Jump to content
This site uses cookies. Continued use is acceptance of our Terms of Use and Privacy Policy. More Info... ×
  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.




  • Celiac.com Sponsor (A1):



    Celiac.com Sponsor (A1-M):


  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate
  • Jefferson Adams
    Jefferson Adams

    Unvaccinated Celiac Patients Face Higher Pneumonia Risk

    Reviewed and edited by a celiac disease expert.
    Unvaccinated Celiac Patients Face Higher Pneumonia Risk - Vaccines can help protect celiac disease patients from pneumonia. Photo: CC--Helge V. Keitel
    Caption: Vaccines can help protect celiac disease patients from pneumonia. Photo: CC--Helge V. Keitel

    Celiac.com 06/22/2016 - Doctors generally recommend that celiac disease patients receive pneumococcal vaccination, but little has been done to quantify risk levels.

    A team of researchers recently set out to quantify the risk of community-acquired pneumonia among patients with celiac disease, assessing whether vaccination against streptococcal pneumonia modified this risk. The research team included F. Zingone, A. Abdul Sultan, C. J. Crooks, L. J. Tata, C. Ciacci & J. West. They are variously affiliated with the Division of Epidemiology and PublicHealth, University of Nottingham, CityHospital, Nottingham, UK, and with the Coeliac center within the Department of Medicine and Surgery at the University of Salerno in Salerno, Italy.

    Celiac.com Sponsor (A12):
    Their team identified all patients with celiac disease within the Clinical Practice Research Datalink linked with English Hospital Episodes Statistics between April 1997 and March 2011 and up to 10 controls per patient with celiac disease frequency matched in 10-year age bands.

    They calculated absolute rates of community-acquired pneumonia for patients with celiac disease compared to controls stratified by vaccination status and time of diagnosis using Cox regression in terms of adjusted hazard ratios (HR). They found 1,864 first community-acquired pneumonia events among the 101,755 control patients, and 179 among the 9,803 celiac patients.

    Overall, absolute rates of pneumonia were similar, with celiac patients at 3.42, and control subjects at 3.12 per 1000 person-years respectively (HR 1.07, 95% CI 0.91–1.24). However, they found a 28% increased risk of pneumonia in unvaccinated celiac disease subjects compared to unvaccinated control subjects (HR 1.28, 95% CI 1.02–1.60).

    Interestingly, this increased risk was limited to those younger than 65, was highest around the time of diagnosis and was maintained for more than 5 years after diagnosis. Only 26.6% underwent vaccination after their celiac disease diagnosis.

    Unvaccinated celiac patients under the age of 65 have an excess risk of community-acquired pneumonia that was not seen in vaccinated celiac patients. More patients with celiac disease need to be vaccinated to protect them from pneumonia.

    Source:

    • Open Original Shared Link


    User Feedback

    Recommended Comments

    There are no comments to display.



    Create an account or sign in to comment

    You need to be a member in order to leave a comment

    Create an account

    Sign up for a new account in our community. It's easy!

    Register a new account

    Sign in

    Already have an account? Sign in here.

    Sign In Now

  • Get Celiac.com Updates:
    Support Celiac.com:
    Donate
  • About Me

    Jefferson Adams

    Jefferson Adams is Celiac.com's senior writer and Digital Content Director. He earned his B.A. and M.F.A. at Arizona State University. His articles, essays, poems, stories and book reviews have appeared in numerous magazines, journals, and websites, including North American Project, Antioch Review, Caliban, Mississippi Review, Slate, and more. He is the author of more than 2,500 articles on celiac disease. His university coursework includes studies in science, scientific methodology, biology, anatomy, physiology, medicine, logic, and advanced research. He previously devised health and medical content for Colgate, Dove, Pfizer, Sharecare, Walgreens, and more. Jefferson has spoken about celiac disease to the media, including an appearance on the KQED radio show Forum, and is the editor of numerous books, including "Cereal Killers" by Scott Adams and Ron Hoggan, Ed.D.

