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Seven year old low positive iga ttg

Nik84
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Nik84 Newbie
Nik84
Posted

Hi.

my son has been really unwell for around a month now with bouts of vomiting and diarrhoea. Then a flu type thing. Doctor ordered blood tests and ultrasound. Came back low positive and really low iron level and his ultrasound showed enlarged lymph nodes.

Doctor has suggested we wait two to three months and test again? Is this normal or should I be pushing for a second opinion? He is just not well, and I’m not sure if there’s just a chance that it’s a passing thing?

Thanks ? 

 

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cyclinglady Grand Master
cyclinglady
Posted

If he had a low positive on the TTG IgA and he has a low iron level, you should see a Gastroenterologist for further evaluation.  Anemia (low iron) is common in celiacs.  I would not wait three more months.  Why make your son suffer?  Get another opinion is my best advice.  

Ennis-TX Grand Master
Ennis-TX
Posted

Just be sure he keeps eating gluten daily for the testing at least 2 slices of bread. The blood testing requires this for 8-12 weeks to be accurate and the scope with biopsies from the GI will need this for 2 weeks.

 

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    • trents
      Awaiting diagnosis

      By trents · Posted

      I would ask for a total IGA test (aka, Immunoglobulin A (IgA) and other names as well) to check for IGA deficiency. That test should always be ordered along with the TTG IGA. If someone is IGA deficient, their individual celiac IGA test scores will be artificially low which can result in false negatives. Make sure you are eating generous amounts of gluten leading up to any testing or diagnostic procedure for celiac disease to ensure validity of the results. 10g of gluten daily for a period of at least 2 weeks is what current guidelines are recommending. That's the amount of gluten found in about 4-6 slices of wheat bread.
    • jlp1999
      Awaiting diagnosis

      By jlp1999 · Posted

      There was not a total IGA test done, those were the only two ordered. I would say I was consuming a normal amount of gluten, I am not a huge bread or baked goods eater
    • trents
      Awaiting diagnosis

      By trents · Posted

      Were you consuming generous amounts of gluten in the weeks leading up to the blood draw for the antibody testing? And was there a Total IGA test done to test for IGA deficiency?
    • jlp1999
      Awaiting diagnosis

      By jlp1999 · Posted

      Thank you for the reply. It was the TTG IGA that was within normal limits
    • trents
      Awaiting diagnosis

      By trents · Posted

      Welcome to the forum, @jlp1999! Which IGA test do you refer to as being normal? TTG-IGA? Total IGA? DGP-IGA? Yes, any positive on an IGA or an IGG test can be due to something other than celiac disease and this is especially true of weak positives. Villous atrophy can also be cause by other things besides celiac disease such as some medications, parasitic infections and even some foods (especially dairy from an intolerance to the dairy protein casein). But the likelihood of that being the case is much less than it being caused by celiac disease.
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