Does Vitamin D Play a Role in Celiac Disease Onset?

Scott,

Thanks for sharing this research.

Here is another article that might help others entitled "Vitamin D and the anti-viral state"

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3308600/

I quoted the full citation so others can see at what level OHD Vitamin D has been shown to be an immune regulator.

Generally it is believed (for those whose don't have time to scan/read it) in it's entirety.

That at or below 20 OHD your Vitamin D level's could be triggering your immune reaction. And why below 20 OHD is considered insufficient.

There are a summary of many studies in this excellent article on Vitamin D and the Antiviral state.

It should be noted that Low Vitamin D levels have also been linked with EBV.

See their paragraph on this connection quoting.

"Evidence for vitamin D influence on Epstein Barr virus

Studies have suggested a link between multiple sclerosis (MS) and Epstein-Barr virus (EBV), thus vitamin D levels may play a role in the development of MS.93,94 This topic was reviewed by Trygve Holmoy in Medical Hypotheses.95 Holmoy notes that MS risk is associated with low vitamin D status and EBV infection. He proposes that vitamin D modulates the immune response to EBV and suppresses activation of auto-reactive T cells that may contribute to MS pathology."

And in Circa 2018 Epstein Barr Virus aka EBV was linked to Celiac disease.

https://medicalxpress.com/news/2018-04-epstein-barr-virus-linked-diseases.html

I hope this is helpful but it is not medical advice.

Posterboy,

Celiac disease is genetic. It doesn't just develop so I'm confused when it's stated that vitamin D causes celiac when it doesn't just develop. Thanks

Over 20% of the population has the genetic markers for celiac disease, yet only ~1% will get it. Environmental triggers like certain viruses have been shown to be a "trigger" of the disease in some people. This article explores the role of vitamin D in the trigger of celiac disease in those who are genetically susceptible. 

I has low vit D when diagnosed with Celiac..was told that because of intestinal damage it was not absorbing fat soluble vitamins like Vit.D..that was back in 2006..

So I was under the impression that my low Vit D was due to Celiac..not Celiac due to low Vit D..all healed now and Vit D normal

I respond well to light therapy or sun but Vitamin D pills don’t seem to have an effect.  My nurse practitioner wants to give me two months worth of high dosages of Vitamin D but I’ve read that Celiacs the Vitamin D just gets stuck, unusable, in the liver because Celiacs don’t process the fat that carries it.  Is that only true of active Celiac Disease?  Mine is currently well controlled.

1 hour ago, Guest Margo said:

I respond well to light therapy or sun but Vitamin D pills don’t seem to have an effect.  My nurse practitioner wants to give me two months worth of high dosages of Vitamin D but I’ve read that Celiacs the Vitamin D just gets stuck, unusable, in the liver because Celiacs don’t process the fat that carries it.  Is that only true of active Celiac Disease?  Mine is currently well controlled.

How do you know that your celiac disease is well controlled?  Do you get repeat antibodies testing or a repeat endoscopy?  Are you basing it on symptoms alone?  If you are well controlled, you should be able to absorb vitamins and minerals.  If not, you might have an additional illnesses.  Having more than one autoimmune disorder is common.  
 

I have taken no Vitamin D supplements.  I live in Southern California.  I make a point to get daily sun for 10 minutes or so.  My D level does reduce in the winter, but never goes out of the normal range.  Newer research even with COVID 19, indicates that smaller doses of Vitamin D is better than larger doses (google it).  Get in the sun.  You can generate D fast!  There are few food sources that contain vitamin D naturally, so consider consuming more of those.   

On 7/13/2020 at 7:51 AM, Guest Roland. said:

Celiac disease is genetic. It doesn't just develop so I'm confused when it's stated that vitamin D causes celiac when it doesn't just develop. Thanks

No one knows exactly what triggers celiac disease.  This article just suggests that more research is needed.  

18 hours ago, Guest Rosalia said:

I has low vit D when diagnosed with Celiac..was told that because of intestinal damage it was not absorbing fat soluble vitamins like Vit.D..that was back in 2006..

So I was under the impression that my low Vit D was due to Celiac..not Celiac due to low Vit D..all healed now and Vit D normal

 

Get your Vitamin D from the sun!   Obtaining it from food sources is possible, but the sun does a much better job.   Vitamin D can be low because of where you live or how much sunscreen you wear.  I am celiac.  Was never low in Vitamin D, but I am in the sun daily for 10 minutes.  I wear sunscreen only when I am going to be outdoors for longer periods of time.  

