Jump to content
This site uses cookies. Continued use is acceptance of our Terms of Use and Privacy Policy. More Info... ×
  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.




  • Celiac.com Sponsor (A1):



    Celiac.com Sponsor (A1-M):


  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Wheat allergy ( skin test)


lilo

Recommended Posts

lilo Enthusiast

 Did anyone here got a diagnosis for wheat allergy through skin test ? How did you do it ? 


Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):



Celiac.com Sponsor (A8-M):



trents Grand Master

Before I say anything else I just want to make sure you realize that Celiac Disease is not an allergy. Neither is gluten intolerance and allergy. I could not be sure from your question whether or not you understood this.

Celiac Disease is an autoimmune disorder. People who have it get an autoimmune reaction that does damage to the lining of the small bowel when they consume wheat, barley or rye. Autoimmune disorders are where the body attacks its own tissues and is different than an allergy. With allergies the body reacts to a foreign substance as an invader and begins to attack the foreign substance but not the body's own tissues. In the case of allergies this attack of the invader may cause inflammation such as nasal discharge and congestion and swelling of the tissues that lining of the airway (which can be life-threatening) but it is a byproduct of the effort to rid the body of the invader or neutralize it. The autoimmune reaction of Celiac disease is a very different immune system process than is an allergic reaction.

Gluten intolerance is neither an allergy or an autoimmune response. It is very similar to lactose intolerance in that both are caused by the lack of specific enzymes in the digestive track needed to break down substances in food. These undigested substances upset the microbiology of the bowel causing gas and diarrhea but do not attack the tissues of the intestines themselves.

As I recall, my skin prick allergy testing and my blood analysis allergy testing (or one of them at least) showed I had a mild allergy to wheat but none to gluten per se. Yet, by way of intestinal biopsy I am a confirmed Celiac. Since gluten is found in wheat that really shed light for me on the fact that Celicac disease is something different than an allergy to wheat. My whole point is that skin prick testing is useless for diagnosing Celiac disease or gluten intolerance. So testing positive for allergies to wheat or even gluten says nothing about whether or not you have Celiac Disease or gluten intolerance. 

And in fact, there is great deal of skepticism in the medical community as to whether allergy testing of any kind (as it is presently practiced) has much value. The correlation between tests results and real symptoms experienced by exposure to the substances you test positive for is often very poor. And this is confirmed in my own personal experience.

lilo Enthusiast
2 hours ago, trents said:

Before I say anything else I just want to make sure you realize that Celiac Disease is not an allergy. Neither is gluten intolerance and allergy. I could not be sure from your question whether or not you understood this.

Celiac Disease is an autoimmune disorder. People who have it get an autoimmune reaction that does damage to the lining of the small bowel when they consume wheat, barley or rye. Autoimmune disorders are where the body attacks its own tissues and is different than an allergy. With allergies the body reacts to a foreign substance as an invader and begins to attack the foreign substance but not the body's own tissues. In the case of allergies this attack of the invader may cause inflammation such as nasal discharge and congestion and swelling of the tissues that lining of the airway (which can be life-threatening) but it is a byproduct of the effort to rid the body of the invader or neutralize it. The autoimmune reaction of Celiac disease is a very different immune system process than is an allergic reaction.

Gluten intolerance is neither an allergy or an autoimmune response. It is very similar to lactose intolerance in that both are caused by the lack of specific enzymes in the digestive track needed to break down substances in food. These undigested substances upset the microbiology of the bowel causing gas and diarrhea but do not attack the tissues of the intestines themselves.

As I recall, my skin prick allergy testing and my blood analysis allergy testing (or one of them at least) showed I had a mild allergy to wheat but none to gluten per se. Yet, by way of intestinal biopsy I am a confirmed Celiac. Since gluten is found in wheat that really shed light for me on the fact that Celicac disease is something different than an allergy to wheat. My whole point is that skin prick testing is useless for diagnosing Celiac disease or gluten intolerance. So testing positive for allergies to wheat or even gluten says nothing about whether or not you have Celiac Disease or gluten intolerance. 

And in fact, there is great deal of skepticism in the medical community as to whether allergy testing of any kind (as it is presently practiced) has much value. The correlation between tests results and real symptoms experienced by exposure to the substances you test positive for is often very poor. And this is confirmed in my own personal experience.

 I know that celiac disease is not an allergy. I just wanted to test if i also have wheat allergy too.Thank you for your reply.

tessa25 Rising Star

To test for an allergy you go to the allergist, and they prick the skin with allergens you select to be tested from the list. They write numbers on your arms or back then prick you with each allergen. They also prick you with histamine and a control. A raised bump after 10 or 15 minutes signifies an allergic reaction. The histamine getting a bump and the control not getting a bump validates the test.

 

cyclinglady Grand Master

Just for educational purposes, celiac disease and allergies fall under the umbrella of hypersensitivity.  Wikipedia explains it well for this application.

Open Original Shared Link

You can have several types of hypersensitivities concurrently.   You can get tested for IgE allergies, but it is not always accurate.  What make you think you have a wheat allergy in addition to celiac disease?  Hives, swelling, blood pressure drops, breathing difficulties, itchiness, vomiting, abdominal pain, losing consciousness?  

If you do get tested, please share!  I find this fascinating!  

Archived

This topic is now archived and is closed to further replies.


