Jump to content
  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.




  • Celiac.com Sponsor (A1):



    Celiac.com Sponsor (A1-M):


  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

What Are Normal Iga And Igg Levels?


heliosue

Recommended Posts

heliosue Apprentice

Still trying to pin down whether I have Celiac Disease or Non-Celiac Gluten Intolerence. Based on a suggestion from a forum member, I just had my IGA total serum test and won't know the results for awhile.  But.. I have a question about normal levels based on the descriptions that I have read in a few online articles. The articles offer several possible outcomes if the total IGA is low, and the rest of the antibody tests are "normal".  Where can I go to find out what is "normal" on these other tests.  Is it "no antibodies detected"? Is it any result that falls below the upper range?  I have a feeling that the result of this latest test is going to continue to place me in the inconclusive category, as the ONLY positive on the previous tests was the TTG Antibody, IGG, which was at 10 (high according to the report). (Does anyone know what the high range is for that TTG, IGG test?  Is it 10 out of 100? or 10 out of 1000?) The previous tests were taken when I was eating a partially gluten free diet. (I hadn't been told that a Celiac/Gluten panel was going to done as part of my broader annual bloodwork), so I'm not at all sure those negative results mean much.  I feel so much better now that I'm gluten-free, that I really don't know if I can make myself go back to eating gluten in order to verify the previous test results or even go the biopsy route.


Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):



Celiac.com Sponsor (A8-M):



Brit1612 Apprentice

I think each lab can be different, but for example, my son's ttg igg was "slightly elevated" the first time he had it done and it was a 7, the second time it was a 15 (clear positive) and the last time is was .5 (negative).  The range for all of these labs was <6 was considered "normal", Between 6 and 8 was like a mild positive and >8 was positive.  So if your lab was the same your result would have been a clear positive for that test.  Just so you know, my son had that test positive with others negative and we just had a negative biopsy.  He also came back negative for the same test (while consuming gluten).  We are being told that it could have been some kind of infection causing the positive, and now that it is negative we are being told not to worry but to trust the results we are getting now (including the biopsy).  Just thought I would share.

nvsmom Community Regular

Yes.  Lab normal ranges can vary quite a bit.  I've seen from 0-4 up to 0-20.  My lab range was the 0-20, and everything above a 20 was considered high.  If you have 19.8, you are not a celiac but 20.2 probably is.   :rolleyes:   My result was stated at greater than 200 so I have no idea what it actually was - could have been 201 or 1000.  ;)

 

The normal range usually starts at 0 though.  If your 10 was high, your upper normal limit was probably 4, 5, or 6.  Perhaps you can request a copy of the lab report and then you'll know for sure.

 

If you want to stay gluten-free yet want to verify your diagnosis, try retesting after 6 months.  If your result has come down, it probably was celiac disease.... A positive test result means it is probably celiac disease anyways.  Those tests are pretty specific to celiac disease. This report shows that the specificity of a positive for celiac disease for the tTG IgG (SP) is about 95%. Open Original Shared Link

 

Best wishes.

heliosue Apprentice

I think each lab can be different, but for example, my son's ttg igg was "slightly elevated" the first time he had it done and it was a 7, the second time it was a 15 (clear positive) and the last time is was .5 (negative).  The range for all of these labs was <6 was considered "normal", Between 6 and 8 was like a mild positive and >8 was positive.  So if your lab was the same your result would have been a clear positive for that test.  Just so you know, my son had that test positive with others negative and we just had a negative biopsy.  He also came back negative for the same test (while consuming gluten).  We are being told that it could have been some kind of infection causing the positive, and now that it is negative we are being told not to worry but to trust the results we are getting now (including the biopsy).  Just thought I would share.

Thanks for sharing your son's experience.  Talk about a roller coaster ride! It really is frustrating not being able to pin things down, even more so for you when it's your son you're worrying about.  Thanks again, I'll keep this information in mind.

heliosue Apprentice

Yes.  Lab normal ranges can vary quite a bit.  I've seen from 0-4 up to 0-20.  My lab range was the 0-20, and everything above a 20 was considered high.  If you have 19.8, you are not a celiac but 20.2 probably is.   :rolleyes:   My result was stated at greater than 200 so I have no idea what it actually was - could have been 201 or 1000.   ;)

 

The normal range usually starts at 0 though.  If your 10 was high, your upper normal limit was probably 4, 5, or 6.  Perhaps you can request a copy of the lab report and then you'll know for sure.

