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  • Jefferson Adams
    Jefferson Adams

    Man Claims Hookworm Treatment Led to Remission of Celiac Disease

    Reviewed and edited by a celiac disease expert.

    Can hookworms really trigger remission of celiac disease? Yes, according to a man who says he's living symptom-free since receiving hookworm treatment for his celiac disease. 

    Man Claims Hookworm Treatment Led to Remission of Celiac Disease - Hookworm. Image: CC BY 2.0--Michael Wunderli
    Caption: Hookworm. Image: CC BY 2.0--Michael Wunderli

    Celiac.com 12/16/2022 - Recently, an interesting discussion thread popped onto our celiac disease and gluten-free forum. A member of the forum, going by the handle @dixonpete, claims his celiac disease went into remission after treatment with hookworms.

    Moreover, he claims that he is essentially cured, and able to eat gluten with no side effects, and has had at least one recent negative follow up tTG antibody test to back this up.

    History of Hookworm Infection to Treat Celiac Disease

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    We've done more than a few articles on the potential to use hookworms to treat celiac disease. We've done a number of articles on hookworms as the potential future of celiac disease treatment, including: 

    Previously, we'd only reported data from various studies, some of which looked promising. Until recently we had never heard directly from anyone claiming to have gone through hookworm treatment firsthand.

    Because he is the first person we've heard from who claims direct experience with hookworm treatment for celiac disease, the information furnished by @dixonpete to the thread might be of interest to anyone who might be interested in the possibility of receiving hookworm treatment.

    Hookworms seem to work, at least partly, by blocking the inflammatory response in the gut of the host. One of the benefits of this treatment is that the hookworms may also block the gut's immune response to gluten in people with celiac disease.

    Could Hookworm Treatment Allow Celiacs to Eat Gluten Again?

    At this time, there's no data to confirm that hookworm treatment "cures" celiac disease in the classic sense of the word. In theory, if the hookworms were eliminated, then the celiac disease could return. And the hookworms don't reproduce, so you need just the right amount in the gut, but not too much.

    The current hypothesis is that the hookworms simply block the immune inflammatory response when people with celiac disease eat gluten. But even that remains unclear, and not well-supported by data. Clearly more studies need to be done to verify whether hookworms present a viable alternative for people with celiac disease.  A single example of this possibly working in real life isn't enough data to support the claim that the treatment should work for all celiacs. In fact, @dixonpete admits himself that he was suffering from both celiac disease and other conditions that drove his decision. Still, it's a compelling story. For more information, read the full discussion thread and the related articles.

    If hookworms prove to be effective treatment for celiac disease, would you be willing to consider a hookworm infection to treat your celiac disease? Let us know in the comments below.  



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    Blue-Sky

    Hookworms can enter through someone's foot...travel up their leg...eat through their lungs...get coughed up...then swallowed make their way to the small intestine and grow there.  😅😁

    They cause major blood loss do to internal bleeding. I am not quite sure how people survive hookworm infections.

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    dixonpete

    People use Necator americanus hookworms for Helminthic Therapy. They are well-behaved and actually use very little blood. In addition, the modern standard is to use very few hookworm larvae, usually starting with just 5. I've never noticed mine.

    I do notice all the gluten products I now get to eat and the absence of colitis. Plus, living in fear of other people's breadcrumbs sucked.

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    John Scott
    On 12/16/2022 at 9:45 PM, Blue-Sky said:

    Hookworms can enter through someone's foot...travel up their leg...eat through their lungs...get coughed up...then swallowed make their way to the small intestine and grow there.  😅😁

    They cause major blood loss do to internal bleeding. I am not quite sure how people survive hookworm infections.

    The hookworm species used in helminthic therapy - Necator americanus - do not cause "major blood loss". If you're interested, you can read the details about the minuscule amount of blood that the NA take as food, here: 
    Do hookworms cause excessive blood loss and anaemia/anemia?
    https://helminthictherapywiki.org/wiki/index.php/Helminthic_therapy_safety#Do_hookworms_cause_excessive_blood_loss_and_anaemia/anemia?

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    John Scott

    There is a global online community of many thousands of helminth self-treaters who are each using one or more of four specially domesticated, benign, mutualistic helminth species to treat over 160 different immune-related medical conditions, including celiac disease and other gluten-related disorders.

    Over the past two decades, the helminthic therapy community - which includes many MDs, NDs and other medical personnel, plus medical researchers and a few professors of medicine - has been developing this self-treatment and documenting their endeavours, as well as their results, on a dedicated website - the Helminthic Therapy wiki.

    Particular pages on the site that may interest readers here include the following.

    Helminthic therapy and gluten-related disorders

    Helminthic therapy research

    The history of helminthic therapy



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    Guest Keith

    Bring on the hookworms! 

