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Can Someone Help Me With My Test Results?

melisadki

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melisadki Explorer
melisadki
Posted

I just got my blood test results back. I dont even understand what they mean. Can someone tell me if this test is negative. Also if it is should I assume I am not Celiac and just gluten intolerant because my enterolab results were positive. I am so confused. I made an appt. with a GI doctor for next week to see if I can have a biopsy or something to see what is causing all of my symptoms.

Thanks so much. :)

Just click on the link below because I cant figure out how to get the picture in here.<_<

Here is the lab results.

http://i3.photobucket.com/albums/y70/melpo...tsCeliac001.webp

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Rachel--24 Collaborator
Rachel--24
Posted

From what I can tell your results are negative for Celiac. The only way to know for sure (since you were positive with Enterolab) would be to go on the diet 100% for at least a few weeks to see if there is a difference in symptoms. If you plan on having the biopsy wait till after its done to go on the diet.

melisadki Explorer
melisadki
Posted
  • Author

I just cant quite figure out why it is negative and enterolab was a definate positive although I only had the Iga test done through them. The results where 19 gliadian Iga (>10). I see a GI doctor next week to find out if not celiac what is causing so much diarhea and food malabsorbtion. Not to be gross but I can actually identify what is in my Poo (sorry TMI) along with the fat rings in my Poo. Everyday too! It is getting so annoying. So I will wait to go gluten-free still :rolleyes: I just know it is my problem celiac or no celiac. If not maybe I am just crazy like they have been telling me all along.. :o:angry:

I also thinking when I get a few extra bucks of ordering the saliva gene test through enterolab: seems that would be very accurate to say whether or not you would be more likely to ever develop Celiac or other autoimmune things.

I swear if it wasnt for the negative blood work I would think I definetly had Celiac. When I read the symptoms I match around 90 percent of them including depression and infertilty etc...etc.. :unsure:

Rachel thank you so much for helping. I am lost without this board.. :blink:

ravenwoodglass Mentor
ravenwoodglass
Posted
I just cant quite figure out why it is negative and enterolab was a definate positive although I only had the Iga test done through them.  The results where 19 gliadian Iga (>10).  I see a GI doctor next week to find out if not celiac what is causing so much diarhea and food malabsorbtion.  Not to be gross but I can actually identify what is in my Poo (sorry TMI) along with the fat rings in my Poo.  Everyday too! It is getting so annoying.  So I will wait to go gluten-free still :rolleyes: I just know it is my problem celiac or no celiac.  If not maybe I am just crazy like they have been telling me all along.. :o  :angry:

I also thinking when I get a few extra bucks of ordering the saliva gene test through enterolab: seems that would be very accurate to say whether or not you would be more likely to ever develop Celiac or other autoimmune things.

I swear if it wasnt for the negative blood work I would think I definetly had Celiac.  When I read the symptoms I match around 90 percent of them including depression and infertilty etc...etc.. :unsure:

Rachel thank you so much for helping.  I am lost without this board.. :blink:

<{POST_SNAPBACK}>

Just a note, if I had only gone off blood work I would still be eating gluten and still be sick. You are doing the right thing by continuing to pursue this with your doctor but don't be afraid to give the diet a try before you say for sure that gluten isn't a problem.

melisadki Explorer
melisadki
Posted
  • Author

Thanks for that recommendation Ravenwood.. :)

Rachel--24 Collaborator
Rachel--24
Posted

Yes, Ravenwood is right. If I went off my bloodtests alone I'd still be sick too. I had my bloodtests October last year and they were negative so I kept eating gluten until I could no longer get out of bed at all. I had the same problem as you with my food coming out undigested and I lost 25 lbs.

melisadki Explorer
melisadki
Posted
  • Author

I really see why this disease is so underdiagnosed now. :( If I am just technically Gluten Intolerant can this still cause all of the symptoms of Celiac Disease without actually having Celiac Disease. In other words is one just the bad as the other as far as attacking your body all over if untreated? ;)

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Rachel--24 Collaborator
Rachel--24
Posted

Yes, it can be just as bad w/out being Celiac. Have you read Dangerous Grains? It explains alot.

melisadki Explorer
melisadki
Posted
  • Author

I plan on reading it soon my sister is going to get it at her bookstore this week. I hear it has alot on this stuff. :)

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    • Scott Adams
      How many grams is there in one slice of wheat bread?

