See who reacted to this (25016) - How Refining the Gluten Challenge May Help Improve Diagnostics for Celiac Disease

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1. Scott Adams
  July 12
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About Me

Jefferson Adams is Celiac.com's senior writer and Digital Content Director. He earned his B.A. and M.F.A. at Arizona State University. His articles, essays, poems, stories and book reviews have appeared in numerous magazines, journals, and websites, including North American Project, Antioch Review, Caliban, Mississippi Review, Slate, and more. He is the author of more than 2,500 articles on celiac disease. His university coursework includes studies in science, scientific methodology, biology, anatomy, physiology, medicine, logic, and advanced research. He previously devised health and medical content for Colgate, Dove, Pfizer, Sharecare, Walgreens, and more. Jefferson has spoken about celiac disease to the media, including an appearance on the KQED radio show Forum, and is the editor of numerous books, including "Cereal Killers" by Scott Adams and Ron Hoggan, Ed.D.

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Related Articles
What is a Gluten Challenge and How Long Must it Last?
Celiac.com 06/04/2020 - Currently, in order to properly diagnose celiac disease based on serology and duodenal histology, doctors need patients to be on gluten-containing diets, even if they are causing symptoms, and this is called a "gluten challenge." This is a problem for many people, especially those who have already given up gluten, and see benefits from the gluten-free diet. For those people, going back on gluten for several weeks can be demoralizing. For many, it's a deal breaker. This can present challenges for doctors attempting to diagnose celiac disease.
According to the University of Chicago Celiac Disease Center, a gluten challenge should be done as follows:
Eat gluten prior to celiac disease blood tests: The amount and length of time can vary, but is somewhere ...

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Microsoft and Adaptive Biotechnologies Activate AI Engine for Breakthrough Diagnostic Blood Test
Celiac.com 02/13/2019 - Microsoft and Adaptive Biotechnologies have announced a major milestone in their efforts to develop a blood test capable of diagnosing numerous diseases with a single blood sample.
The companies are attempting to use data to map the immune system’s response to perceived threats. By cataloging the body’s immune responses to certain threats, and how those responses are reflected in the blood, they hope to create a single test to diagnose numerous diseases, including type 1 diabetes, celiac disease, ovarian cancer, pancreatic cancer and Lyme disease.
To do this, they need huge amounts of data, and massive computing power for data sorting. The team’s artificial intelligence programs are central to their data crunching efforts. The team announced recent...

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Did You Know: Should I Undertake a Gluten Challenge?
Celiac.com 02/08/2019 - I've been reading a lot about the gluten challenge, which makes my stomach curl. It is rare that someone with celiac disease will have a negative antibody test result. If your tests were negative but you continue to experience symptoms, consult your physician and undergo further medical evaluation. Don't just continue to suffer—keep exploring. You are not alone in this "Gluten Maze". That title can be attributed to me over thirty years ago, and I am still using it, particularly when answering the phone lines at our local hospital's dietitian office. I feel so sorry for the young people who phone in regarding symptoms that seem so common to me, but not to people who are new to celiac disease. Also for those who have stopped searching after consulting only with their f...

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Elevated Serum Interleukin-2 After Gluten Challenge Can Help Monitor Celiac Disease
Celiac.com 12/04/2019 - There still is no easy and accurate way to monitor and diagnose celiac disease in patients who've been on a gluten-free diet for a while. Celiac disease patients on a gluten-free diet experience reactions to gluten, but researchers really don't understanding those reactions in any meaningful way. Systemic cytokine release was recently linked to reactivation of gluten immunity in celiac disease.
A team of researchers recently set out to define the nature and time-course of symptoms and interleukin-2 changes specific for celiac disease patients. Their study shows that interleukin-2 assessment could help doctors monitor and diagnose celiac disease in patients already following a gluten-free diet.
The research team included Jason A. Tye-Din, A. James M...

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Recent Activity
1. 4 hours ago - Elliebee replied to Elliebee's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
  13
  
  Does Hashimoto’s Hypothyroidism elevate Ttg levels ? I have had 3 blood test results where ttg levels are around 39-43 (range 0-19). The first test was in 2021 before I was diagnosed with autoimmune thyroid disease. I had an endos
  
  Benefits are national but different Drs and health trusts interpret them differently unfortunately. Those diagnosed are supposed to get an annual review, Dexa scans every 2/3 years (one on diagnosis) , annual blood tests to check for vit deficiency etc. But very few seem to get these ! Advice from gastroenterologist: I suggest...
2. 6 hours ago - sboo replied to GeordieGeezer's topic in Food Intolerance & Leaky Gut
  16
  
  Anybody else have a similar experience...theories welcome as its something which i dont really understand.....
  
  I had a couple of friends who after a course of antibiotics were struggling to eat much. The anti biotucs can kill off alit of your gut bacteria and it took quite some time to build these up again but after a year or so they could eat normally again.
3. 10 hours ago - trents replied to Patrick-Tyler's topic in Gluten-Free Restaurants
  1
  
  Is McDonald's Safe for Gluten-Free Orders?
  
  Welcome to the forum, @Patrick-Tyler! I think most of us are at least a little nervous about eating at fast food restaurants, even McDonalds, who claims to offer gluten-free fries. What does that mean? Only that gluten is not an intentional ingredient or does it also mean the fries are cooked in a dedicated frier? This has long been a question kicked...
4. 10 hours ago - Patrick-Tyler posted a topic in Gluten-Free Restaurants
  1
  
  Is McDonald's Safe for Gluten-Free Orders?
  
  Hai Community, I have doubt on McDonald's? even it is dedicated to fryers and added gluten-free buns, I’d still be nervous about ordering there for my daughter who has celiac. Anyone else feel uneasy about trusting fast food places with cross-contamination? Would love to hear if anyone’s had good (or bad) experiences with gluten-free options at McD...
5. 12 hours ago - Nogluten4thisgirl posted a topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
  0
  
  Is the gluten challenge worth it with what I’ve got going on here?
  
  I got my dna test back and here are the results: HLA-DQA1, ALLELE 1 Value 01:02 HLA-DQA1, ALLELE 2 Value 02:01 HLA-DQB1, ALLELE 1 Value 02:02 HLA-DQB1, ALLELE 2 Value 06:02 I had a CT scan, which nothing was found except for a large bowel fecal mass, which doesn’t surprise me because I get super constipated and m...