    >VIEW ALL ARTICLES BY JEFFERSON ADAMS

     


  • Celiac.com Sponsor (A17):
    Celiac.com Sponsor (A17):





    Celiac.com Sponsors (A17-M):




  • Related Articles

    Jefferson Adams
    Celiac.com 01/14/2013 - Sweden has seen a sharp rise in cases of celiac disease in children under two years of age. A research team recently studied the possible connection between early infections and celiac disease, along with their possible role in the explosion of celiac cases in Swedish children.
    The research team included Anna Myléus, Olle Hernell, Leif Gothefors, Marie-Louise Hammarström, Lars-Åke Persson, Hans Stenlund and Anneli Ivarsson.
    They are affiliated with the Epidemiology and Global Health, Department of Public Health and Clinical Medicine at Umeå University, Pediatrics unit of the Department of Clinical Sciences at Umeå University, the Immunology unit of the Department of Clinical Microbiology at Umeå University in Umeå, Sweden, and with the International Matern...


    Jefferson Adams
    Hepatitis B Vaccine and Boosters Less Effective in People With Celiac Disease
    A team of researchers recently took a look at how well the hepatitis B vaccine protected people with celiac disease over time. Specifically, they evaluated what is called long-term antibody persistence and immune memory to hepatitis B virus in adult celiac patients vaccinated as adolescents.
    The research team included F. Zingone, F. Morisco, A. Zanetti, L. Romanò, G. Portella, P. Capone, P. Andreozzi, R. Tortora, and C.Ciacci. They are affiliated with the Department of Clinical and Experimental Medicine of Federico II University of Naples in Italy.
    They set out to investigate the anti-HBs antibody persistence and immune memory to hepatitis B virus in adult celiacs vaccinated as adolescents, along with the effects of a booster administration in non-protected individuals. <...>

    Jefferson Adams
    Celiac.com 07/27/2015 - First-degree relatives of individuals with celiac disease are at increased risk for this disorder, but little is known about their risk for other autoimmune diseases.
    A research team recently set out to assess the risk of non-celiac autoimmune disease in first-degree relatives and spouses of people with celiac disease.
    The research team included Louise Emilsson, Cisca Wijmenga, Joseph A. Murray, and Jonas F. Ludvigsson. They are variously affiliated with the Primary Care Research Unit, Vårdcentralen Värmlands Nysäter, Värmland County, Sweden, the Department of Health Management and Health Economy, Institute of Health and Society, University of Oslo, Oslo, Norway, the Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, Th...


    Jefferson Adams
    Celiac.com 08/17/2015 - In an interesting update, researcher Giuseppe Mazzarella, of the Immuno-Morphology Lab at the Institute of Food Sciences of the National Council Research in Avellino, Italy recently set out to examine the role of effector and suppressor T cells in celiac.
    Celiac disease is a T-cell-mediated immune disorder in which gliadin-derived peptides activate lamina propria effector CD4+ T cells.
    This activation triggers the release of cytokines, compatible with a Th1-like pattern, which play a crucial role in the development of celiac disease, and which control many aspects of the inflammatory immune response.
    Previous studies revealed that a novel subset of effector T cells, marked by expression of high levels of IL-17A, termed Th17 cells, plays a key role in celiac...


  • Recent Activity

    1. - Wheatwacked replied to Kathleen JJ's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
      6

      Options - 7 year old boy - Helicobacter pylori and serology

    2. - Wheatwacked replied to MHavoc's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
      1

      On the cusp of facing a new life of managing a life with Celiac Disease

    3. - MHavoc posted a topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
      1

      On the cusp of facing a new life of managing a life with Celiac Disease

    4. - Vozzyv posted a topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
      0

      Weird Symptoms

    5. - cristiana replied to Kathleen JJ's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
      6

      Options - 7 year old boy - Helicobacter pylori and serology


  • Celiac.com Sponsor (A19):



  • Member Statistics

    • Total Members
      126,073
    • Most Online (within 30 mins)
      7,748

    Steph4213
    Newest Member
    Steph4213
    Joined

  • Celiac.com Sponsor (A20):


  • Forum Statistics

    • Total Topics
      120.9k
    • Total Posts
      69.2k

  • Celiac.com Sponsor (A22):





  • Celiac.com Sponsor (A21):



  • Popular Now

    • Kathleen JJ
    • Captain173
      10
    • jjiillee
      7
    • Kristina12
      7
    • StaciField
  • Popular Articles

    • Scott Adams
    • Scott Adams
    • Scott Adams
    • Scott Adams
    • Scott Adams
  • Upcoming Events

×
×
  • Create New...