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News: Celiac.com: Celiac Disease and Nonceliac Gluten Sensitivity


Scott Adams

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Scott Adams Grand Master

This review discusses the the role of a gluten-free diet in the clinical management of celiac disease and nonceliac gluten sensitivity and highlights the ...

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    • trents
      Welcome to the forum, @gemknorodo! In your post you actually mention two antibody tests that are commonly run when checking for celiac disease. The first is the TG-IgA. You do not give a score for that one. The second one is the Immunoglobulin A for which you scored 3.06. This is above the normal range. This test is also commonly known as "total IGA". What you need to know is that it is not a test that detects celiac disease per se. It is used to determine if the person being tested is IGA deficient. IGA deficiency results in inaccurate scores for the IGA tests that are used to detect celiac disease such as the TG IgA. IGA deficiency depresses the other IGA scores and so, it can cause false negatives. In your case, you are not IGA deficient so that is not an issue for you. In case you are wondering, I do not know that there is any particular significance or health risks associated with higher than normal total IGA. But that is something you can ask your physician. Here is an article that outlines the various tests that can be run when checking for celiac disease: There are other IGA tests that can be run when checking for celiac disease and there are also IGG tests that can be run to check for celiac disease. You might talk to your physician about having a more complete "celiac panel" run. Your physician might also want to refer you to a gastroenterologist who might do more extensive antibody panel or even an endoscopy with a biopsy to check for the damage to the small bowel lining caused by celiac disease. May we ask what symptoms you are experiencing? What has led up to you being tested for celiac disease?
    • DebJ14
      If your son does go completely gluten free, then he will find that occasional consumption of gluten will result in a stronger reaction.  The longer you are off of it, the worse the reaction.  When I was first diagnosed I would break out in a rash or get a headache if I consumed gluten.  As time went on I would get diarrhea and vomit profusely.  The time between accidental gluten consumption and the ss** show starting gets smaller and smaller.  I always know where the bathroom is wherever I am because even when they claim the food is gluten free, it may not be and so many people think a little can't hurt you. I have a 20 year old grandson and an 18 year  old, both celiacs, and both athletes.  The trick to always having gluten free food is to prepare ahead of time and they always bring something gluten-free with them. My family  has adopted the motto, "When in doubt, do without."  Otherwise the consequences can be dire. We have 5 Celiacs in the family and 2 with NSGS.  Those with NSGS also have strong reactions the longer they are off of gluten.
    • gemknorodo
      Hello I have recently had several blood tests and one of them was for celiac, I have had the following result TG IgA level Immunoglobulin A Level 3.06 g/L (range 0.8 - 2.8) Is this in indicator of celiac? My GP has marked it as borderline and said I need to make an appt to discuss it.      
    • trents
      Pua, do you understand that genetic testing cannot be used as proof of having celiac disease as it only establishes the potential to develop active celiac disease? About 40% of the population has the genetic potential to develop active celiac disease but only about 1% actually develop it. However, it can be used as a rule out measure.
    • Pua
      Mahalo for all of the answers this has been super helpful. He is doing so much better on a gluten free diet. I may consider genetic testing as I never thought of that as an option and I definitely don’t want to go the usual route and have to give him gluten again for the test. It’s nice to have an “official diagnosis” but as long as he’s healthy I don’t care.  mahalo again!
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