      By Scott Adams · Posted

      The first set of results show two positive results for celiac disease, so at the very least it looks like you could have it, or at the least NCGS.   Approximately 10x more people have non-celiac gluten sensitivity than have celiac disease, but there isn’t yet a test for NCGS. If your symptoms go away on a gluten-free diet it would likely signal NCGS.      
    • Scott Adams
      Confused with test results

      By Scott Adams · Posted

      Elevated tissue transglutaminase IgA (tTG-IgA) levels are highly specific for celiac disease, and they are a key biomarker used in its diagnosis. However, there are some rare instances where elevated tTG-IgA levels have been reported in conditions other than celiac disease. While these cases are not common, they have been documented in the literature. Below are some examples and references to studies or reviews that discuss these scenarios:  1. Non-Celiac Gluten Sensitivity (NCGS)    - NCGS typically does not cause elevated tTG-IgA levels, as it is not an autoimmune condition. However, some individuals with NCGS may have mild elevations in tTG-IgA due to intestinal inflammation or other factors, though this is not well-documented in large studies.    - Reference: Catassi, C., et al. (2013). *Non-Celiac Gluten Sensitivity: The New Frontier of Gluten-Related Disorders*. Nutrients, 5(10), 3839–3853. [DOI:10.3390/nu5103839](https://doi.org/10.3390/nu5103839)  2. Autoimmune Diseases    - Elevated tTG-IgA levels have been reported in other autoimmune conditions, such as type 1 diabetes, autoimmune hepatitis, and systemic lupus erythematosus (SLE). This is thought to be due to cross-reactivity or polyautoimmunity.    - Reference: Sblattero, D., et al. (2000). *The Role of Anti-Tissue Transglutaminase in the Diagnosis and Management of Celiac Disease*. Autoimmunity Reviews, 1(3), 129–135. [DOI:10.1016/S1568-9972(01)00022-3](https://doi.org/10.1016/S1568-9972(01)00022-3)  3. Chronic Liver Disease    - Conditions like chronic hepatitis or cirrhosis can sometimes lead to elevated tTG-IgA levels, possibly due to increased intestinal permeability or immune dysregulation.    - Reference: Vecchi, M., et al. (2003). *High Prevalence of Celiac Disease in Patients with Chronic Liver Disease: A Role for Gluten-Free Diet?* Gastroenterology, 125(5), 1522–1523. [DOI:10.1016/j.gastro.2003.08.031](https://doi.org/10.1016/j.gastro.2003.08.031)  4. Inflammatory Bowel Disease (IBD)    - Some patients with Crohn’s disease or ulcerative colitis may have elevated tTG-IgA levels due to intestinal inflammation and damage, though this is not common.    - Reference: Walker-Smith, J. A., et al. (1990). *Celiac Disease and Inflammatory Bowel Disease*. Journal of Pediatric Gastroenterology and Nutrition, 10(3), 389–391. [DOI:10.1097/00005176-199004000-00020](https://doi.org/10.1097/00005176-199004000-00020)  5. Infections and Parasites    - While infections (e.g., giardiasis) are more commonly associated with false-positive tTG-IgA results, chronic infections or parasitic infestations can sometimes lead to elevated levels due to mucosal damage.    - Reference: Rostami, K., et al. (1999). *The Role of Infections in Celiac Disease*. European Journal of Gastroenterology & Hepatology, 11(11), 1255–1258. [DOI:10.1097/00042737-199911000-00010](https://doi.org/10.1097/00042737-199911000-00010)  6. Cardiac Conditions    - Rarely, heart failure or severe cardiovascular disease has been associated with elevated tTG-IgA levels, possibly due to gut ischemia and increased intestinal permeability.    - Reference: Ludvigsson, J. F., et al. (2007). *Celiac Disease and Risk of Cardiovascular Disease: A Population-Based Cohort Study*. American Heart Journal, 153(6), 972–976. [DOI:10.1016/j.ahj.2007.03.019](https://doi.org/10.1016/j.ahj.2007.03.019)  Key Points: - Elevated tTG-IgA levels are highly specific for celiac disease, and in most cases, a positive result strongly suggests celiac disease. - Other conditions causing elevated tTG-IgA are rare and often accompanied by additional clinical findings. - If celiac disease is suspected, further testing (e.g., endoscopy with biopsy) is typically required for confirmation. If you’re looking for more specific studies, I recommend searching PubMed or other medical databases using terms like "elevated tTG-IgA non-celiac" or "tTG-IgA in non-celiac conditions." Let me know if you’d like help with that!
    • MaryMJ
      Water filters and gluten

      By MaryMJ · Posted

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    • trents
      What should I do with these test results?

