Cannibinoid Hyperemesis syndrome and celiac

[MisterSeth]

I just recently came across CHS, it actually explains the symptoms I had which caused me to see the doctor in the first place. I've been a cannabis user for about 10 years and I guess long term use of THC specifically causes stomach issues. I didn't mention my cannabis use to doctor out of fear of being treated like a drug addict and just told to go to NA. (a doctor did that to me once)

I got a blood test thinking i had anemia and they found the -TtG was at 138. 

What I'm kind of wondering is if there is anyone else who suspects THC may have triggered or worsened their gluten sensetivity?

[cyclinglady]

Wow, Seth.  I am sorry to hear about your issues with CHS.  I have never  heard of it.  I did a quick google and found this heart breaking story:  

https://www.medicalnewstoday.com/articles/326357

I wonder why no one talks about this side effect.  Here in California, it is legal to use it.  I bet most people think it is safe.  ?

Not sure if marijuana usage can trigger celiac disease.  

[knitty kitty]

Hi, MisterSeth and Cycling Lady,

I googled this, too, and I found these....

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6741376/

And...

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4699997/

The scientists have found a link between CHS and Thiamine deficiency!  They don't know which comes first, like the chicken and the egg.  But some connection is there.

Thiamine deficiency is associated with high caloric malnutrition, which occurs when a person does not have enough thiamine to process all the carbohydrates consumed.  (Darn those munchies!)  It's called Gastrointestinal Beriberi.  

Thiamine deficiency can also affect the brain, Wernicke's Encephalopathy.  It's very scary.  

CHECK WITH YOUR DOCTOR.  Thiamine supplementation maybe helpful to you.  Celiac Disease causes malabsorption of essential vitamins like thiamine.

Thiamine is Vitamin B1.  It is water soluble and cannot be stored more than twenty days.  During illness or strenuous exercise, the metabolic need increases, using up those stores. The first symptoms of thiamine deficiency are nausea and vomiting.  

This syndrome is so new, more research is needed.  I hope the word  gets out to doctors about this and it's connection with thiamine.

Hope this helps!

[MisterSeth]

10 hours ago, cyclinglady said:

Wow, Seth.  I am sorry to hear about your issues with CHS.  I have never  heard of it.  I did a quick google and found this heart breaking story:  

https://www.medicalnewstoday.com/articles/326357

I wonder why no one talks about this side effect.  Here in California, it is legal to use it.  I bet most people think it is safe.  ?

Not sure if marijuana usage can trigger celiac disease.  

Yeah I came across it out of a complete fluke. I had some edibles and they made my mouth numb like i was allergic or something. I googled whether it was normal for THC to numb your mouth and found some "how can marijuana effect your stomach" article and that's how I found out this was a thing.

It's really hard to catch because long term THC users probably have vivid memories of all the times it alleviated pain. That's why I'm trying to spread awareness, people need to know to take it easy on the weed or its not going to be fun anymore

[MisterSeth]

9 hours ago, knitty kitty said:

Hi, MisterSeth and Cycling Lady,

I googled this, too, and I found these....

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6741376/

And...

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4699997/

The scientists have found a link between CHS and Thiamine deficiency!  They don't know which comes first, like the chicken and the egg.  But some connection is there.

Thiamine deficiency is associated with high caloric malnutrition, which occurs when a person does not have enough thiamine to process all the carbohydrates consumed.  (Darn those munchies!)  It's called Gastrointestinal Beriberi.  

Thiamine deficiency can also affect the brain, Wernicke's Encephalopathy.  It's very scary.  

CHECK WITH YOUR DOCTOR.  Thiamine supplementation maybe helpful to you.  Celiac Disease causes malabsorption of essential vitamins like thiamine.

Thiamine is Vitamin B1.  It is water soluble and cannot be stored more than twenty days.  During illness or strenuous exercise, the metabolic need increases, using up those stores. The first symptoms of thiamine deficiency are nausea and vomiting.  

This syndrome is so new, more research is needed.  I hope the word  gets out to doctors about this and it's connection with thiamine.

Hope this helps!

i'm already supplementing B complex. but the thiamine deficiency explains some experiences I had in the past

[knitty kitty]

The World Health Organization has a field test to quickly tell if a person is deficient in thiamine.  Can you rise from a squat?  

I squatted down in a grocery store to get an item on the bottom shelf.  I could not stand up again.  Going down into the squat was not a problem.  But I could not straighten up into a stand.  My muscles would not work.  It was creepy.  But it's one way to tell if you're deficient.

"Judged from the results of this study, the recommended intake for the adult human of 0.40 mg of thiamin per 1000 kcal by FAO/WHO and the recommended allowance of 0.5 mg per 1000 kcal by the Food and Nutrition Board of the NAS-NRC appear reasonable and amply allow for biological variations and other factors that may influence the requirement for this vitamin."

https://www.ncbi.nlm.nih.gov/pubmed/495541

The RDA is listed as 1.2 mg but that might not be enough.....

https://ods.od.nih.gov/factsheets/Thiamin-HealthProfessional/

Exercise increases the amount of thiamine and its buddy vitamins (B6 and B2) needed....

https://academic.oup.com/ajcn/article/72/2/598S/4729690

And illness can increase the need for thiamine...

https://www.healthline.com/nutrition/thiamine-deficiency-symptoms#section12

And...

https://www.hormonesmatter.com/beriberi-thiamine-deficiency-america/

Remember to talk to your doctor or nutritionist about supplementing with thiamine...