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    Scott Adams

    For those interested, there is a discussion thread on this topic here:

     

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    Craig Simms

    I did the research and if anyone else does some checking you will find that Celiacs all suffer from the same symptoms as many people who are suffering from parasites such as hookworms, or tapeworms. Is it possible that people treated for worm parasites subsequently developed Celiac Disease? Think about it, the drugs used to kill worms in humans typically were designed to prevent the worm from absorbing nutrition/sugar, thus killing the worm. It is typical that one develops celiac disease once the body suffers traumatic event such as surgery, pregnancy, and/or puberty. Then offspring develop the same symptoms as relatives harboring the disease. Research now shows that once the helminth is reintroduced that the autoimmune response can be suppressed. Maybe research needs to find the correlation between the protein gluten and the components of the drugs like Mebendazole, Pyrantel, and Albendazole. As a child I was treated for tapeworms and hookworms and now a Celiac that the slightest bit of gluten and I fall apart. Every symptom of hookworm and tapeworm is identical to Celiac disease and the drugs used to rid the patient of the parasite are identical to the autoimmune response in Celiacs. All this means is some timely research to see if the use of these drugs are responsible for causing the disease we know as Celiac Disease for all those treated and their offspring.

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    trents
    40 minutes ago, Craig Simms said:

    I did the research and if anyone else does some checking you will find that Celiacs all suffer from the same symptoms as many people who are suffering from parasites such as hookworms, or tapeworms. Is it possible that people treated for worm parasites subsequently developed Celiac Disease? Think about it, the drugs used to kill worms in humans typically were designed to prevent the worm from absorbing nutrition/sugar, thus killing the worm. It is typical that one develops celiac disease once the body suffers traumatic event such as surgery, pregnancy, and/or puberty. Then offspring develop the same symptoms as relatives harboring the disease. Research now shows that once the helminth is reintroduced that the autoimmune response can be suppressed. Maybe research needs to find the correlation between the protein gluten and the components of the drugs like Mebendazole, Pyrantel, and Albendazole. As a child I was treated for tapeworms and hookworms and now a Celiac that the slightest bit of gluten and I fall apart. Every symptom of hookworm and tapeworm is identical to Celiac disease and the drugs used to rid the patient of the parasite are identical to the autoimmune response in Celiacs. All this means is some timely research to see if the use of these drugs are responsible for causing the disease we know as Celiac Disease for all those treated and their offspring.

    The problem I see with your theory is that hookworm and tapeworm infections are relatively rare in the population of developed countries in modern times. The number of people with celiac disease who have never had these worm infections and who have never been treated with the meds you mention has to be far greater than those in the celiac population who have.

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    Craig Simms

    Ah...but you missed the most important portion. I am not saying that only people who have been treated for worms are Celiacs, I am saying once treated relatives have developed genetic traits that are passed down. Think about it, and stop being so closed minded. Do some research before you type.

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    trents

    Closed minded? You're a little quick on the trigger with critical labels my friend.

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    Craig Simms
    8 minutes ago, trents said:

    The problem I see with your theory is that hookworm and tapeworm infections are relatively rare in the population of developed countries in modern times. The number of people with celiac disease who have never had these worm infections and who have never been treated with the meds you mention has to be far greater than those in the celiac population who have.

    BTW, it is not rare at all, not sure where you are getting your data but I am getting my data from CDC and NHC and more and more the disease is being recognized throughout the world. Some patients live lifetimes with parasites and Celiac Disease. I know that I was symptomatic for over 40 years before I was diagnosed, and once diagnosed I went gluten free and haven't been sick for nearly 20 years. While harboring celiac disease response I was nearly dead and after gluten-free I am unbelievably healthy. I never get sick, not even a cold.

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    Craig Simms

    FYI, people like you nearly killed my son and were probably responsible for the deaths of many of my family members. I was open minded and researched all the possibilities and came up with Celiac Disease. I had to instruct my son's gastroenterologist to check for Celiac disease. Once he was tested for IGa and TTg it was determined that he needed a duodenal biopsy, I was informed they could not perform the biopsy because he would probably bleed out. It was determined his vitamin K level was so low that he would not survive the biopsy. This was caused by his inability to absorb nutrition. They gave him vitamin "k" injections then performed the biopsy, confirming his disease. I spent the past 20 years analyzing the deaths of many family members and found that the vast majority could be directly linked to Celiac disease. If the Disease can be linked to treatment designed over 60 years ago for parasites then we can reverse the affect and save lives, this is why I offer an alternative solution. 

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  • About Me

    Jefferson Adams

    Jefferson Adams is Celiac.com's senior writer and Digital Content Director. He earned his B.A. and M.F.A. at Arizona State University. His articles, essays, poems, stories and book reviews have appeared in numerous magazines, journals, and websites, including North American Project, Antioch Review, Caliban, Mississippi Review, Slate, and more. He is the author of more than 2,500 articles on celiac disease. His university coursework includes studies in science, scientific methodology, biology, anatomy, physiology, medicine, logic, and advanced research. He previously devised health and medical content for Colgate, Dove, Pfizer, Sharecare, Walgreens, and more. Jefferson has spoken about celiac disease to the media, including an appearance on the KQED radio show Forum, and is the editor of numerous books, including "Cereal Killers" by Scott Adams and Ron Hoggan, Ed.D.

    >VIEW ALL ARTICLES BY JEFFERSON ADAMS

     


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