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- knitty kitty replied to Kipman's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms6Indeterminate transglutaminase iga
@Kipman, Ask for a genetic test to determine if you have any of the known genes for Celiac Disease. Anemia, Thiamine deficiency and diabetes can each cause false negatives and low IgA. You may want to investigate these further with your doctor. Celiac Disease can occur with Ehlers-Danlos Syndrome, another genetic autoimmune disease. Ehlers... -
- knitty kitty replied to Travel Celiac's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms2
Test says no, but body says Yes?
Welcome to the forum, @Travel Celiac! You have to be consuming gluten for your body to trigger the autoimmune response and produce anti-gluten antibodies. If you're not consuming gluten, the autoimmune response is not triggered and you won't produce anti-gluten antibodies. Celiac Disease is genetic. Your genes don't change. You will always have... -
- trents replied to Kipman's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms6Indeterminate transglutaminase iga
I've never heard it said that celiac disease is a connective tissue disease. It is an autoimmune disorder that (classically) attacks the lining of the small bowel but we now know it can manifest in other body systems. It is also true that autoimmune disorders tend to cluster. That is, when you have one you often develop others. -
- Kipman replied to Kipman's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms6Indeterminate transglutaminase iga
I did for a week, though that was 4 weeks before I had the test done. The doctor told me the lab rang her and said they hadn't seen results like it in their lab. Them being nearly all indeterminate that is. I also tested positive for a multiple connective tissue disease but when they did further testing it was all indeterminate too (I've only just... -
- trents replied to Kipman's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms6
Indeterminate transglutaminase iga
So, it sounds like you may have already been avoiding gluten before the blood draw was done for the antibody testing. Is this correct?
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By knitty kitty · Posted
@Kipman, Ask for a genetic test to determine if you have any of the known genes for Celiac Disease. Anemia, Thiamine deficiency and diabetes can each cause false negatives and low IgA. You may want to investigate these further with your doctor. Celiac Disease can occur with Ehlers-Danlos Syndrome, another genetic autoimmune disease. Ehlers-Danlos is a connective tissue disease frequently seen in people who are double jointed or have stretchy skin. This stretchy-ness can affect the digestive system. https://pubmed.ncbi.nlm.nih.gov/27321543/ -
By knitty kitty · Posted
Welcome to the forum, @Travel Celiac! You have to be consuming gluten for your body to trigger the autoimmune response and produce anti-gluten antibodies. If you're not consuming gluten, the autoimmune response is not triggered and you won't produce anti-gluten antibodies. Celiac Disease is genetic. Your genes don't change. You will always have the Celiac genes whether you eat gluten or not. Your negative tTg-IgA shows that you are successfully keeping gluten out of your diet. You are doing very well on that point, but you still are Celiac. Be proud of your accomplishment! -
I've never heard it said that celiac disease is a connective tissue disease. It is an autoimmune disorder that (classically) attacks the lining of the small bowel but we now know it can manifest in other body systems. It is also true that autoimmune disorders tend to cluster. That is, when you have one you often develop others.
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I did for a week, though that was 4 weeks before I had the test done. The doctor told me the lab rang her and said they hadn't seen results like it in their lab. Them being nearly all indeterminate that is. I also tested positive for a multiple connective tissue disease but when they did further testing it was all indeterminate too (I've only just realised that celuac is a connective tissue disease)
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So, it sounds like you may have already been avoiding gluten before the blood draw was done for the antibody testing. Is this correct?
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