Thiamine is water soluble, so any excess is excreted.  

Another symptom of thiamine deficiency is shortness of breath because fluid collects in the lungs.  I wonder if thiamine would help the corona virus patients on respirators.....

https://www.ncbi.nlm.nih.gov/pubmed/27498674

Hope this helps!

Stay well.  Stay home.

 

 

 

27 minutes ago, MisterSeth said:

i'm already supplementing B complex. but the thiamine deficiency explains some experiences I had in the past

 

[MisterSeth]

I can rise from squats right now but after a day at work i have weakness all over. it felt like low blood sugar or something so i ate candy. guess if you need b vitamins to metabolize sugar i might have started a vicious cycle

[knitty kitty]

Yes, you could have.  

Cycling Lady often suggests buying a cheaper glucose meter.  I'm Type Two Diabetic.  Diabetics need at least 25% more thiamine than non-diabetics.  

Keeping track of your blood glucose levels when you feel weak all over like you described can help you discern if it is low blood sugar or not.  You could write your glucose readings in a food/mood/poo'd journal.  

Hope this helps! 

 

 

[MisterSeth]

1 hour ago, knitty kitty said:

Yes, you could have.  

Cycling Lady often suggests buying a cheaper glucose meter.  I'm Type Two Diabetic.  Diabetics need at least 25% more thiamine than non-diabetics.  

Keeping track of your blood glucose levels when you feel weak all over like you described can help you discern if it is low blood sugar or not.  You could write your glucose readings in a food/mood/poo'd journal.  

Hope this helps! 

 

 

definitely more worried about anorexia than diabetes on my side

[MisterSeth]

vitamin D and magnesium helped. still not sure if i need to be taking magnesium but i had calcium nodes and heard magnesium is the bodies counterbalance to calcium

[Awol cast iron stomach]

"I've been a cannabis user for about 10 years and I guess long term use of THC specifically causes stomach issues."

I am sorry for your struggles and frustration. On my part I can share I had issues stomach, gluten, and other food intolerances that I know we're not caused by THC/marijuana usage. I had never used recreational marijuana prior to diagnosis ( or any of my other prior misdiagnosis) as our state only recently went legal.

As a college code and young adult I did not experiment as it was illegal in our state.  My undergraduate degree is in biology so in college I tended to think more about things than other coeds in terms of health, biochemistry, physiology etc. I did not impart my thoughts on others. I just did not partake when offfered. I was not exposed /offered prior to college age. In fact in college in a communications class I was assigned to a debate project as the anti recreational /legal side.

Ironically as I have aged I am more relaxed about adults using legal recreational then my younger self.  Perhaps it is as states move  to make it legal. I am more open to read the research or read why some people feel it is helpful. 

So in conclusion my gi stomach issues etc in my personal circumstances are not related or caused by prior recreational marijuana use.

Best of luck to you.

 

 

Edited April 10, 2020 by Awol cast iron stomach
Autocorrect incorrect

[Mathew]

On 4/6/2020 at 3:49 PM, knitty kitty said:

The World Health Organization has a field test to quickly tell if a person is deficient in thiamine.  Can you rise from a squat?  

I squatted down in a grocery store to get an item on the bottom shelf.  I could not stand up again.  Going down into the squat was not a problem.  But I could not straighten up into a stand.  My muscles would not work.  It was creepy.  But it's one way to tell if you're deficient.

"Judged from the results of this study, the recommended intake for the adult human of 0.40 mg of thiamin per 1000 kcal by FAO/WHO and the recommended allowance of 0.5 mg per 1000 kcal by the Food and Nutrition Board of the NAS-NRC appear reasonable and amply allow for biological variations and other factors that may influence the requirement for this vitamin."

https://www.ncbi.nlm.nih.gov/pubmed/495541

The RDA is listed as 1.2 mg but that might not be enough.....

https://ods.od.nih.gov/factsheets/Thiamin-HealthProfessional/

Exercise increases the amount of thiamine and its buddy vitamins (B6 and B2) needed....

https://academic.oup.com/ajcn/article/72/2/598S/4729690

And illness can increase the need for thiamine...

https://www.healthline.com/nutrition/thiamine-deficiency-symptoms#section12

And...

https://www.hormonesmatter.com/beriberi-thiamine-deficiency-america/

Remember to talk to your doctor or nutritionist about supplementing with thiamine...

Thiamine is water soluble, so any excess is excreted.  

Another symptom of thiamine deficiency is shortness of breath because fluid collects in the lungs.  I wonder if thiamine would help the corona virus patients on respirators.....

https://www.ncbi.nlm.nih.gov/pubmed/27498674

Hope this helps!

Stay well.  Stay home.

 

 

 

 

Great bit of research this