Jump to content
This site uses cookies. Continued use is acceptance of our Terms of Use and Privacy Policy. More Info... ×

  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.



  • Celiac.com Sponsor (A1):

    Celiac.com Sponsor (A1-M):

  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Low TTG IGA but high TTG IGG

Cal4802
 Share

Recommended Posts

Cal4802 Rookie
Cal4802
Posted

Hi, 

Does anyone have any experience with having a low TTG IGA test (but not "deficient")... 1.. Over 4 was positive on scale they used... But my TTG IGG was really high (10...anything over 6 was "positive"). 

 

My understanding is TTG IGA is the more accurate of the two tests but I'm wondering why my TTG IGG would be so high. My physician told me to assume I have celiac and act like I do to play it safe because the IGG was so high and without an endoscopy of small intestine could never know for sure but safe to say.. I've been doing this for a year now and feel better, I think? Just curious if others have the same results..? 

Link to comment
Share on other sites
Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


cyclinglady Grand Master
cyclinglady
Posted

Try using the search box located at the top.  Lots of members have discussed this.   Just type in TTG IgG.  

I am sorry that you are doubting your diagnosis.  The blood tests are pretty good, but most celiac disease specialists like take a look inside your small intestine.  An endoscopy is still the gold standard in diagnosing celiac disease.

You have been gluten-free for a year.  Has your doctor re-checked to see if the TTG IgG came down?  That would be a place to start.  

Link to comment
Share on other sites
Cal4802 Rookie
Cal4802
  • Author
Posted
4 minutes ago, cyclinglady said:

Try using the search box located at the top.  Lots of members have discussed this.   Just type in TTG IgG.  

I am sorry that you are doubting your diagnosis.  The blood tests are pretty good, but most celiac disease specialists like take a look inside your small intestine.  An endoscopy is still the gold standard in diagnosing celiac disease.

You have been gluten-free for a year.  Has your doctor re-checked to see if the TTG IgG came down?  That would be a place to start.  

Thanks. Yes I've read through a lot of the other posts on the topic but nothing seems super clear. I just got retested actually so we'll see how those results come back. 

Link to comment
Share on other sites
cyclinglady Grand Master
cyclinglady
Posted

It is an unclear result.  It is not common.  Did you get tested for an IgA (Immunoglobulin A) deficiency?   This happens to about 5 to 10 % of celiacs and in the case of celiac disease testing means the IgA type tests will not work.  It is why the IgG tests are offered.  

Personally, I test positive to only the DGP IgA even in many follow-up tests, yet I had some severe intestinal damage.  I also had some risk factors like Hashimoto’s Thyroiditis and iron-deficiency anemia.  

Link to comment
Share on other sites
Cal4802 Rookie
Cal4802
  • Author
Posted
5 minutes ago, cyclinglady said:

It is an unclear result.  It is not common.  Did you get tested for an IgA (Immunoglobulin A) deficiency?   This happens to about 5 to 10 % of celiacs and in the case of celiac disease testing means the IgA type tests will not work.  It is why the IgG tests are offered.  

Personally, I test positive to only the DGP IgA even in many follow-up tests, yet I had some severe intestinal damage.  I also had some risk factors like Hashimoto’s Thyroiditis and iron-deficiency anemia.  

Interesting.. Yes they did test for IGA and it was "5" (20 or higher was "positive") but pretty sure I asked and they said I didn't have a "deficiency". So I guess I'm just like a lot of people who seem to have a high IGG but not IGA... Which might be gluten sensitivity or celiac? Probably is per my practitioner but again other things I read says who knows... 

Link to comment
Share on other sites
cyclinglady Grand Master
cyclinglady
Posted

While I have  a firm diagnosis, my hubby does not.  He went gluten-free 12 years before me per the advice of his GP and my allergist.  The diet worked.  It is obvious to everyone that gluten makes him sick.  He refuses to do a gluten challenge.  

