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Celiac.com Article:Protective Antioxidants

Melissa McLean Jory
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Melissa McLean Jory
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    • trents
      Conflicting results

      By trents · Posted

      Thanks. Now it all makes sense. So, it looks like he may be IGA deficient or on the cusp of it. So, the reliability of the tTG-IGA testing is dubious. Being that the EMA is positive, my money would be on him having celiac disease, especially with the symptoms he is experiencing. The next logical diagnostic step would be to have an endoscopy/biopsy done of the small bowel lining to check for damage. Has the physician mentioned this? Sometimes they are reluctant to do this on children. Please hear this: Before you attempt to put him on a gluten-free diet or even cut back on his gluten intake, make sure you aren't planning any more testing for celiac disease. Removing gluten from his diet will sabotage any future testing. From the way you spell "coeliac" I'm guessing you are in the UK so I realize there may be stipends and follow-up healthcare benefits available to your son if there is an official diagnosis of celiac disease. But I also understand it can take many months to get a procedure in place with the backlog in your healthcare system.
    • Scott Adams
      Conflicting results

      By Scott Adams · Posted

      It looks to me like he's IgA deficient, or borderline IgA deficient, which means that his TTg-IgA test results for celiac disease will be lower than they actually should be. His first celiac disease test was still highly positive, even though he is IgA deficient, and this is a strong indication that he has celiac disease. The fact that he's IgA deficient means that they should be doing other tests as well because the IgA-based tests won't be accurate. This article might be helpful. It breaks down each type of test, and what a positive results means in terms of the probability that you might have celiac disease. In children they should also be doing DGP-IgA and DGP-IgG (Deamidated Gliadin Peptide), and because he's IgA deficient they should include TTg-IgG.    
    • Jy11
      Conflicting results

      By Jy11 · Posted

      He has had coeliac bloods repeated three times.   Ive tried to make them clearer but wont line up properly on my phone.    1st bloods  TTg IgA6.7    Normal range <7 IgA 0.2          Normal range 0.4-2 2nd bloods  TTg IgA 2.4        Normal range <7 IgA  0.41          Normal range 0.4-2 3rd bloods  TTg IgA3.6       Normal range <7 IgA 0.54           Normal 0.5-2.4 EMA Positive      His IgA bloods are counted as normal but very close to the cut off for IgA deficient.. Apart from one where it actually was deficient 
    • Scott Adams
      Stagnating recovery

      By Scott Adams · Posted

      Many people with celiac disease, especially those who are in the 0-2 year range of their recovery, have additional food intolerance issues which could be temporary. To figure this out you may need to keep a food diary and do an elimination diet over a few months. Some common food intolerance issues are dairy/casein, eggs, corn, oats, and soy. The good news is that after your gut heals (for most people who are 100% gluten-free this will take several months to two years) you may be able to slowly add some these items back into your diet after the damaged villi heal. This article may be helpful:    
    • Scott Adams
      Conflicting results

      By Scott Adams · Posted

      I agree, is it possible that your child is IgA deficient, yet has positive results for their tTg-IgA result?
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