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News: Celiac.com: PvP Biologics Creates First Therapeutic Enzyme for Celiac Disease


Scott Adams

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Scott Adams Grand Master

Around 1 percent of the American population is affected by celiac disease. For the ... Most are slow or don't target all of the gluten molecules. ... “The obvious [benefit is that] you don't have to worry about following a gluten-free diet.

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Ennis-TX Grand Master

Good in theory but I have a feeling they will flop like all of the other enzyme therapies.....like trying to prevent the sticky floor and mess of pouring a glass of juice on the floor by putting down a pile of paper towels...you going to get most of it but some is going to get through some is going to splatter and cause collateral issues......you can not just intercept and try to prevent a reaction to a bloody molecule smaller then a germ, a dang protein, buy trying to eliminate it after it has entered the body......like drinking bleach/antifreeze and trying to puke it all back up....it is in your body your going to get some ill effect maybe not as bad or quick.  

Key is eliminating the gluten before it enters the body, or turning off the bodies response to the protein. THOSE would be what we need, I see more potential in a kind of "gluten vaccine" that might turn off our immune response to gluten. Even is just a temporary measure like say a crispr RNA treatment or a targeted immune suppressant.

I think these doctors might have to experience how even the tiniest CC effects many of us and how before they try coming up with a half baked treatment of dealing with it in the body.

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    • Midwesteaglesfan
      Back home after the scope.  Dr said as soon as he got in there it was clear signs of celiacs.  Must be a decent amount of damage.  I don’t remember the post procedure conversation as the anesthesia was still wearing off but that’s what my wife says anyway.  Still the biopsy results to come back but pretty definitive and now I get to learn to live gluten free
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      Welcome to the forum! Do you mean this article, and if so, I don't think these are available yet.  
    • Scott Adams
      First of all, I want to wish you the very best of luck with your procedure today. It's completely understandable to feel a mix of apprehension and hope. Your proactiveness in researching and advocating for that endoscopy was incredibly smart; securing that formal diagnosis is crucial for both insurance and long-term health management. While it's natural to worry that those five gluten-free days could affect the results, your logic is spot-on—it's highly unlikely your intestines healed completely in that short time, and the fact that your joint pain and stomach issues have flared back up aggressively after reintroducing gluten is a very strong, and unfortunate, sign that the inflammation is indeed present and active. It's also very common for people to look back and connect dots, like your lifelong migraines, once a potential celiac diagnosis is on the table, as it's a systemic condition with many non-gastrointestinal symptoms. I truly hope this scope provides the clear answers you need to finally start on the right path to managing your health and finding lasting relief from the fatigue and pain. Safe travels for your drive, and here's hoping for a definitive answer and a brighter, healthier chapter ahead.
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      This article might be helpful:  
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