3 hours ago, Guest Margo said:

I respond well to light therapy or sun but Vitamin D pills don’t seem to have an effect.  My nurse practitioner wants to give me two months worth of high dosages of Vitamin D but I’ve read that Celiacs the Vitamin D just gets stuck, unusable, in the liver because Celiacs don’t process the fat that carries it.  Is that only true of active Celiac Disease?  Mine is currently well controlled.

Margo,

Cyclinglady has given you good advise.....

Your skin is very efficient at making Vitamin D from Sunlight....

But if that is not enough consider taking some Magnesium Citrate (always with meals)...or Magnesium Glycinate anytime (without meals is ok for this form)....

Here is an article about it....

https://www.news-medical.net/news/20110615/Magnesium-essential-for-absorption-and-metabolism-of-vitamin-D-and-calcium.aspx

Magnesium is a Co-Factor for Vitamin D metabolism in the body......it might help your low Vitamin D levels....

Mine fluctuate as Cyclinglady noted seasonally.....It is called...Seasonal Affective Disorder.

https://www.medicalnewstoday.com/articles/286496 

I hope this is helpful but it is not medical advise.

Posterboy,

Interesting information.  My Vitamin D dropped to 5 a couple years before I developed anemia and was finally diagnosed.  I think, however, I may have had celiac for many years before that. 

I think that boron is a missing key to some people's health with regard to vitamin D.  There is a link between vitamin D and boron that is important.   It seems like boron affects levels of other nutrients in the body and how vitamin D is used by the body.  It could be that without adequate boron levels vitamin D cannot be efficiently used by the body.  Just one study  showing a link to mineral levels below.  If you are a rat, this is important information for you.  Rats on the same diet but lacking boron showed lower available levels of phosphorus and calcium.

Open Original Shared Link

Effect of boron on vitamin D deficient rats

M Hegsted 1, M J Keenan, F Siver, P Wozniak 

Affiliations expand

PMID: 1713047

DOI: 10.1007/BF02990471

Abstract

The effects of different levels of dietary boron were determined in vitamin D deficient rats. Vitamin D deficient diets containing either 0.158 ppm or 2.72 ppm of boron were fed to rats for 11 w, and calcium, magnesium, and phosphorus apparent absorption and balance were measured in the twelfth week. Higher apparent absorption and balance values for calcium and phosphorus were observed in the rats with higher dietary boron, but very few differences were seen in body wt, organ wt, and bone parameters. Balance measurements represented the present status of the rats after 12 w on the diets, but other measurements represented an accumulation over the lifetime of the rat, including a suckling period with ample vitamin D and boron. The data demonstrated that when rats are vitamin D deficient, as indicated by hypocalcemia, the level of boron in the diet affects mineral balance.

GFinDC,

Thank you for that....nice research on Boron.

I think you have quoted that research before.....Boron is an often overlooked  nutrient for Bone Density....

But I have found Selenium is also important for Vitamin D.

Here is a nice article about it...

Open Original Shared Link

They show how Vitamin D can help regulate our immune system.....this effect has been shown in Hashimoto's..

quoting from the article...

"They also measured levels of anti-TPO. It turned out that those women who had taken vitamin D had elevated levels of vitamin D in their blood, but their levels of anti-TPO had gone down at the same time. Therefore, the researchers concluded that supplementing with 50 micrograms of vitamin D daily can reduce autoimmune reactions in women with Hashimoto’s disease, who are already receiving medical care and have normal vitamin D levels in their blood."

Or what has been set as Normal levels....but actually could be too low....see the article about "Living on the Plateau" by Dr. Heaney

Knitty Kitty has noted this....the level for normal Vitamin D levels are too low....

They (the article and the Danish) argue for a higher OHD number to help control Autoimmune diseases....

Also see this article about how Vitamin D acts as an Immune Regulator...

 Open Original Shared Link

The number I had read was below 10 OHD.....but it might even be higher than that...

See here where Dr. Heaney argues that the Insufficiency OHD Levels for Vitamin D are too low!

Open Original Shared Link

He calls it "Living on the Plateau"

I hope this is helpful but it is not medical advise.

Posterboy,