I guess I am trying to say that if you feel good on the diet, then stick with it.  If you are not getting family support or you are still ill, you should consult with a GI who is celiac savvy.  

Link to comment
Share on other sites

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!

Register a new account

Sign in

Already have an account? Sign in here.

Sign In Now
 Share
Go to topic listing
  • Celiac.com Sponsor (A19):


  • Member Statistics

    • Total Members
      124,676
    • Most Online (within 30 mins)
      7,748
    LittleSuzysBBQ
    Newest Member
    LittleSuzysBBQ
    Joined
  • Celiac.com Sponsor (A20):

  • Forum Statistics

    • Total Topics
      120.7k
    • Total Posts
      1m
  • Celiac.com Sponsor (A22):



  • Celiac.com Sponsor (A21):


  • Upcoming Events

  • Posts

    • Scott Adams
      Seeking Advice about Fecal Transplant to Treat Celiac Disease

      By Scott Adams · Posted

      SIBO is a common secondary issue in people with untreated celiac disease. Articles in this category cover this: https://www.celiac.com/celiac-disease/celiac-disease-amp-related-diseases-and-disorders/bacterial-overgrowth-and-celiac-disease/
    • Scott Adams
      Extreme bloating even gluten-free

      By Scott Adams · Posted

      Many people with celiac disease, especially those who are in the 0-2 year range of their recovery, have additional food intolerance issues which could be temporary. To figure this out you may need to keep a food diary and do an elimination diet over a few months. Some common food intolerance issues are dairy/casein, eggs, corn, oats, and soy. The good news is that after your gut heals (for most people who are 100% gluten-free this will take several months to two years) you may be able to slowly add some these items back into your diet after the damaged villi heal, although some people may need to permanently eliminate certain foods. The two main ones to eliminate would be dairy/casein and oats.  
    • Hopeful1950
      Metabolic Meals delivery service

      By Hopeful1950 · Posted

      I am considering using the Metabolic Meals delivery service. They claim to be 100% gluten free. Has anybody used this service? If so, have you had any reactions? Is the food worth the price? Thanks, any input is appreciated
    • Wheatwacked
      Extreme bloating even gluten-free

      By Wheatwacked · Posted

      If you are looking for a good diet to follow to start your real recovery Dr Fuhrman's Eat to Live, 6 Week Plan is a good choice. Dr. Fuhrman’s 6-Week Nutritarian Diet Quick Start Dr Fuhrman is a Cardiologist who began the Nutritarian diet.  Helped me immensely with understanding nutrition.  Adapt it to GFD. If you can find them Drs Fuhrman, Amen, Davis and Hyman all had recurring annual specials on South Florida Public Service TV.
    • MaximilianKohler
      Seeking Advice about Fecal Transplant to Treat Celiac Disease

      By MaximilianKohler · Posted

      First of all, you should read this information about SIBO:  https://humanmicrobiome.info/sibo/ It's a very questionable diagnosis that leads many people to harm themselves with misguided treatments. Regarding celiac, I think it's very likely that FMT can treat it. Have a look through the related research: https://humanmicrobiome.info/intro/#celiac. You will see that multiple studies have shown that "gluten intolerance" is actually intolerance to various other "prebiotic" substances. FMT should be able to restore the microbes required to properly digest/process those prebiotic substances. The main issue I've come across is that stool donors who are good enough to treat or cure any condition are extremely rare. FYI, there is no such thing as "resetting your microbiome". Antibiotics are often the suggestion for this, but they do permanent damage that FMT may not even be able to reverse. FMT is still in the research phase, so I'd be very weary of any doctor claiming to specialize in FMT. Most of the clinical trials are using low-quality donors and getting poor results because of that.   The gut microbiome plays a major role in regulating the immune system: https://humanmicrobiome.info/immune-system/ Furthermore, the gut microbiome also regulates intestinal permeability. And in many cases, it's a permeable gut barrier that allows various particles and microbes to enter the bloodstream, which then triggers an immune reaction.
×
×
  • Create New...