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Celiac Disease Pre-Diagnosis, Testing & Symptoms
If you haven't yet been diagnosed this is the place you can discuss your symptoms and any test results that may indicate that you might have the disease.
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Recent Activity
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- trents replied to TexasCeliacNewbie's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms1Just got Celiac blood test results back and they seem crazy high!
Welcome to the forum, @TexasCeliacNewbie! The test results you posted strongly point to celiac disease. It is likely that your physician will want to perform an endoscopy with biopsy of the small bowel lining to confirm the results of the celiac antibody bloodwork results you just posted. It is important that you not cut back on gluten consumption until... -
- TexasCeliacNewbie posted a topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms1Just got Celiac blood test results back and they seem crazy high!
Hi, I have been having a lot of back pain and gut issues for 8 weeks or so. I saw the GI on Monday and my results just came in from the lab. Some of these number are high and off the little chart from the lab. I am reading this correctly that I most likely have Celiac, right??? It would explain a lot of things for me that otherwise are worrying me that... -
- trents replied to TerryinCO's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms18
New Guy Here...
So, I would assume it means that if the risk of developing celiac disease in the general population is 1%, people with the DQ2 gene have a 10% risk of developing celiac disease. So, have you or your physician concluded that you have celiac disease? -
- TerryinCO replied to TerryinCO's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms18New Guy Here...
Here's the test result I was refering to. I may not be understanding this correctly. -
- trents replied to TerryinCO's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms18
New Guy Here...
Thanks for the update @TerryinCO! Would you elaborate what you mean when you say your genetic tests show that you are "10x higher" for developing celiac disease? 10x higher than what? There are two main genes, HLA-DQ2 and HLA-DQ8, that have been identified as providing the potential for developing celiac disease. Since 40% of the population carries one...
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Welcome to the forum, @TexasCeliacNewbie! The test results you posted strongly point to celiac disease. It is likely that your physician will want to perform an endoscopy with biopsy of the small bowel lining to confirm the results of the celiac antibody bloodwork results you just posted. It is important that you not cut back on gluten consumption until the endoscopy/biopsy is complete, assuming, that is, one is forthcoming. Can you post the actual reference ranges used by the lab for the tests to determine positive/negative/normal/high/low? Scales used by these labs are different from one place to the other so the raw numbers don't mean much without the scale used by the lab. There aren't industry standards for this. By the way, you probably won't be able to edit the original post so please post the extra info in new post. May we ask about the cancer you mentioned? There are some things that can elevate the antibody test scores, at least mildly, besides celiac disease.
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By TexasCeliacNewbie · Posted
Hi, I have been having a lot of back pain and gut issues for 8 weeks or so. I saw the GI on Monday and my results just came in from the lab. Some of these number are high and off the little chart from the lab. I am reading this correctly that I most likely have Celiac, right??? It would explain a lot of things for me that otherwise are worrying me that my previous cancer is recurring. Thank you for all of your expertise in this area! Immunoglobulin A, Qn, Serum 140 (normal) Deamidated Gliadin Abs, IgA 256 (High) Deamidated Gliadin Abs, IgG 65 (High) t-Transglutaminase (tTG) IgA 31 (High) t-Transglutaminase (tTG) IgG 10 (High) -
So, I would assume it means that if the risk of developing celiac disease in the general population is 1%, people with the DQ2 gene have a 10% risk of developing celiac disease. So, have you or your physician concluded that you have celiac disease?
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Here's the test result I was refering to. I may not be understanding this correctly.
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Thanks for the update @TerryinCO! Would you elaborate what you mean when you say your genetic tests show that you are "10x higher" for developing celiac disease? 10x higher than what? There are two main genes, HLA-DQ2 and HLA-DQ8, that have been identified as providing the potential for developing celiac disease. Since 40% of the population carries one or both of these genes but only 1% of the population actually develops celiac disease, the genetic test cannot be used to diagnose celiac disease, simply to establish the potential for developing it. Gene testing is usually done to rule out celiac disease vs. NCGS (Non Celiac Gluten Sensitivity). In other words, if gluten consumption is definitely causing someone problems but they don't have the genetic potential for developing celiac disease then the diagnosis would be NCGS. We also know that having both DQ2 and DQ8 puts one at higher risk for developing celiac disease than having just one or the other. But I'm not sure I've ever seen it quantified as in "10x higher". Not sure what you mean by this.
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