up a Gluten test. Thank You for the information.

    Unfortunately eating probiotics is not the way to heal, I have had celiac since 1990. Removing gluten entirely, eating less grain/processed foods and raising your fruits and vegetables and other foods (which have natural probiotics) as well as doing grounding techniques and reducing stress perhaps by walking daily or light workouts, being exposed and taking in the sun for 10 min per day without sunscreen, and getting 8+ hours of sleep so you can heal is so important! If you’re eating probiotics, eat it in your food like pickled foods such as sauerkraut. Also, eliminating oats and dairy is very important as they can both be triggers for inflammation. Take liquid turmeric and resveratrol to bring down inflammation and allow your gut to heal. This can take upwards of 6-12 months so be patient, don’t be too hard on yourself, and don’t listen to people who aren’t going through this challenging time themselves, they always want to rush your recovery and that is just not how this works. Best!

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    knitty kitty

    Covid patients have been found to suffer from Thiamine deficiency.

    There are many studies showing high dose Thiamine will help with the after effects of Covid.  

    Please read....

    Open Original Shared Link

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    Scott Adams
    2 hours ago, Guest germany said:

    Our son tested negative for celiac, 3 months after his test he got the MMR vaccine, and then 3 months after the MMR vaccine he tested positive for celiac. N=1 but that 1 is pretty important to me. Possibility also applies to dogs & cats Open Original Shared Link Dr. Marty Goldstein has some great books on this topic

    Correlation does not equal causation. For a long time people tried to link autism as caused by vaccines, and no causation has been found. Lots of things will happen to your kids after they get a vaccine, none of which will be caused by the vaccine, except in your son's case, his not getting measles, mumps or rubella (all of which are dangerous and very contagious diseases with known, serious side effects). Small pox has been wiped off the planet, and we came close with wiping out polio. The dog article you link to doesn't apply at all to the human vaccines that you mention, and is simply a red herring.

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    sandbtmytoes
    16 minutes ago, Scott Adams said:

    Correlation does not equal causation. For a long time people tried to link autism as caused by vaccines, and no causation has been found. Lots of things will happen to your kids after they get a vaccine, none of which will be caused by the vaccine, except in your son's case, his not getting measles, mumps or rubella (all of which are dangerous and very contagious diseases with known, serious side effects). Small pox has been wiped off the planet, and we came close with wiping out polio. The dog article you link to doesn't apply at all to the human vaccines that you mention, and is simply a red herring.

    Scott, 

    Since the suspected autism link was from the MMR vaccine, and many autistic symptoms improve or disappear on the gluten free diet, might there be a link between the MMR vaccine turning on celiac genes and undiagnosed celiac causing the autism problems after vaccination, as Guest Germany thinks that vaccine turned on her son’s celiac?

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    knitty kitty
    11 minutes ago, sandbtmytoes said:

    Scott, 

    Since the suspected autism link was from the MMR vaccine, and many autistic symptoms improve or disappear on the gluten free diet, might there be a link between the MMR vaccine turning on celiac genes and undiagnosed celiac causing the autism problems after vaccination, as Guest Germany thinks that vaccine turned on her son’s celiac?

    This article explains how vaccination can be a precipitating cause of health problems because..... well, read the article...

    Open Original Shared Link

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    Scott Adams

    There is no known link between the MMR vaccine and getting celiac disease, or for that matter, any other condition that I'm aware of. When it comes to vaccines, please share peer reviewed published scientific studies, not "hormeonesmatter.com" type links.

    If such a study gets published, we'll be happy to cover it here. Of course you can speculate eternally on such a topic...could MMR cause this, or that, or trigger this?? But it is only pure speculation.

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    knitty kitty
    6 minutes ago, Scott Adams said:

    There is no known link between the MMR vaccine and getting celiac disease, or for that matter, any other condition that I'm aware of. When it comes to vaccines, please share peer reviewed published scientific studies, not "hormeonesmatter.com" type links.

    Links to Dr. Lonsdale's published on PubMed scientific articles are linked in his articles.  

    Nonetheless, apologies.

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    Guest Price

    Posted

    On 7/7/2021 at 10:11 AM, DevilGluten said:

    I 100% believe this is a possibility.  My celiac kicked in when I was 30, after I randomly got pneumonia and a lung abscess.  I was in the hospital for weeks on IV antibiotics.  I got tested for everything you can imagine (HIV, tuberculosis, hepatitis, etc).  because they didn't understand why a healthy 30 year old guy would get pneumonia and an abscess.  This was in 2003.  Maybe I had Covid-18 back then :)

    Before I got sick I used to eat bread and pasta like a madman with no issues.  Afterwards, all my celiac symptoms started.  So I always wondered what was the cause and effect.  Was it the pneumonia that caused the celiac to kick in?  Was it the months of antibiotics I was on?  (I was on Avelox which was since been recalled for a number of issues).  Was my immune system just a time bomb waiting to go off and it all went to hell at one time?  Not sure, but I can totally believe an infectious disease like Covid could trigger dormant celiac in some people that are prone to it.

    There is a possibility that the pneumonia didn’t help your situation, but in all of my research and journey through Celiac I have discovered much research pointing to antibiotics being the root of people having gut issues after being sick. Antibiotics also destroy the good bacteria in your gut leaving you more prone to autoimmune issues in the near future. I had a similar trigging of celiac after doctors couldn’t figure out if I had pneumonia or bronchitis and put me on antibiotics for over a month.  

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  • About Me

    Scott Adams

    Scott Adams was diagnosed with celiac disease in 1994, and, due to the nearly total lack of information available at that time, was forced to become an expert on the disease in order to recover. In 1995 he launched the site that later became Celiac.com to help as many people as possible with celiac disease get diagnosed so they can begin to live happy, healthy gluten-free lives.  He is co-author of the book Cereal Killers, and founder and publisher of the (formerly paper) newsletter Journal of Gluten Sensitivity. In 1998 he founded The Gluten-Free Mall which he sold in 2014. Celiac.com does not sell any products, and is 100% advertiser supported.


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