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What Is The Difference Between Celiac & Gluten Intolerance?


skurtz

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skurtz Explorer

What is the difference between celiac & gluten intolerance? And do many people also have a problem with

candida (yeast). Also does lactose intolerance really improve when being on gluten free diet?


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lonewolf Collaborator
What is the difference between celiac & gluten intolerance? And do many people also have a problem with

candida (yeast). Also does lactose intolerance really improve when being on gluten free diet?

I'm probably not going to be much help, since I'm still trying to figure out the difference. I tested negative for the 2 main Celiac genes, so my doctor said that I definitely DON'T have Celiac. But I have symptoms very similar to people here who have been officially diagnosed and have experienced great health improvements with a gluten-free diet. So my doctor said that I am gluten intolerant and stick with the gluten-free diet. Either way, you need to be gluten-free. There has been some discussion on this board in the past that people with true Celiac Disease have damage to the villi and people with gluten intolerance have all the same symptoms without the damage. I don't think anyone knows for sure. I have had problems with candida too and have seen lots of posts from people stating the same. As for the lactose intolerance, I can't tell you because I can't do dairy at all.

Good luck!

zip2play Apprentice
There has been some discussion on this board in the past that people with true Celiac Disease have damage to the villi and people with gluten intolerance have all the same symptoms without the damage.

This is how it was described to me by Dana Korn. I don't have villi damage, but I am certain I am gluten intolerant!

Monica

tiredofdoctors Enthusiast

I have gluten intolerance, but I have "autoimmune cerebellar disease" or they also call it "gluten ataxia". Instead of having celiac symptoms, the antigliadin antibodies cross-react with anti-perkinje cell antibodies which I also produce -- working to destroy the perkinje cells. Unfortunately, they don't regenerate, and they're in the cerebellum of my brain, my retinas and my peripheral nerves.

Guest nini

There is no difference between Celiac and Gluten Intolerance. They are the same thing. Celiac just means that the villi are damaged and can't absorb nutrients. Gluten Intolerance is simply a precursor to Celiac. Some people with Gluten Intolerance will never develop full blown Celiac, but All Celiacs have Gluten Intolerance. I believe I remember the Celiac Expert that spoke at our support group meeting said that she believes that Gluten Intolerance could be early Celiac.

Do you want to wait until your villi are completely gone and your health in shatters before you go gluten free? no, Then technically, does it matter if it's Celiac or Gluten Intolerance? The treatment is the same.

CMCM Rising Star

I swiped this from the Enterolab information section:

WHAT IS THE DIFFERENCE BETWEEN CELIAC SPRUE & GLUTEN SENSITIVITY?

Gluten sensitivity implies that a person's immune system is intolerant of gluten in the diet and is forming antibodies or displaying some other evidence of an inflammatory reaction. When these reactions cause small intestinal damage visible on a biopsy, the syndrome has been called celiac sprue, celiac disease, or gluten sensitive enteropathy. (Nontropical sprue and idiopathic steatorrhea are other terms that have been used for this disorder in the past.) The clinical definition of celiac sprue also usually requires that there is clinical and/or pathologic improvement following a gluten-free diet.

In the past, celiac sprue could only be diagnosed after somebody developed certain symptoms like diarrhea, weight loss, or growth failure in children. A biopsy would be performed and if abnormal and typical of celiac sprue, and if a gluten free diet brought resolution of diarrhea, weight gain, or growth, only then would a diagnosis of celiac sprue be made. However, recent advances in diagnostic screening tests and application of these tests to people at heightened risk or to general populations have allowed detection of celiac sprue, sometimes even before damage to villi has occurred. This latter scenario is often called gluten sensitivity.

CAN I HAVE GLUTEN SENSITIVITY IF SMALL INTESTINAL BIOPSIES ARE NORMAL OR ONLY MINIMALLY ABNORMAL?

Although by definition a normal small bowel biopsy rules out celiac sprue, it does not rule out gluten sensitivity. Although asymptomatic people with gluten sensitivity may have normal or near-normal biopsies, so too may people with symptomatic gluten sensitivity. This has been reported in the medical literature (called "Gluten Sensitivity with minimal Enteropathy" or "Gluten-Sensitive Diarrhea without Celiac Disease". Furthermore, even though such people's intestines appear normal under the microscope, up to one half already have nutrient malabsorption, a major contributor to osteoporosis and malnutrition, attesting to the fact that microscopic analysis of intestinal biopsies is an insensitive way of assessing function and immunologic food sensitivity. However, because there is still a virtually universal reliance on small bowel biopsies to diagnose gluten intolerance, most asymptomatic or symptomatic gluten sensitive people (based on screening tests) will not be diagnosed correctly or be instructed to follow a gluten-free diet even though symptoms may resolve completely.

