Jump to content
This site uses cookies. Continued use is acceptance of our Terms of Use and Privacy Policy. More Info... ×

  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.



  • Celiac.com Sponsor (A1):

    Celiac.com Sponsor (A1-M):

  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Mthfr Gene Mutation

seraphim

By seraphim
in Related Issues & Disorders

Recommended Posts

seraphim Contributor
seraphim
Posted

My doctor is giving me this gene test...from what I read it can affect the bodies ability to detox...detox what exactly i'm not sure but I may have a problem with salicylates and I did read chemical sensitivities can happen as a result of this. I don't know if I completely understand the whole thing yet only that they often give methyl b12....does this help with methylation? Does it detox whatever is going on in your body? A little confused. Either way..anyone else have this gene mutation?

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


1desperateladysaved Proficient
1desperateladysaved
Posted

Methyl B12, are you talking about vitamin B?

seraphim Contributor
seraphim
Posted
  • Author

Yes a specific kind of b12 because it bypasses a certain stage of conversion that people with this mutation can't do.

frieze Community Regular
frieze
Posted

methylcobalamin, that is B12 that is already methylated, which is the usable form.  If you take the cyano- variety, the body needs break the cyano- molecule off, ad then methylate the cobalamin.  most persons can do that, but those with that particular gene mutation can't.

seraphim Contributor
seraphim
Posted
  • Author

Right. From what I understand the defective gene is actually very common...about 40% of the population is suppose to have it.

Mad Engineer Newbie
Mad Engineer
Posted

I've been reading up on it. Not sure how much is real science and how much is interweb psudoscience. It sounds like many people with this issue has had success with the Methy version of B-12 along with l-methylfolate as part of their treatment "protocol", along with a bunch of other vitamins and minerals that are of course linked directly to websites that sell them. Taking those two above vitamins (available from any health supplement store) did help me with my fatigue and mental fog... not  totally but maybe 50-75%. The biggest thing is that it doesn't take me an hour to get out of bed anymore. I actually got out of bed before my alarm! which has never happened in my life!

 

anyway.. There seems to be quite a few overlaping symptoms between mthfr gene mutation and gluten intolerance.. and a common recommendation on mthfr treatment is to actually eliminate gluten and casein. I wonder if there is some kind of link between the two????? 

seraphim Contributor
seraphim
Posted
  • Author

Wouldn't shock me. The defect can lead to any number of issues. A friend of mine has it and has blood clotting issues. It tends to affect everyone differently.

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


Archived

This topic is now archived and is closed to further replies.

Go to topic listing

  • Get Celiac.com Updates:
    Support Celiac.com:
    Join eNewsletter
    Donate
  • Celiac.com Sponsor (A17):
    Celiac.com Sponsor (A17):



    Celiac.com Sponsors (A17-M):



  • Recent Activity

    1. Celiacandme
      - Celiacandme replied to Kwinkle's topic in Coping with Celiac Disease
      4

      I’m so confused…

      You might also be sensitive to other things while you are healing. Dairy, for example. It won't harm you from a celiac standpoint but is inflammatory and could be bothering you. Have you been keeping a food & symptom journal? Might be worth it for a week to see if you notice something you are eating prior to the times you feel your worst. I hope you start...
    2. lmemsm
      - lmemsm replied to jasoncrest's topic in Gluten-Free Recipes & Cooking Tips
      4

      Recipe Apps?

      Someone recently recommended Superfoods for looking up recipes free of allergens or intolerances. It's a web site but there's also an app.
    3. lmemsm
      - lmemsm posted a topic in Gluten-Free Foods, Products, Shopping & Medications
      0

      food app

      Open Food Facts is a free food database: https://world.openfoodfacts.org/discover There's an app to access it which is also free (with no in app commercials). You can use it to look up information about foods such as ingredients, Nova score (to help avoid ultra processed foods), environmental impact and nutritional scores, allergy related information and...
    4. lmemsm
      - lmemsm replied to trsprecker's topic in Coping with Celiac Disease
      5

      OTC pain reliever that are gluten-free and corn free??

      You could try white willow bark, but make sure it's in a safe dosage range. Herbs aren't regulated the way prescriptions are. White willow bark works a lot like aspirin but is often milder on the stomach. I used to use Nature's Way white willow bark. I was told it was corn free at that time. Double check with the manufacturer to make sure it's free of...
    5. Scott Adams
      - Scott Adams replied to Kwinkle's topic in Coping with Celiac Disease
      4

      I’m so confused…

      Be sure to bring this up with your doctor, as there is always the possibility that you've got other issues besides celiac disease.
  • Celiac.com Sponsor (A19):


  • Member Statistics

    • Total Members
      127,274
    • Most Online (within 30 mins)
      7,748
    CLMILAN
    Newest Member
    CLMILAN
    Joined
  • Celiac.com Sponsor (A20):

  • Forum Statistics

    • Total Topics
      121k
    • Total Posts
      70.1k
  • Celiac.com Sponsor (A22):



  • Celiac.com Sponsor (A21):


  • Upcoming Events

  • Posts

    • Celiacandme
      I’m so confused…

      By Celiacandme · Posted

      You might also be sensitive to other things while you are healing. Dairy, for example. It won't harm you from a celiac standpoint but is inflammatory and could be bothering you. Have you been keeping a food & symptom journal? Might be worth it for a week to see if you notice something you are eating prior to the times you feel your worst. I hope you start feeling better soon. 
    • lmemsm
      Recipe Apps?

      By lmemsm · Posted

      Someone recently recommended Superfoods for looking up recipes free of allergens or intolerances.  It's a web site but there's also an app.
    • lmemsm
      food app

      By lmemsm · Posted

      Open Food Facts is a free food database: https://world.openfoodfacts.org/discover  There's an app to access it which is also free (with no in app commercials).   You can use it to look up information about foods such as ingredients, Nova score (to help avoid ultra processed foods), environmental impact and nutritional scores, allergy related information and more.  It can scan a product's barcodes and bring up relevant information about that product.  The project relies on volunteers to share information about products.  We can add information on our favorite gluten free products to share with each other.  It has several gluten free items in the database already:  https://world.openfoodfacts.org/cgi/search.pl?search_terms=gluten+free&search_simple=1&action=process  I think it could make a great tool for people with celiac. 
    • lmemsm
      OTC pain reliever that are gluten-free and corn free??

      By lmemsm · Posted

      You could try white willow bark, but make sure it's in a safe dosage range.  Herbs aren't regulated the way prescriptions are.  White willow bark works a lot like aspirin but is often milder on the stomach.  I used to use Nature's Way white willow bark.  I was told it was corn free at that time.  Double check with the manufacturer to make sure it's free of any of any allergens you're concerned with.
    • Scott Adams
      I’m so confused…

      By Scott Adams · Posted

      Be sure to bring this up with your doctor, as there is always the possibility that you've got other issues besides celiac disease.
×
×
  • Create New...