      By trents · Posted

      I agree. Doesn't look like you have celiac disease. Your elevated DGP-IGG must be due to something else. And it was within normal at that after your gluten challenge so it is erratic and doesn't seem to be tied to gluten consumption.
    • Jack Common
      How many grams is there in one slice of wheat bread?

      By Jack Common · Posted

      Hello! I want to share my situation. I had symptoms like some food intolerance, diarrhea, bloating, belching one year ago. I thought I could have celiac disease so I did the blood tests. The results were ambiguous for me so I saw the doctor and he said I needed to do tests to check whether I had any parasites as well. It turned out I had giardiasis. After treating it my symptoms didn't disappear immediately. And I decided to start a gluten free diet despite my doctor said I didn't have it. After some time symptoms disappeared but that time it wasn't unclear whether I'd had them because of eliminating gluten or that parasite. The symptoms for both are very similar. Giardiasis also damages the small intestine. The only way to check this was to start eating bread again as I thought. Now about my results.   These are my first test results (almost a year ago) when I had symptoms: The Tissue Transglutaminase IgA antibody - 0.5 U/ml (for the lab I did the tests 0.0 - 3.0 is normal) The Tissue Transglutaminase IgG antibody - 6.6 U/ml (for the lab I did the tests 0.0 - 3.0 is normal) Immunoglobulin A - 1.91 g/l (for the lab I did the tests 0.7 to 4 g/l is normal) IgA Endomysial antibody (EMA) - < 1:10 titer (for the lab I did the tests < 1:10 titer is normal) IgG Endomysial antibody (EMA) - < 1:10 titer (for the lab I did the tests < 1:10 titer is normal) Deamidated gliadin peptide IgA - 0.3 U/ml (for the lab I did the tests 0.0 - 6.0 is normal) Deamidated gliadin peptide IgG - 46.1 U/ml (for the lab I did the tests 0.0 - 6.0 is normal)   Then I didn't eat gluten for six months. Symptoms disappeared. And I started a gluten challenge. Before the challenge I did some tests. My results: The Tissue Transglutaminase IgG antibody - 0.5 U/ml (for the lab I did the tests < 20 U/ml is normal)) Deamidated gliadin peptide IgG - 28 U/ml (for the lab I did the tests < 20 U/ml is normal)   During the challenge I ate 6 slices of wheat bread. After the challenge my results are: The Tissue Transglutaminase IgA antibody - 2.0 U/ml (for the lab I did the tests < 20 U/ml is normal) The Tissue Transglutaminase IgG antibody - 2.0 U/ml (for the lab I did the tests < 20 U/ml is normal) Immunoglobulin A - 1.31 g/l (for the lab I did the tests 0.7 to 4 g/l is normal) Deamidated gliadin peptide IgA - 2.0 U/ml (for the lab I did the tests < 20 U/ml is normal) Deamidated gliadin peptide IgG - 2.13 U/ml (for the lab I did the tests < 20 U/ml is normal)   To be sure I continued consuming gluten. I ate a lot each day. Two months after I did the tests again. My results I got today are: The Tissue Transglutaminase IgA antibody - 0.7 U/ml (for the lab I did the tests < 20 U/ml is normal) Immunoglobulin A - 1.62 g/l (for the lab I did the tests 0.7 to 4 g/l is normal) Deamidated gliadin peptide IgG - 25.6 U/ml (for the lab I did the tests < 20 U/ml is normal)   Nowadays I didn't have any symptoms except tiredness but I think it's just work. I think it was this parasite because two years ago, for example, and before I didn't have these symptoms and I always ate gluten food. But I'm still not sure especially because the Deamidated gliadin peptide IgG results are sometimes high. What do you think? @Scott Adams
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