WHO SHOULD BE SCREENED FOR GLUTEN SENSITIVITY?

Because research has shown that as many as 30% of all Americans may be gluten sensitive, and that 1 in 225 have a severe form of this sensitivity causing the intestinal disease called celiac sprue, a case can be made that everyone in America should be screened for gluten sensitivity. However, there are people with various risk factors or diseases that are at greater risk of developing gluten sensitivity who should undoubtedly be tested.

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    • trents
      Thanks for the thoughtful reply and links, Wheatwacked. Definitely some food for thought. However, I would point out that your linked articles refer to gliadin in human breast milk, not cow's milk. And although it might seem reasonable to conclude it would work the same way in cows, that is not necessarily the case. Studies seem to indicate otherwise. Studies also indicate the amount of gliadin in human breast milk is miniscule and unlikely to cause reactions:  https://www.glutenfreewatchdog.org/news/gluten-peptides-in-human-breast-milk-implications-for-cows-milk/ I would also point out that Dr. Peter Osborne's doctorate is in chiropractic medicine, though he also has studied and, I believe, holds some sort of certifications in nutritional science. To put it plainly, he is considered by many qualified medical and nutritional professionals to be on the fringe of quackery. But he has a dedicated and rabid following, nonetheless.
    • Scott Adams
      I'd be very cautious about accepting these claims without robust evidence. The hypothesis requires a chain of biologically unlikely events: Gluten/gliadin survives the cow's rumen and entire digestive system intact. It is then absorbed whole into the cow's bloodstream. It bypasses the cow's immune system and liver. It is then secreted, still intact and immunogenic, into the milk. The cow's digestive system is designed to break down proteins, not transfer them whole into milk. This is not a recognized pathway in veterinary science. The provided backup shifts from cow's milk to human breastmilk, which is a classic bait-and-switch. While the transfer of food proteins in human breastmilk is a valid area of study, it doesn't validate the initial claim about commercial dairy. The use of a Dr. Osborne video is a major red flag. His entire platform is based on the idea that all grains are toxic, a view that far exceeds the established science on Celiac Disease and non-celiac gluten sensitivity. Extraordinary claims require extraordinary evidence, and a YouTube video from a known ideological source is not that evidence."  
    • Wheatwacked
      Some backup to my statement about gluten and milk. Some background.  When my son was born in 1976 he was colicky from the beginning.  When he transitioned to formula it got really bad.  That's when we found the only pediactric gastroenterologist (in a population of 6 million that dealt with Celiac Disease (and he only had 14 patients with celiac disease), who dianosed by biopsy and started him on Nutramegen.  Recovery was quick. The portion of gluten that passes through to breastmilk is called gliadin. It is the component of gluten that causes celiac disease or gluten intolerance. What are the Effects of Gluten in Breastmilk? Gliaden, a component of gluten which is typically responsible for the intestinal reaction of gluten, DOES pass through breast milk.  This is because gliaden (as one of many food proteins) passes through the lining of your small intestine into your blood. Can gluten transmit through breast milk?  
    • trents
      I don't know of a connection. Lots of people who don't have celiac disease/gluten issues get shingles.
    • Ginger38
      I’m 43, just newly diagnosed with a horrible case of shingles last week . They are all over my face , around my eye, ear , all in my scalp. Lymph nodes are a mess. Ear is a mess. My eye is hurting and sensitive. Pain has been a 10/10+ daily. Taking Motrin and Tylenol around the clock. I AM MISERABLE. The pain is unrelenting. I just want to cry.   But Developing shingles has me a bit concerned about my immune system which also has me wondering about celiac and if there’s a connection to celiac / gluten and shingles; particularly since I haven't been 💯 gluten free because of all the confusing test results and doctors advice etc., is there a connection here? I’ve never had shingles and the gluten/ celiac  roller coaster has been ongoing for a while but I’ve had gluten off and on the last year bc of all the confusion  
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