Is Excedrin Gluten-Free?

Celiac.com 09/02/2021 - We get a lot of questions from people wondering which brands of over the counter drugs are gluten-free and safe for people with celiac disease. We recently answered questions about whether products like Advil PM and Tylenol are gluten-free--they are.

We also get a lot of questions about Excedrin. Specifically, is Excedrin gluten-free and safe for people with celiac disease or gluten intolerance? The simple answer is yes.

Celiac.com Sponsor (A12):
Excedrin, and many Excedrin products are made without gluten-ingredients, and are considered gluten-free. However, as with any products, formulations may change, so check labels and ingredients, and choose carefully.

Excedrin products made without gluten, and considered gluten-free include:

Excedrin Extra Strength 
Clinically proven formula of 2 pain fighters plus a booster. For some, relief starts in just 15 minutes

Active ingredients:
Acetaminophen 250mg
Aspirin 250 mg – Non-Steroidal Anti-Inflammatory Drug (NSAID)
Caffeine 65 mg

Inactive ingredients:
corn starch, crospovidone, hypromellose, microcrystalline cellulose, povidone, propylene glycol, sodium lauryl sulfate, sodium starch glycolate, stearic acid, titanium dioxide

Excedrin Migraine
The no. 1 Neurologist recommended OTC treatment for migraines.* For some, relieves pain starting in just 30 minutes, plus nausea and sensitivity to light and/or sound. *AMONG OTC MEDICINE FOR MIGRAINES IQVIA, INC., 2018

Active ingredients:
Acetaminophen 250 mg
Aspirin 250 mg –Non-Steroidal Anti-Inflammatory Drug (NSAID)
Caffeine 65 mg

Inactive ingredients:
benzoic acid, carnauba wax, FD&C blue #1, hypromellose, light mineral oil, low-substituted hydroxypropyl cellulose, microcrystalline cellulose, polysorbate 20, povidone, propylene glycol, simethicone, sorbitan monolaurate, stearic acid, titanium dioxide.

Excedrin Tension Headache 
Relief for tension headaches with pain in the neck and shoulders. Aspirin-free.

Active ingredients:
Acetaminophen 500 mg
Caffeine 65 mg

Inactive ingredients:
Carnauba wax, D&C red # 27 aluminum lake, FD&C yellow #6 aluminum lake, FD&C blue #2 aluminum lake, magnesium stearate acid, microcrystalline cellulose, polyethylene glycol, polyvinyl alcohol, sodium starch glycolate, stearic acid, talc, titanium dioxide.

Excedrin PM Headache

Active ingredients:
Acetaminophen 250 mg
Aspirin 250 mg – Non-Steroidal Anti-Inflammatory Drug (NSAID)
Diphenhydramine citrate 38 mg

Inactive ingredients:
benzoic acid, calcium carbonate, FD&C blue, #1 aluminum lake, hydroxypropyl cellulose, low substituted hypro mellose, magnesium stearate, maltodextrin, medium chain-triglycerides, polydextrose, polysorbate 80, povidone, pre-gelatinized cornstarch, silicified microcrystalline cellulose, stearic acid, talc, titanium dioxide, yellow iron oxide, zinc stearate.