First Wave BioPharma to Present Two Abstracts on Celiac Disease Research at 2024 Digestive Disease Week (DDW) Conference

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By Jefferson Adams

April 24
By Jefferson Adams • April 24

First Wave BioPharma to Present Two Abstracts on Celiac Disease Research at 2024 Digestive Disease Week (DDW) Conference

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Reviewed and edited by a celiac disease expert.

First Wave BioPharma, a leading biopharmaceutical company specializing in gastrointestinal (GI) diseases, is set to unveil groundbreaking research on celiac disease at the upcoming 2024 Digestive Disease Week (DDW) Conference.

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Ceiling detail, Washington DC Metro by o palsson is licensed under CC BY 2.0.

Celiac.com 04/24/2024 - First Wave BioPharma, a leading biopharmaceutical company specializing in gastrointestinal (GI) diseases, is set to unveil groundbreaking research on celiac disease at the upcoming 2024 Digestive Disease Week (DDW) Conference. This announcement comes with the acceptance of two abstracts for presentation at the esteemed event, scheduled for May 18-21, 2024, in Washington, D.C.

The first abstract, titled "A Composite Mucosal Scale for Celiac Disease Encompassing both Morphology and Inflammation," will introduce VCIEL, a novel quantitative composite scale. VCIEL combines key histologic measurements—villus height to crypt depth ratio (Vh:celiac disease) and density of intraepithelial lymphocytes (IEL)—to enhance the accuracy of assessing small intestinal mucosal health in celiac disease patients. This innovation promises to revolutionize clinical trials by providing more precise endpoint measurements.

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The second abstract, "Dynamics of Serologic Change to Gluten in Celiac Disease Patients," delves into the complexities of diagnosing celiac disease. The study draws from a vast clinical database to investigate critical aspects, including the impact of gluten reintroduction on seropositivity and the correlation between different tTG-IgA assays. These findings have significant implications for improving diagnostic accuracy and patient management strategies.

James Sapirstein, Chairman and CEO of First Wave BioPharma, expressed excitement about the potential impact of their research on advancing the diagnosis and management of celiac disease. Jack Syage, PhD, President and Chief Operating Officer of First Wave, emphasized the validation of their work through the invitation to present at DDW 2024—a testament to the company's commitment to enhancing understanding and treatment options for individuals with celiac disease.

This pioneering research from First Wave BioPharma represents a significant step forward in the quest for precision diagnostics and targeted therapies for celiac disease, offering hope for improved outcomes and quality of life for affected individuals.

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About Me

Jefferson Adams is Celiac.com's senior writer and Digital Content Director. He earned his B.A. and M.F.A. at Arizona State University. His articles, essays, poems, stories and book reviews have appeared in numerous magazines, journals, and websites, including North American Project, Antioch Review, Caliban, Mississippi Review, Slate, and more. He is the author of more than 2,500 articles on celiac disease. His university coursework includes studies in science, scientific methodology, biology, anatomy, physiology, medicine, logic, and advanced research. He previously devised health and medical content for Colgate, Dove, Pfizer, Sharecare, Walgreens, and more. Jefferson has spoken about celiac disease to the media, including an appearance on the KQED radio show Forum, and is the editor of numerous books, including "Cereal Killers" by Scott Adams and Ron Hoggan, Ed.D.

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