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What Is The Difference Between Celiac & Gluten Intolerance?


skurtz

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skurtz Explorer

What is the difference between celiac & gluten intolerance? And do many people also have a problem with

candida (yeast). Also does lactose intolerance really improve when being on gluten free diet?


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lonewolf Collaborator
What is the difference between celiac & gluten intolerance? And do many people also have a problem with

candida (yeast). Also does lactose intolerance really improve when being on gluten free diet?

I'm probably not going to be much help, since I'm still trying to figure out the difference. I tested negative for the 2 main Celiac genes, so my doctor said that I definitely DON'T have Celiac. But I have symptoms very similar to people here who have been officially diagnosed and have experienced great health improvements with a gluten-free diet. So my doctor said that I am gluten intolerant and stick with the gluten-free diet. Either way, you need to be gluten-free. There has been some discussion on this board in the past that people with true Celiac Disease have damage to the villi and people with gluten intolerance have all the same symptoms without the damage. I don't think anyone knows for sure. I have had problems with candida too and have seen lots of posts from people stating the same. As for the lactose intolerance, I can't tell you because I can't do dairy at all.

Good luck!

zip2play Apprentice
There has been some discussion on this board in the past that people with true Celiac Disease have damage to the villi and people with gluten intolerance have all the same symptoms without the damage.

This is how it was described to me by Dana Korn. I don't have villi damage, but I am certain I am gluten intolerant!

Monica

tiredofdoctors Enthusiast

I have gluten intolerance, but I have "autoimmune cerebellar disease" or they also call it "gluten ataxia". Instead of having celiac symptoms, the antigliadin antibodies cross-react with anti-perkinje cell antibodies which I also produce -- working to destroy the perkinje cells. Unfortunately, they don't regenerate, and they're in the cerebellum of my brain, my retinas and my peripheral nerves.

Guest nini

There is no difference between Celiac and Gluten Intolerance. They are the same thing. Celiac just means that the villi are damaged and can't absorb nutrients. Gluten Intolerance is simply a precursor to Celiac. Some people with Gluten Intolerance will never develop full blown Celiac, but All Celiacs have Gluten Intolerance. I believe I remember the Celiac Expert that spoke at our support group meeting said that she believes that Gluten Intolerance could be early Celiac.

Do you want to wait until your villi are completely gone and your health in shatters before you go gluten free? no, Then technically, does it matter if it's Celiac or Gluten Intolerance? The treatment is the same.

CMCM Rising Star

I swiped this from the Enterolab information section:

WHAT IS THE DIFFERENCE BETWEEN CELIAC SPRUE & GLUTEN SENSITIVITY?

Gluten sensitivity implies that a person's immune system is intolerant of gluten in the diet and is forming antibodies or displaying some other evidence of an inflammatory reaction. When these reactions cause small intestinal damage visible on a biopsy, the syndrome has been called celiac sprue, celiac disease, or gluten sensitive enteropathy. (Nontropical sprue and idiopathic steatorrhea are other terms that have been used for this disorder in the past.) The clinical definition of celiac sprue also usually requires that there is clinical and/or pathologic improvement following a gluten-free diet.

In the past, celiac sprue could only be diagnosed after somebody developed certain symptoms like diarrhea, weight loss, or growth failure in children. A biopsy would be performed and if abnormal and typical of celiac sprue, and if a gluten free diet brought resolution of diarrhea, weight gain, or growth, only then would a diagnosis of celiac sprue be made. However, recent advances in diagnostic screening tests and application of these tests to people at heightened risk or to general populations have allowed detection of celiac sprue, sometimes even before damage to villi has occurred. This latter scenario is often called gluten sensitivity.

CAN I HAVE GLUTEN SENSITIVITY IF SMALL INTESTINAL BIOPSIES ARE NORMAL OR ONLY MINIMALLY ABNORMAL?

Although by definition a normal small bowel biopsy rules out celiac sprue, it does not rule out gluten sensitivity. Although asymptomatic people with gluten sensitivity may have normal or near-normal biopsies, so too may people with symptomatic gluten sensitivity. This has been reported in the medical literature (called "Gluten Sensitivity with minimal Enteropathy" or "Gluten-Sensitive Diarrhea without Celiac Disease". Furthermore, even though such people's intestines appear normal under the microscope, up to one half already have nutrient malabsorption, a major contributor to osteoporosis and malnutrition, attesting to the fact that microscopic analysis of intestinal biopsies is an insensitive way of assessing function and immunologic food sensitivity. However, because there is still a virtually universal reliance on small bowel biopsies to diagnose gluten intolerance, most asymptomatic or symptomatic gluten sensitive people (based on screening tests) will not be diagnosed correctly or be instructed to follow a gluten-free diet even though symptoms may resolve completely.

WHO SHOULD BE SCREENED FOR GLUTEN SENSITIVITY?

Because research has shown that as many as 30% of all Americans may be gluten sensitive, and that 1 in 225 have a severe form of this sensitivity causing the intestinal disease called celiac sprue, a case can be made that everyone in America should be screened for gluten sensitivity. However, there are people with various risk factors or diseases that are at greater risk of developing gluten sensitivity who should undoubtedly be tested.

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    • Scott Adams
      This is a very common question, and the most important thing to know is that no, Guinness is not considered safe for individuals with coeliac disease. While it's fascinating to hear anecdotes from other coeliacs who can drink it without immediate issues, this is a risky exception rather than the rule. The core issue is that Guinness is brewed from barley, which contains gluten, and the standard brewing process does not remove the gluten protein to a level safe for coeliacs (below 20ppm). For someone like you who experiences dermatitis herpetiformis, the reaction is particularly significant. DH is triggered by gluten ingestion, even without immediate gastrointestinal symptoms. So, while you may not feel an instant stomach upset, drinking a gluten-containing beer like Guinness could very well provoke a flare-up of your skin condition days later. It would be a gamble with a potentially uncomfortable and long-lasting consequence. Fortunately, there are excellent, certified gluten-free stouts available now that can provide a safe and satisfying alternative without the risk.
    • MogwaiStripe
      Interestingly, this thought occurred to me last night. I did find that there are studies investigating whether vitamin D deficiency can actually trigger celiac disease.  Source: National Institutes of Health https://pmc.ncbi.nlm.nih.gov/articles/PMC7231074/ 
    • Butch68
      Before being diagnosed coeliac I used to love Guinness. Being made from barley it should be something a coeliac shouldn’t drink. But taking to another coeliac and they can drink it with no ill effects and have heard of others who can drink it too.  is this everyone’s experience?  Can I drink it?  I get dermatitis herpetiformis and don’t get instant reactions to gluten so can’t try it to see for myself. 
    • trents
      NCGS does not cause damage to the small bowel villi so, if indeed you were not skimping on gluten when you had the antibody blood testing done, it is likely you have celiac disease.
    • Scott Adams
      I will assume you did the gluten challenge properly and were eating a lot of gluten daily for 6-8 weeks before your test, but if not, that could be the issue. You can still have celiac disease with negative blood test results, although it's not as common:  Clinical and genetic profile of patients with seronegative coeliac disease: the natural history and response to gluten-free diet: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5606118/  Seronegative Celiac Disease - A Challenging Case: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9441776/  Enteropathies with villous atrophy but negative coeliac serology in adults: current issues: https://pubmed.ncbi.nlm.nih.gov/34764141/  Approximately 10x more people have non-celiac gluten sensitivity than have celiac disease, but there isn’t yet a test for NCGS. If your symptoms go away on a gluten-free diet it would likely signal NCGS.
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