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Celiac panel results


jlollman

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jlollman Newbie

Opinions on celiac panel results:

13yr old son with stomach pain and diarrhea at least 10x a month. Will hurt and have diarrhea for about 2hrs each time. Can’t pinpoint certain foods causing it. Took to GP and she said celiac panel was probably for celiac and is referring to gastro doc. He has had previous auto immune issues with ITP but in remission after spleen removal. According to my research, his tests are not indicative of celiac? No IGA deficiency and only a weak positive on IGG and mild high immunoglobulin A serum. See attached 

iga 17

igg 26

 


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jlollman Newbie
1 minute ago, jlollman said:

Opinions on celiac panel results:

13yr old son with stomach pain and diarrhea at least 10x a month. Will hurt and have diarrhea for about 2hrs each time. Can’t pinpoint certain foods causing it. Took to GP and she said celiac panel was probably for celiac and is referring to gastro doc. He has had previous auto immune issues with ITP but in remission after spleen removal. According to my research, his tests are not indicative of celiac? No IGA deficiency and only a weak positive on IGG and mild high immunoglobulin A serum. See attached 

iga 17

igg 26

 

 

C08AFE87-A97E-46BE-B34B-017A31140D01.webp

cyclinglady Grand Master

Well, this should be discussed with your doctor.  Your son does have an usual result.  His DGP IgG is elevated slightly.  He should be referred to a GI for further evaluation.  We have had members who have tested positive to only the DGP IgG and have been confirmed celiac via endoscopy. The elevated immunoglobulin A  (IgA) could be due to any autoimmune.  But it is within range if you had used my lab.  This is used to confirm that your celiac IgA related tests are accurate and there are some celiacs who are IgA deficient (less than 10%, I think).  
 

Not a “slam dunk” diagnosis.  😥

jlollman Newbie
1 hour ago, cyclinglady said:

Well, this should be discussed with your doctor.  Your son does have an usual result.  His DGP IgG is elevated slightly.  He should be referred to a GI for further evaluation.  We have had members who have tested positive to only the DGP IgG and have been confirmed celiac via endoscopy. The elevated immunoglobulin A  (IgA) could be due to any autoimmune.  But it is within range if you had used my lab.  This is used to confirm that your celiac IgA related tests are accurate and there are some celiacs who are IgA deficient (less than 10%, I think).  
 

Not a “slam dunk” diagnosis.  😥

Thanks for the reply! They are sending him to gastro doc., so hopefully that will be negative. (Endoscopy)

GFinDC Veteran
(edited)

A weak positive is still a positive.  Along with the GI symptoms he is having it points to possible celiac disease IMHO.  An endoscopy may find proof positive in damaged small intestinal villi.  Or it may not, as the endoscopy is not a perfect tool for diagnosis.

When you say you can't pinpoint a certain food causing the GI symptoms that is not surprising.  When a person with celiac is experiencing ongoing gut damage / inflammation, their digestive process can react badly to any food.  I suggest you try eliminating dairy for a few weeks to see if the symptoms are better.  Untreated celiacs are often lactose intolerant for a while due to the villi damage.  Going dairy free won't change celiac antibody test results.  Lactose intolerance can cause diahhrea and bloating.  So going off dairy may reduce symptoms some.  A calcium supplement might be a good idea.

Another thing to look at is vitamin / mineral levels.  If they are low it could be caused by mal-absorption form celiac damage.  That can also cause short stature and tooth enamel defects.

He needs to keep eating at least some small amount of gluten each day for the testing/endoscopy to work.

Edited by GFinDC
jlollman Newbie
On 8/14/2020 at 6:04 PM, GFinDC said:

A weak positive is still a positive.  Along with the GI symptoms he is having it points to possible celiac disease IMHO.  An endoscopy may find proof positive in damaged small intestinal villi.  Or it may not, as the endoscopy is not a perfect tool for diagnosis.

When you say you can't pinpoint a certain food causing the GI symptoms that is not surprising.  When a person with celiac is experiencing ongoing gut damage / inflammation, their digestive process can react badly to any food.  I suggest you try eliminating dairy for a few weeks to see if the symptoms are better.  Untreated celiacs are often lactose intolerant for a while due to the villi damage.  Going dairy free won't change celiac antibody test results.  Lactose intolerance can cause diahhrea and bloating.  So going off dairy may reduce symptoms some.  A calcium supplement might be a good idea.

Another thing to look at is vitamin / mineral levels.  If they are low it could be caused by mal-absorption form celiac damage.  That can also cause short stature and tooth enamel defects.

He needs to keep eating at least some small amount of gluten each day for the testing/endoscopy to work.

Thanks!!

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