 

If you want to stay gluten-free yet want to verify your diagnosis, try retesting after 6 months.  If your result has come down, it probably was celiac disease.... A positive test result means it is probably celiac disease anyways.  Those tests are pretty specific to celiac disease. This report shows that the specificity of a positive for celiac disease for the tTG IgG (SP) is about 95%. Open Original Shared Link

 

Best wishes.

Thanks. I just read the page you linked to and copied it into my Celiac file.  My doctor (internist) doesn't seem to think that it's important that I know one way or the other, but I do think that I should let nieces and brother know if it is Celiac.  He said that  a 10 on the TTG, IgG was borderline, but he couldn't tell me what the benchmarks were in upper range.  Also, I had to remind him that my blood labs a year ago showed that I was low in iron, B-12, and folic acid and he had me taking supplments for each. Six months ago, my dentist asked what I was doing that caused me to be losing enamel on my teeth. I had no idea. So many of the possible symptoms can be symptoms for myriad other illnesses. Thanks for mentioning taking the Celiac panel again in 6 months. It hadn't occurred to me that if the antibody count decreased that that would be a good indication of celiac disease.  From my perspective that is so much more preferable to eating gluten again for any length of time.  Thanks again for your help.  It really does ease my mind to know that there are folks like those in this forum who can relate and answer questions for me.

nvsmom Community Regular

I think most people around here can relate to your struggle.  Those who had a stomach ache for a month, were diagnosed with clear results, and trained on the gluten-free diet, aren't the ones who come here... Sadly, we are the majority of celiacs.  ;)

Brit1612 Apprentice

Thanks for sharing your son's experience.  Talk about a roller coaster ride! It really is frustrating not being able to pin things down, even more so for you when it's your son you're worrying about.  Thanks again, I'll keep this information in mind.

You're right it is really frustrating when it is happening to your child, especially a child that can't even talk.  I can't ask him how are you feeling, or explain to him the things he's been having to go through.  But I am still grateful for his health; I know there are parents out there dealing with life threatening illness in their children, so I try to keep it in perspective.  Hope you get answers quicker and easier than we have!


Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):



Celiac.com Sponsor (A8-M):



Archived

This topic is now archived and is closed to further replies.

  • Get Celiac.com Updates:
    Support Celiac.com:
    Join eNewsletter
    Donate

  • Celiac.com Sponsor (A17):
    Celiac.com Sponsor (A17):





    Celiac.com Sponsors (A17-M):




  • Recent Activity

    1. - knitty kitty replied to Trish G's topic in Gluten-Free Foods, Products, Shopping & Medications
      7

      Fiber Supplement

    2. - knitty kitty replied to kpf's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
      14

      ttg iga high (646 mg/dl) other results are normal

    3. - Trish G replied to Trish G's topic in Gluten-Free Foods, Products, Shopping & Medications
      7

      Fiber Supplement

    4. - Wheatwacked replied to Larzipan's topic in Related Issues & Disorders
      36

      Has anyone had terrible TMJ/ Jaw Pain from undiagnosed Celiac?

    5. - Wheatwacked replied to Larzipan's topic in Related Issues & Disorders
      36

      Has anyone had terrible TMJ/ Jaw Pain from undiagnosed Celiac?


  • Celiac.com Sponsor (A19):



  • Member Statistics

    • Total Members
      132,344
    • Most Online (within 30 mins)
      7,748

    GFBB95
    Newest Member
    GFBB95
    Joined

  • Celiac.com Sponsor (A20):


  • Forum Statistics

    • Total Topics
      121.5k
    • Total Posts
      1m

  • Celiac.com Sponsor (A22):





  • Celiac.com Sponsor (A21):



