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Confused about actual diagnosis/if more diagnostics are indicated

queenofcups

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queenofcups Newbie
queenofcups
Posted

Hi, 

Do these lab values warrant more diagnostics like a small bowel biopsy? I am currently symptomatic. I apologize as I find this confusing (brain fog isn't exactly helping.) 

Summer 2016:

EliA Celikey IgA (Tissue Transglutaminase Ab IgA) 1.1 U/mL <7.0 U/mL
This test is analyzed using the Phadia 250 method specificreagent kit, the 
recommended reference intervals using thisplatform are:<7 Negatiive7-10 
Equivocal>10 Positive
Gliadin DP IgA Ab 5.9 U/mL <7.0 U/mL
This test is analyzed using the Phadia 250 method specificreagent kit, the 
recommended reference intervals using thisplatform are:<7 Negatiive7-10 
Equivocal>10 Positive
Gliadin DP IgG Ab 3.1 U/mL <7.0 U/mL
This test is analyzed using the Phadia 250 method specificreagent kit, the 
recommended reference intervals using thisplatform are:<7 Negatiive7-10 
Equivocal>10 Positive
Reticulin Ab IgA Negative   Negative
Additional Testing not indicated.    

Fall 2017: (was gluten free for 8 months and started reintroducing it but then the joint pain, flushing, brain fog, dizziness, rashes/poor skin healing, and frequent colds/URIs commenced)

 

Component Your Value Standard Range
Deamidated Gliadin Ab, IgA 13 units 0 - 19 units

Negative 0 - 19
Weak Positive 20 - 30
Moderate to Strong Positive >30

The result says negative but my doctor insists I go gluten free again. Would someone shed any light? 

Thank you.

 

 

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queenofcups Newbie
queenofcups
Posted
  • Author

I'm sorry as this was posted in the wrong forum. 

kareng Grand Master
kareng
Posted
19 minutes ago, queenofcups said:

I'm sorry as this was posted in the wrong forum. 

I fixed it  :D

 

cyclinglady Grand Master
cyclinglady
Posted

Looks like you tested negative on the celiac blood tests.  Who ordered the tests?  Reticulin has not been used for more than a decade.   This makes me think that your doctor may not be so celiac-savvy.  Why does that matter?  Some 10% of celiacs are seronegative.  If celiac disease is strongly suspected, a  GI might want to confirm with an endoscopy.   Also, you did not say how long your gluten challenge was before that last blood test.  A challenge requires a person to be on a gluten diet for 8 to 12 weeks:

Open Original Shared Link

Do you have any risk factors, like family history, another autoimmune disorder, IBS?  

Open Original Shared Link

It seems like the Gluten Free diet is helping your current symptoms of joint pain and rashes.  So, then you would be considered Non-Celiac Gluten Sensitive/Intolerant.  That diagnosis is done when celiac disease has been ruled out.  I can see why he recommended the gluten free diet.  You felt better!  

You are going to have to decide if pursuing a celiac disease diagnosis is necessary for you.  I wish you well.  

 

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