Jump to content
  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.


  • Celiac.com Sponsor (A1):
    Celiac.com Sponsor (A1-M):
  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

News: Celiac.com: PvP Biologics Creates First Therapeutic Enzyme for Celiac Disease


Scott Adams

Recommended Posts

Scott Adams Grand Master

Around 1 percent of the American population is affected by celiac disease. For the ... Most are slow or don't target all of the gluten molecules. ... “The obvious [benefit is that] you don't have to worry about following a gluten-free diet.

Open Original Shared Link


Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):



Celiac.com Sponsor (A8-M):



Ennis-TX Grand Master

Good in theory but I have a feeling they will flop like all of the other enzyme therapies.....like trying to prevent the sticky floor and mess of pouring a glass of juice on the floor by putting down a pile of paper towels...you going to get most of it but some is going to get through some is going to splatter and cause collateral issues......you can not just intercept and try to prevent a reaction to a bloody molecule smaller then a germ, a dang protein, buy trying to eliminate it after it has entered the body......like drinking bleach/antifreeze and trying to puke it all back up....it is in your body your going to get some ill effect maybe not as bad or quick.  

Key is eliminating the gluten before it enters the body, or turning off the bodies response to the protein. THOSE would be what we need, I see more potential in a kind of "gluten vaccine" that might turn off our immune response to gluten. Even is just a temporary measure like say a crispr RNA treatment or a targeted immune suppressant.

I think these doctors might have to experience how even the tiniest CC effects many of us and how before they try coming up with a half baked treatment of dealing with it in the body.

Archived

This topic is now archived and is closed to further replies.

  • Get Celiac.com Updates:
    Support Celiac.com:
    Join eNewsletter
    Donate

  • Celiac.com Sponsor (A17):
    Celiac.com Sponsor (A17):





    Celiac.com Sponsors (A17-M):




  • Recent Activity

    1. - Wheatwacked replied to Jmartes71's topic in Coping with Celiac Disease
      14

      Related issues

    2. - sc'Que? commented on Celiac.com Sponsor: Review's article in Product Reviews
      2

      Bold Taste, No Alcohol & Crafted to Remove Gluten: Daura Non-Alc Beer Takes Alcohol-Free Beer to the Next Level

    3. - Theresa2407 replied to Aya77's topic in Gluten-Free Foods, Products, Shopping & Medications
      9

      Books about celiac

    4. - Known1 replied to Aya77's topic in Gluten-Free Foods, Products, Shopping & Medications
      9

      Books about celiac

    5. - knitty kitty replied to Colleen H's topic in Coping with Celiac Disease
      3

      Barilla gluten free pasta

  • Celiac.com Sponsor (A19):
  • Member Statistics

    • Total Members
      133,473
    • Most Online (within 30 mins)
      7,748

    Eddie Graham
    Newest Member
    Eddie Graham
    Joined
  • Celiac.com Sponsor (A20):
  • Celiac.com Sponsor (A22):
  • Forum Statistics

    • Total Topics
      121.6k
    • Total Posts
      1m
  • Celiac.com Sponsor (A21):
  • Who's Online (See full list)

  • Upcoming Events

  • Posts

    • Wheatwacked
      Did they ever tell you specifically which vitamins would interfere with which tests? Fermented pickles source of thiamine  and other B-vitamins, The fermentation process with lactic acid bacteria increases the nutrient value.   Colonies of beneficial bacteria can help crowd out the the bad SIBO. Have you had the rash biopsied for Dermatitus Herpetiformus?  Atopic Dermatitis and dermatitis herpetiformis share symtoms and atopic dermatitis patients have higher risk of dermatitis herpetiformis.  dermatitis herpetiformis is a symptom of Celiac diagnosis. When I had the carotid artery stent, the hospital put down "wheat allergy" for the food service.  I guess allergy puts the fear of god in them more than the misunderstood Celiac Disease.  Whatever keeps me alive in this world.   
    • Theresa2407
      You are correct.  Same place.  I have used their site for so long and have it bookmarked.  Still living in past.  Our support group was affiliated with them.
    • Known1
      Hmm, I think you mean the Gluten Intolerance Group®?  Their website is not gig.net.  Maybe it was at one point?  I am new to all of this, but did find their website here:  https://gluten.org/ Kind Regards, Known1
    • knitty kitty
      @Scott Adams, You're right about corn and wheat not sharing similarities in the 33-mer peptide segment of gluten.  Corn has a completely different peptide that causes an autoimmune reaction because it attaches to HLA-DQ8.  Casein in dairy shares with wheat similarities in the33-mer peptide chain. Sorry about the oversimplification.  Maize Prolamins Could Induce a Gluten-Like Cellular Immune Response in Some Celiac Disease Patients https://pmc.ncbi.nlm.nih.gov/articles/PMC3820067/
    • Scott Adams
      I just want to mention that corn and wheat do both contain storage proteins (corn has zein, wheat has gliadin and other gluten proteins), and there are some small similarities in certain amino acid sequences. However, those similarities are not considered medically equivalent, and corn proteins do not trigger the autoimmune response of celiac disease in the vast majority of people with celiac. Celiac disease specifically involves an immune reaction to gluten peptides found in wheat, barley, and rye. Corn is classified as gluten-free because its proteins do not activate that same immune pathway in most individuals. Although corn intolerance is very real, the explanation about the proteins being the same is oversimplified to the point where it's not accurate.
×
×
  • Create New...

Important Information

NOTICE: This site places This site places cookies on your device (Cookie settings). on your device. Continued use is acceptance of our Terms of Use, and Privacy Policy.