The Role of Mast Cells in Celiac Disease

I have both dq gene anomalies.  I also was found to have alphatrytasemia due to triple gene mutations.  My immunologist has wondered if one caused the other to activate. I also have mast cell activation syndrome.  Many in my family have celiac disease.  I hope research will find the cause and a cure for both. I am now limited to six foods. I miss my gluten-free bagel and cookies!

Great information! Dorothy Rockwell

Yesterday, I met an elderly lady at Costco.  She overheard me stating that "rolled oats" often contain gluten.  She was unaware of which products were safe and what not.  I gave her a 5 minute education regarding food labeling. She had a "worried" look on her face. How very sad to have such horrible symptomology in one's 70's. 

celiac disease/NCGS/is growing by leaps and bounds.  Newest figures I found stated a 400% disease increase over the last 50 years.  This is likely a moderate figure since many GI problems go undiagnosed or are wrongly diagnosed.  I've NEVER seen so many gluten-free frozen foods currently in the market place.  There remains too much cross-contamination at restaurants, so typically it is a smart play to order a baked sweet potato (unwrapped) with a side of butter & brown sugar plus the ALL important martini 😄 to keep oneself from crying when the waitress brings out frosted croissants, batter-dipped appetizers and pizza.

3 hours ago, Guest Laura said:

Yesterday, I met an elderly lady at Costco.  She overheard me stating that "rolled oats" often contain gluten.  She was unaware of which products were safe and what not.  I gave her a 5 minute education regarding food labeling. She had a "worried" look on her face. How very sad to have such horrible symptomology in one's 70's. 

celiac disease/NCGS/is growing by leaps and bounds.  Newest figures I found stated a 400% disease increase over the last 50 years.  This is likely a moderate figure since many GI problems go undiagnosed or are wrongly diagnosed.  I've NEVER seen so many gluten-free frozen foods currently in the market place.  There remains too much cross-contamination at restaurants, so typically it is a smart play to order a baked sweet potato (unwrapped) with a side of butter & brown sugar plus the ALL important martini 😄 to keep oneself from crying when the waitress brings out frosted croissants, batter-dipped appetizers and pizza.

Laura, how nice  you took the time to help the woman at Costco.  

To be honest, I have to wonder if celiac disease/NCGS is really growing by "leaps and bounds" or if the diagnosing of celiac itself is growing.  Healthcare has evolved in a significant number of ways in the last 50 years as have diagnostic tests.  I will also add that I believe physicians' attitudes have changed significantly and I'm willing to bet more physicians are willing to test for celiac these days than they were 50 years ago.  While this has nothing to do with celiac itself, 70 or so years ago physicians believed if one even touched a beating human heart that the patient would die, let alone consider doing surgery on the human heart.  Look where we are today when it comes to diagnosing and treating heart disease!  Many heart procedures are performed on an outpatient basis and the patient goes home the same day!

BeckyB821, I'm sure that greater medical community knowledge, awareness and better dx procedures are a major player that is driving up celiac dx rates but one has to wonder if other factors having to do with manipulation of grain genome structure and other lifestyle factors also are driving the phenomenon as well.

I do not doubt what you've posted!

Hey y'all, I am at a quandary over everything associated with Celiac Disease and Microscopic Colitis. I have 4 autoimmune diseases and left tired, exhausted and discouraged. Celiac Disease is bad enough but MC is the complicated one that has made we want to inquire about surgery in my gut. MC is doing a number on my Type 1 diabetic blood sugar.  I've heard you can heal from Celiac and in another breath, I've heard you can't. You can heal from MC but takes longer if you're older. I'm the older category.

All the night shades are double-trouble but I can eat white rice and I think wild rice might be okay. Oats is a no no! Soy makes me the sickest! I truly get sick with vomiting or diarrhea. I need to make a list of sure fire food list when going out to eat. Most times, restaurants get it right. I can't have potatoes. I eat a Caveman's diet. Probably healthier. 

Why are we suffering from Celiac and MC more than ever before? I thinks it our troubled diet of eating garbage food. It's poisoning our system and we're digging our graves with our forks. Eating out is a pain and I wish I had better news to give y'all. It's hard living with these 2 GI monsters. Dorothy Rockwell 

Welcome, Dorothy!

Have you been checked for SIBO?