Jump to content
This site uses cookies. Continued use is acceptance of our Terms of Use and Privacy Policy. More Info... ×

  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.



  • Celiac.com Sponsor (A1):

    Celiac.com Sponsor (A1-M):

  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

transglutaminase Igg results

Jplexman

Recommended Posts

Jplexman Newbie
Jplexman
Posted

Hi, I’m new here. I’m waiting for a endoscope and colonoscopy in 10 days. I have iron defiency anemia and receive iron infusions. 

I had the celiac panel done and most of it shoed negative accept igg was marked high at 20 or 21.

so now I’m confused. Should I still have the biopsy or is it unnecessary ? 

 

 

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


ravenwoodglass Mentor
ravenwoodglass
Posted

Yes get the endo done. Make sure you keep eating gluten until after the scope is done.  What tests did they do of the celiac panel?  Some doctors don't run a full panel and in addition you don't need to be positive on all the tests to be celiac. There are folks that are false negative on the blood tests and still have lots of damage on the biopsies. Make sure your doctor takes at least 6 different biopsies from different areas. even then damage can be patchy and be missed so do give the diet a good strict go no matter what the test results. Do read the 'Newbie 101' at the top of the Coping section and ask any questions you need.

Jplexman Newbie
Jplexman
Posted
  • Author

Thanks I appreciate it. The numbers seem to all be different on the internet for threshold. Do you know what range is normal or positive for igg antibodies ? 

squirmingitch Veteran
squirmingitch
Posted

Each lab has it's own values. There is no across the board standard. The lab report should have the range #'s.

Archived

This topic is now archived and is closed to further replies.

Go to topic listing
  • Celiac.com Sponsor (A19):


  • Member Statistics

    • Total Members
      125,877
    • Most Online (within 30 mins)
      7,748
    hannahc
    Newest Member
    hannahc
    Joined
  • Celiac.com Sponsor (A20):

  • Forum Statistics

    • Total Topics
      120.9k
    • Total Posts
      69k
  • Celiac.com Sponsor (A22):



  • Celiac.com Sponsor (A21):


  • Upcoming Events

  • Posts

    • trents
      9 year old- questionable results

      By trents · Posted

      Welcome to the forum, @ABP! We can't comment on the test numbers you give as you didn't include the range for negative. Different labs use different units and different ranges. There are no industry standards for this so we need more information. If your daughter doesn't have celiac disease she still could have NCGS (Non Celiac Gluten Sensitivity) which some experts believe can be a precursor to celiac disease and is 10x more common than celiac disease. However, there is no test for it yet but it does share many of the same symptoms with celiac disease. Both require complete abstinence from gluten.  It is seldom the case during testing where all tests are positive, even for those who do have celiac disease. This is no different than when diagnosing other medical conditions and that is why it is typical to run numbers of tests that come at things from different angles when seeking to arrive at a diagnosis. It seems like you are at the point, since you have had both blood antibody testing and endoscopy/biopsy done, that you need to trial the gluten free diet. If her symptoms improve then you know all you need to know, whatever you label you want to give it. But given that apparently at least one celiac antibody blood test is positive and she has classic celiac symptoms such as slow growth, constipation and bloating, my money would be on celiac disease as opposed to NCGS.
    • ABP
      9 year old- questionable results

      By ABP · Posted

      My nine-year-old daughter has suffered with severe constipation and bloating for years as well as frequent mouth sores, and keratosis Polaris on her arms. She also has recently decreased on her growth curve her % going down gradually.  After seeing a gastroenterologist, her IgG GLIADIN (DEAMIDATED) AB (IGG) was 22.4 while her IGA was normal. Her TISSUE TRANSGLUTAMINASE AB, IGA was 11.9.  Most recently her genetic test for celiac was positive.  After an endoscopy her tissue showed inflammation of the tissue as well as , increased intraepithelial lymphocytes (IELs) but there was no blunting of the change in the villi.    It seems that every result that we get one out of two things positive rather than all leading to an inconclusive diagnosis. While we do have another appointment with the doctor to go over the results. I'm curious based on this information what others think.    I would hate to have her eliminate gluten if not necessary- but also don't want to not remove if it is necessary.    Signed Confused and Concerned Mama
    • Scott Adams
      Gluten Free ADHD medications

      By Scott Adams · Posted

      I guess using "GF" instead of "PL" would have been too easy! 😉
    • trents
      Help with blood test result

      By trents · Posted

      I was wrong, however, about there being no particular health concerns associated with high total IGA: https://www.inspire.com/resources/chronic-disease/understanding-high-iga-levels-causes-impacts/ So maybe the physician's "borderline" remark is relevant to that.
    • trents
      Help with blood test result

      By trents · Posted

      Sometimes that is the case but what is curious to me is the remark by your physician about being "borderline". I assume he was referring to the total IGA score but it just seems like an irrelevant remark when it is on the high side rather than being deficient.
×
×
  • Create New...