Unraveling the Impact of Wheat-Based Glues on Conservation for Those with Celiac Disease

Celiac.com 05/23/2024 - For people with celiac disease, awareness extends beyond dietary concerns into unexpected areas, such as conservation and cultural heritage practices. A recent study delves into the intricate world of plant-based adhesives, particularly those derived from wheat, shedding light on their significance in conservation efforts. The research team included Rocio Prisby, Alessandra Luchini, Lance A. Liotta, and Caroline Solazzo.

Traditionally, wheat-based glues have been favored for their robust adhesive properties, making them indispensable in preserving books and paper-based artifacts. However, the adhesive's composition, especially concerning its proteome, holds crucial implications for long-term conservation outcomes.

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Distinguishing between starch paste, derived solely from starch granules, and flour paste, encompassing the entire wheat endosperm proteome, is pivotal. Flour paste, rich in gluten proteins like gliadins and glutenins, offers superior adhesive strength. Yet, this very richness poses challenges for individuals sensitive to gluten.

To dissect the proteomic makeup of these pastes, researchers developed advanced protocols involving protein extraction and identification methods. The results revealed a stark contrast in complexity between flour and starch pastes, with flour paste boasting a diverse array of proteins, including gluten and serpins.

Moreover, testing on historical bookbindings confirmed the prevalent use of flour-based glue, characterized by high levels of deamidation, particularly impacting glutamine residues. This finding underscores the importance of understanding the adhesive's stability and solubility over time, especially in the context of conservation efforts.

As individuals with celiac disease navigate environments where wheat-based glues may be prevalent, such insights offer valuable considerations for preserving cultural artifacts without compromising health. Ultimately, this research highlights the interdisciplinary nature of celiac disease awareness and its impact on diverse fields beyond the realm of food.

Read more in the Journal of Proteome Research