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  • Jefferson Adams
    Jefferson Adams

    Limiting or Eliminating Gluten and FODMAPs May Improve Mental Disorders

    Reviewed and edited by a celiac disease expert.

    A new study indicates that Limiting or eliminating FODMAPs in the diet might be beneficial for symptoms such as depression.

    Limiting or Eliminating Gluten and FODMAPs May Improve Mental Disorders - Blackbird. Image: CC BY-SA 2.0--Thomas Berg
    Caption: Blackbird. Image: CC BY-SA 2.0--Thomas Berg

    Celiac.com 07/06/2022 - More and more people are avoiding gluten and FODMAP food components (fermentable oligosaccharides, disaccharides, monosaccharides and polyols) over concerns about their potential connection to celiac-like reactions in the gut. 

    In recent years, gluten-free diets (GFD) and low-FODMAP diets (LFD) have become more popular across the globe. This is due to intolerances or allergies in some people, but also due to the direct influence of marketing movements or diet trends on eating choices. 

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    At the same time, understanding, diagnosing and treating neurological and psychiatric diseases is becoming more important in numerous countries. A number of researchers have started to examine FODMAPs for that reason. 

    Because of this, the research team conducted a bibliographic systematic review to see if there is a pathophysiological relationship between consumption of gluten or FODMAPs and mental disorders. 

    The research team included Egoitz Aranburu; Silvia Matias; Edurne Simón; Idoia Larretxi; Olaia Martínez; María Ángeles Bustamante; María del Pilar Fernández-Gil; and Jonatan Miranda.

    They are variously affiliated with the Gluten Analysis Laboratory of the University of the Basque Country, Department of Nutrition and Food Science, University of the Basque Country in Vitoria, Spain; the GLUTEN3S Research Group, Department of Nutrition and Food Science, University of the Basque Country in Vitoria, Spain; the Bioaraba, Nutrición y Seguridad Alimentaria, in Vitoria, Spain; and the Centro Integral de Atención a Mayores San Prudencio in Vitoria-Gasteiz, Spain.

    The team's review gathered data from clinical and randomized controlled trials, based on the PRISMA statement, published since 2012. 

    Their analysis found that limiting or ruling out gluten or FODMAPs may improve symptoms such as depression, anxiety, or cognition deficiency, and to a lesser extent for schizophrenia and the autism spectrum. 

    Nevertheless, further studies are needed to obtain completely reliable conclusions.

    Read more in Nutrients 2021, 13(6), 1894.
     



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    Guest Marianne

    Posted

    But it has been noted by the scientific community that limiting gluten intake improves the condition of various mental disorders since the 1960s. So one might ask why has this study taken so long to be conducted, and why bother with a study that gives no more information than we already had on the subject? Plus,I would like to point out that whilst it is worth studying whether gluten and FODMAPS are linked to causality in depression, there is little more depressing than a life where every day you have some form of nausea, vomiting, stomach pain, acid reflux, diarrhoea or constipation. In fact, you might actually ask who wouldn’t be depressed? 

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    trents
    1 hour ago, Guest Marianne said:

    But it has been noted by the scientific community that limiting gluten intake improves the condition of various mental disorders since the 1960s. So one might ask why has this study taken so long to be conducted, and why bother with a study that gives no more information than we already had on the subject? Plus,I would like to point out that whilst it is worth studying whether gluten and FODMAPS are linked to causality in depression, there is little more depressing than a life where every day you have some form of nausea, vomiting, stomach pain, acid reflux, diarrhoea or constipation. In fact, you might actually ask who wouldn’t be depressed? 

    A lot of things have been known for a long time but still most people are still totally unaware of them. This article may be the first exposure that many in the gluten sensitive/celiac community have ever had to the term FODMAP.

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    Scott Adams
    2 hours ago, Guest Marianne said:

    But it has been noted by the scientific community that limiting gluten intake improves the condition of various mental disorders since the 1960s. So one might ask why has this study taken so long to be conducted, and why bother with a study that gives no more information than we already had on the subject? Plus,I would like to point out that whilst it is worth studying whether gluten and FODMAPS are linked to causality in depression, there is little more depressing than a life where every day you have some form of nausea, vomiting, stomach pain, acid reflux, diarrhoea or constipation. In fact, you might actually ask who wouldn’t be depressed? 

    This study focuses on the effects of the low FODMAP diet, and not celiac disease. As far as I know, not too much research has been done in this regard on the low FODMAP diet.

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    Suzisqueue
    On 7/11/2022 at 9:55 AM, Scott Adams said:

    This study focuses on the effects of the low FODMAP diet, and not celiac disease. As far as I know, not too much research has been done in this regard on the low FODMAP diet.

    FODMAP has been really helpful for my autism, celiacs and GI issues. I have a no grain, no sugar, and now no dairy diet. My daughter calls it the 'sucks to be you diet'. 

    I was hoping this study might have focused on Gut microflora. That's really where all of it is. A little critters in you intestines and colon. Interesting stuff.

    Great books to read:

    Mark Gershons: 'The Second Brain'

    William Phillips, 'Brain Allergies"

     

    Peace out!!✌️

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    CBird

    I discovered needing to be gluten free in 2010 at 62yr old. I'd experienced bouts of depression, anxiety, and panic attacks since my early 20s. I actually was on meds for anxiety/panic and had to go off due to loss of medical insurance at that point. No more panic attacks, anxiety, depression AND no more painful IBS trips to the emergency room. I also became 'regular' (bowels), and after two years noticed I could read scientific reports that I hadn't been able to focus on until then. MY LIFE CHANGED!
    My sister had nearly died, starving to death, in 1948 at 6mo old at Kaiser Oakland. A new doc from Johns Hopkins suggested they try a gluten free diet; she had celiac. I have NCGS! I never in my wildest imagination thought her story was also my story. No only my story…
    Now my daughter also needs to be gluten free. In her mid 40s now she'd been in and out of the hospital with indigestion so bad she couldn't keep water down. We encouraged her to see functional medicines docs when regular testing didn't show anything. She hasn't been back to the hospital in over a year now. Her symptoms are very different than mine, she never had anxiety/panic, only depression once in a great while.
    So, in my case I know for a FACT that mental health is affected by gluten issues!

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    Scott Adams

    @CBird it's amazing that in 1948 your sister was properly treated for celiac disease. In some ways I find it rather depressing that here we are in 2022, and MANY doctors still miss proper testing for celiac disease, and the average time to diagnosis is still over 5 years after symptom onset. It seems like it should be a lot easier by now.

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  • About Me

    Jefferson Adams

    Jefferson Adams is Celiac.com's senior writer and Digital Content Director. He earned his B.A. and M.F.A. at Arizona State University. His articles, essays, poems, stories and book reviews have appeared in numerous magazines, journals, and websites, including North American Project, Antioch Review, Caliban, Mississippi Review, Slate, and more. He is the author of more than 2,500 articles on celiac disease. His university coursework includes studies in science, scientific methodology, biology, anatomy, physiology, medicine, logic, and advanced research. He previously devised health and medical content for Colgate, Dove, Pfizer, Sharecare, Walgreens, and more. Jefferson has spoken about celiac disease to the media, including an appearance on the KQED radio show Forum, and is the editor of numerous books, including "Cereal Killers" by Scott Adams and Ron Hoggan, Ed.D.

    >VIEW ALL ARTICLES BY JEFFERSON ADAMS

     


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