  • Celiac.com Sponsor (A19):



  • Member Statistics

    • Total Members
      127,936
    • Most Online (within 30 mins)
      7,748

    Sary Diab
    Newest Member
    Sary Diab
    Joined

  • Celiac.com Sponsor (A20):


  • Forum Statistics

    • Total Topics
      121k
    • Total Posts
      70.5k

  • Celiac.com Sponsor (A22):





  • Celiac.com Sponsor (A21):



  • Upcoming Events

  • Posts

    • Nicbent35
      Well I had a moment yesterday morning where I accidentally gave her gluten. She wanted what I was eating and I forgot and let her have a few bites of toast. It was a really bad night last night with her behavior. Will a few bites of bread influence their behavior that much or could it just be a coincidence?
    • Scott Adams
      The first set of results show two positive results for celiac disease, so at the very least it looks like you could have it, or at the least NCGS.   Approximately 10x more people have non-celiac gluten sensitivity than have celiac disease, but there isn’t yet a test for NCGS. If your symptoms go away on a gluten-free diet it would likely signal NCGS.      
    • Scott Adams
      Elevated tissue transglutaminase IgA (tTG-IgA) levels are highly specific for celiac disease, and they are a key biomarker used in its diagnosis. However, there are some rare instances where elevated tTG-IgA levels have been reported in conditions other than celiac disease. While these cases are not common, they have been documented in the literature. Below are some examples and references to studies or reviews that discuss these scenarios:  1. Non-Celiac Gluten Sensitivity (NCGS)    - NCGS typically does not cause elevated tTG-IgA levels, as it is not an autoimmune condition. However, some individuals with NCGS may have mild elevations in tTG-IgA due to intestinal inflammation or other factors, though this is not well-documented in large studies.    - Reference: Catassi, C., et al. (2013). *Non-Celiac Gluten Sensitivity: The New Frontier of Gluten-Related Disorders*. Nutrients, 5(10), 3839–3853. [DOI:10.3390/nu5103839](https://doi.org/10.3390/nu5103839)  2. Autoimmune Diseases    - Elevated tTG-IgA levels have been reported in other autoimmune conditions, such as type 1 diabetes, autoimmune hepatitis, and systemic lupus erythematosus (SLE). This is thought to be due to cross-reactivity or polyautoimmunity.    - Reference: Sblattero, D., et al. (2000). *The Role of Anti-Tissue Transglutaminase in the Diagnosis and Management of Celiac Disease*. Autoimmunity Reviews, 1(3), 129–135. [DOI:10.1016/S1568-9972(01)00022-3](https://doi.org/10.1016/S1568-9972(01)00022-3)  3. Chronic Liver Disease    - Conditions like chronic hepatitis or cirrhosis can sometimes lead to elevated tTG-IgA levels, possibly due to increased intestinal permeability or immune dysregulation.    - Reference: Vecchi, M., et al. (2003). *High Prevalence of Celiac Disease in Patients with Chronic Liver Disease: A Role for Gluten-Free Diet?* Gastroenterology, 125(5), 1522–1523. [DOI:10.1016/j.gastro.2003.08.031](https://doi.org/10.1016/j.gastro.2003.08.031)  4. Inflammatory Bowel Disease (IBD)    - Some patients with Crohn’s disease or ulcerative colitis may have elevated tTG-IgA levels due to intestinal inflammation and damage, though this is not common.    - Reference: Walker-Smith, J. A., et al. (1990). *Celiac Disease and Inflammatory Bowel Disease*. Journal of Pediatric Gastroenterology and Nutrition, 10(3), 389–391. [DOI:10.1097/00005176-199004000-00020](https://doi.org/10.1097/00005176-199004000-00020)  5. Infections and Parasites    - While infections (e.g., giardiasis) are more commonly associated with false-positive tTG-IgA results, chronic infections or parasitic infestations can sometimes lead to elevated levels due to mucosal damage.    - Reference: Rostami, K., et al. (1999). *The Role of Infections in Celiac Disease*. European Journal of Gastroenterology & Hepatology, 11(11), 1255–1258. [DOI:10.1097/00042737-199911000-00010](https://doi.org/10.1097/00042737-199911000-00010)  6. Cardiac Conditions    - Rarely, heart failure or severe cardiovascular disease has been associated with elevated tTG-IgA levels, possibly due to gut ischemia and increased intestinal permeability.    - Reference: Ludvigsson, J. F., et al. (2007). *Celiac Disease and Risk of Cardiovascular Disease: A Population-Based Cohort Study*. American Heart Journal, 153(6), 972–976. [DOI:10.1016/j.ahj.2007.03.019](https://doi.org/10.1016/j.ahj.2007.03.019)  Key Points: - Elevated tTG-IgA levels are highly specific for celiac disease, and in most cases, a positive result strongly suggests celiac disease. - Other conditions causing elevated tTG-IgA are rare and often accompanied by additional clinical findings. - If celiac disease is suspected, further testing (e.g., endoscopy with biopsy) is typically required for confirmation. If you’re looking for more specific studies, I recommend searching PubMed or other medical databases using terms like "elevated tTG-IgA non-celiac" or "tTG-IgA in non-celiac conditions." Let me know if you’d like help with that!
    • MaryMJ
      I called zero water and they state their filters do not contain gluten or gluten containing ingredients. 
    • trents
      I agree. Doesn't look like you have celiac disease. Your elevated DGP-IGG must be due to something else. And it was within normal at that after your gluten challenge so it is erratic and doesn't seem to be tied to gluten consumption.
×
×
  • Create New...