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Celiac.com Article: Risk of Autoimmune Disorders in Treated Celiac Disease Patients


Jefferson Adams

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    • Yaya
      I take all vitamins and supplements.  My cardiologist has me taking B12 5,000 once per weeks.  He gives me complete blood work every 6 months.  He's still building my D levels which is now in 60s.  He wants them in low 80s.  I take 5,000 IU's daily.  With this dosage I've gone from 42 to 65 over a period of about 5 years.  It builds very slowly.   As far as iron, I take a double dose of gentle iron with C on an empty stomach on alternate nights.  Yes, iron is a component for many of us with RLS, but mostly "brain iron" that in some people may require iron transfusions.   
    • trents
      The positive DGP-IGA indicates the possibility of celiac disease. It is typical for someone who does have celiac disease to have some antibody tests be negative and others positive. This is not unique to celiac disease diagnosis. It is why doctors typically run many tests when seeking diagnosis of a suspected disease.  The DGP-IgA test is considered to have high sensitivity and specificity. In general, the DGP-IgA test has been reported to have a sensitivity ranging from 75% to 95% and a specificity ranging from 90% to 100%. Overall, the DGP tests, including DGP-IgA and DGP-IgG, exhibit a sensitivity of approximately 85-95% and a specificity of about 95-98%. The above paragraph is taken from this article which gives an overview of the various tests that can be run for celiac disease and their reliability: What symptoms are you experiencing?
    • trents
      Check Costco's store brand.
    • trents
      Yes, get serum antibody testing done for celiac disease. You could also have NCGS (Non Celiac Gluten Sensitivity). NCGS shares many of the same symptoms of celiac disease but does not damage the lining of the small bowel as does celiac disease. There is no test for it. A diagnosis for NCGS depends on first ruling out celiac disease. It is 10x more common than celiac disease. Some experts feel it can be a precursor to the development of celiac disease. Eliminating gluten from your life is the antidote for both.
    • trents
      Biopsy results can be negative despite positive serum antibody results for these reasons: 1. Early onset of celiac disease. Inflammation has been happening for long enough to cause damage to the small bowel lining that is observable in the biopsy sample. 2. The damage is in the part of the small bowel lining below the duodenum. The duodenum is the part of the small bowel immediately below the outlet of the stomach. 3. The damage is patchy and was missed by the one doing the biopsy. A thorough biopsy would include several samples taken from different areas of the duodenum. Not all scoping is done this thoroughly, unfortunately. 4. The positive serum antibody results are caused by some other medical problem, food or medication that mimics the inflammatory reaction typical of celiac disease.
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