Study to Evaluate the Efficacy and Safety of Larazotide Acetate for the Treatment of Celiac Disease

[Andre55432]

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This research seems promising, what do you think?

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[trents]

So it looks like the study is in the formative stages of trial and there are no results to report yet. Am I missing something?

Hard to get excited about this until we see some testing results. There have been a number of Celiac oral prophylactics tested over the past several years that seemed promising but turned out to not be the ticket we were looking for. Orally administered solutions seem to have too many variables to make them reliable. One of the issues is timing. You have to take them at the right time before incidental exposure to gluten so that the antidote mixes properly with the food in the gut. Another is dosage amount relative to the amount of gluten to be encountered. And how do you predict that? If? When? How much? 

A more promising approach IMO is subcutaneous injections because they are more systemic in nature and therefore likely to more consistent. It would be like allergy shots or insulin injections that can be self-administered. Last week I posted links to one such study in the late stages of testing that looks very promising.

With any of these medication solutions however, there will be the question of cost and insurance coverage.