  • Upcoming Events

  • Posts

    • Hmart
      Hello again. Thank you for the responses to date. I have had several follow-ups and wanted to share what I’ve learned. About a month after my initial blood test and going gluten free, my TtG went from 8.1 to 1.8. I have learned that my copper is low and my B6 is high. My other vitamins and nutrients are more or less in range. After I glutened myself on 10/24, I have been strict about being gluten free - so about a month. I have been eating dairy free and low FODMAP as well because it’s what my stomach allows. Baked fish, potatoes, rice, etc. Whole foods and limited Whole foods. I have continued to lose weight but it has slowed down, but a total of about 15 pounds since I went gluten free. Along with stomach pain, my symptoms included nausea, body and joint pain, a burning sensation throughout my body and heart rate spikes. I still have them but I have them less now. These are the symptoms that led to my doctor appointments and subsequent diagnosis. I also did the DNA screening and was positive. So, at this point, the answer is yes, I have celiac. I have two questions for this group. Any ideas on why my enteropathy was so severe (marsh 3B) and my TtG was so minimal? Is that common? Or are there other things to consider with that combo? And this recovery, still having pain and other symptoms a month later (7 weeks gluten free and 4 weeks after the glutening) normal? I’m going to continue down this path of bland foods and trying to heal but would love to understand the reasons for the long journey. I read so much about people who stop eating gluten and feel amazing. I wish that was my experience but it certainly hasn’t been. Thank you again!
    • knitty kitty
      @Trish G,  I like dates, they have lots if fiber as well.  But what I found helped most was taking Thiamine (in the form Benfotiamine which helps promote intestinal healing), Pyridoxine B 6, Riboflavin B 2, and magnesium, and Omega Three fats. The absorption of nutrients is affected by Celiac disease which damages the intestinal lining of the small intestines where our nutrients are absorbed.  If you have constipation, where your body is rather pushing your food away and not interacting with it, the nutrients in the food are not being released and absorbed.  You can develop deficiencies in all the vitamins and minerals necessary for the body to function properly.   The B vitamins cannot be stored for long, so they must be replenished daily.  Thiamine B 1 stores can run out in as little as three days.  Constipation (or diarrhea or alternating) is one of the first symptoms of thiamine deficiency.  Thiamine needs magnesium, Pyridoxine B 6, and Riboflavin B 2 to make the intestinal tract function.  Thiamine and Niacin make digestive enzymes.  Thiamine provides the energy for nerve impulses to carry messages to the brain and back about digestion.  Thiamine provides the energy for the muscle contractions which move your food through the digestive tract. High calorie meals containing lots of starches and sugars can deplete thiamine stores quickly because more thiamine is required to turn them into energy.   Are you taking any vitamin and mineral supplements?  Correction of malnutrition is very important in Celiac disease.  Thiamine, the other B vitamins and magnesium will help with constipation better than adding more fiber.  What did your nutritionist recommend you take, besides just the fiber? The association between dietary vitamin B1 intake and constipation: a population-based study https://pmc.ncbi.nlm.nih.gov/articles/PMC11100033/ Thiamine, gastrointestinal beriberi and acetylcholine signaling https://pmc.ncbi.nlm.nih.gov/articles/PMC12014454/ Association between dietary vitamin B6 intake and constipation: a population-based study https://pmc.ncbi.nlm.nih.gov/articles/PMC11584952/
    • knitty kitty
      @kpf, Were you eating ten grams or more of gluten daily in the month preceding your antibody blood tests? TTg IgA antibodies are made in the intestines.  Ten grams of gluten per day for several weeks before testing is required to provoke sufficient antibody production for the antibodies to leave the intestines and enter the blood stream and be measured in blood tests. If you had already gone gluten free or if you had lowered your consumption of gluten before testing, your results will be inaccurate and inconclusive.   See link below on gluten challenge guidelines. Have you had any genetic testing done to see if you carry genes for Celiac disease?  If you don't have genes for Celiac, look elsewhere for a diagnosis.  But if you have Celiac genes, you cannot rule out Celiac disease. You mentioned in another post that you are vegetarian.  Have you been checked for nutritional deficiencies?  The best sources of the eight essential B vitamins are found in meats.  Do you supplement any of the B vitamins as a vegetarian? Deficiency in Thiamine Vitamin B 1 is strongly associated with anemia which can cause false negatives on antibody tests.  Fatigue, numbness or tingling in extremities, difficulty with coordination, headaches and anemia are strongly associated with thiamine deficiency.  Other B vitamins that contribute to those symptoms are Riboflavin B 2, Pyridoxine B 6, Folate B 9 and B12 Cobalamine.  The eight B vitamins all work together with minerals like magnesium and iron.  So your symptoms are indicative of B vitamin deficiencies.  You can develop vitamin and mineral deficiencies just being a vegetarian and not eating good sources of B vitamins like meat.  B vitamin deficiencies are found in Celiac due to the malabsorption of nutrients because the lining of the intestines gets damaged by the antibodies produced in response to gluten.    
    • Trish G
      Thanks, I'm not a big fan of prunes but did add them back after stopping the Benefiber. Hoping for the best while I wait to hear back from Nutritionist for a different fiber supplement.  Thanks again
    • Wheatwacked
      If you were wondering why milk protein bothers you with Celiac Disease.  Commercial dairies supplement the cow feed with wheat, which becomes incorporated in the milk protein. Milk omega 6 to omega 3 ratio: Commercial Dairies: 5:1 Organic Milk: 3:1 Grass fed milk: 1:1
×
×
  • Create New...

Important Information

NOTICE: This site places This site places cookies on your device (Cookie settings). on your device. Continued use is acceptance of our Terms of Use, and Privacy Policy.