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Gluten Intolerance


lemonade

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lemonade Enthusiast

IS there a difference between Celiac Disease and Gluten Intolerance?

Lemonade


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tarnalberry Community Regular

Celiac disease is a subset of gluten intolerance. Gluten intolerance - the immune reaction to gluten - causes celiac disease - the destruction of the villi. There is evidence that you can have an immune reaction to gluten that does not lead to the classic destruction of the villi that characterizes celiac disease. (That's not to say that if you're gluten intolerant without celiac disease that you could still eat gluten, of course!)

Guest nini

in my opinion, NO, but technically, Celiac is defined by blunting of the villi... if you cannot prove blunting of the villi, then "technically" you don't have Celiac, but if gluten bothers you and causes problems and your problems get better on the gluten free diet, then you do have Celiac... or you are just gluten intolerant! either way it's the same thing... you treat it the same way. Life long adherance to the gluten free diet.

CMCM Rising Star
IS there a difference between Celiac Disease and Gluten Intolerance?

Lemonade

Some articles I've read say that many doctors would actually like to eliminate the designation "celiac disease" and call the whole thing something like "gluten intolerance" or "gluten sensitivity." These doctors consider the condition to be a spectrum of reactions, ranging from no observable symptoms (yet possible intestinal damage could still be occurring...or not!) to moderate symptoms to severe symptoms.

Some doctors, including Enterolab's Dr. Fine, say that once a diagnoses of gluten sensitivity has been made, and also if you test and have the genes, you should no longer eat gluten....the theory apparently being that if you don't have symptoms or damage going on now, you may have them later.

Going strictly gluten free for a period of time will either make you feel better or it won't. If it does make you feel better and eliminates many or most of the symptoms, it seems logical to continue a gluten free existence. Unless you like feeling bad, that is!

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    • jimmydee
      Thank you for the information Trents!  
    • robingfellow
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    • trents
      Welcome to the forum, @jimmydee! Celiac disease is an autoimmune disorder, meaning the consumption of gluten triggers a response by the immune system that causes the body to attack it's own tissue. Celiac disease has a genetic base that requires some kind of trigger for the genes to be turned on. We know that there are two primary genes responsible for providing the potential to develop celiac disease and we know that about 40% of the population carries one or both of these genes. However, only about 1% of the population actually develops celiac disease. So, that tells us that something more than just having the genes is necessary in order to develop celiac disease. Something must trigger those genes to wake up and produce the active disease. It's that "something" that we are struggling to understand and that is somewhat of a mystery. But there is a growing body of evidence pointing to the culprit being a disruption of the proper balance of microorganisms in the gut. Apparently, the microorganisms that live in our intestines produce chemicals that regulate the size of the openings in the mucous lining of our small bowel. A disruption in the healthy balance of this microorganic community causes an increase in the size of the openings in the mucous lining. This in turn allows protein fragments from the food we eat that are larger than normal to invade the mucous lining where they are detected as threats by the immune system. This is what is happening with gluten for those with celiac disease. The attack in the mucous lining of the small bowel by the immune system on these incompletely broken down gluten components causes inflammation and, over time, as we continue to consume gluten, it damages the mucosal lining of the small bowel which results in the loss of efficiency of nutrient absorption. This mucosal lining is made up of millions of tiny finger like projections that create an enormous surface area for the absorption of nutrients when healthy. The "wearing down" of these millions of finger-like projections due to celiac inflammation greatly reduces the surface area and thus the ability to absorb nutrients. This in turn typically results in numerous health issues that have a nutrient deficiency base. But the answer to the question of why there seems to be an epidemic of celiac disease in recent years may not be simple. It may have many facets. First, we don't know how much of this epidemic is real and how much is apparent. That is, how much of what we perceive of as a dramatic increase in the incidence of celiac disease is simply due to greater awareness and better detection methods? Celiac disease is not new. There is evidence from ancient writings that people suffered from it back then but they did not have a name for it. And it wasn't until WW2 that gluten was identified as the cause of celiac disease. Current thinking on what is causing imbalance in gut biology has put forth a number of causes including overuse of antibiotics and pesticides, environmental toxins, fluoridation of drinking water, preoccupation with hygiene and sanitation, and the western diet. https://www.celiac.com/celiac-disease/theories-on-the-growing-prevalence-of-celiac-disease-and-gluten-sensitivity-over-the-last-half-century-video-r6716/?tab=comments#comment-25345 All this to say that I doubt your UTI or the low dose aspirin had anything to do with the onset of your celiac disease. It was probably just coincidence unless the UTI was the stress trigger that activated the celiac potential genes. The onset of celiac disease an happen at any stage of life and many people report it following a period of illness. But what is interesting about your low dose aspirin theory is that aspirin is in a class of medications known as NSAIDs (Non Steroidal Anti Inflammatory Drugs). Scientific studies have shown that long term use of NSAIDs can damage the villous lining of the small bowel in the same way as celiac disease.  The other thing I wish to point out is that unless you have actual testing done for celiac disease, you can't be sure if you have celiac disease or NCGS (Non Celiac Gluten Sensitivity). They share many of the same symptoms, the difference being that NCGS doesn't damage the lining of the small bowel. There is no test for NCGS, celiac disease must first be ruled out. NCGS is 10x more common than celiac disease. The antidote for both is a gluten free diet.
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    • jimmydee
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