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Mixed Blood Work, Negative Biopsy


OliviaVan

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OliviaVan Newbie

Hello! I'm just looking for some advice.

After years of having digestive issues, bloating and fatigue my doctor tested me for celiac disease (age 26). My lab results came back with "Deamidated Gliadin peptide AB IgG: Hi Positive (42.3 U/mL) and Tissue Transglutaminase Ab IgA: Negative (4.6 U/mL). My blood work also came back with very low D and lower (but not deficient) vitamin B and Iron.

My doctor sent me to a specialist and he performed an endoscopy and colonoscopy (family history of colon cancer). He found nothing wrong and the biopsies were negative for celiac. 

My symptoms have continued and bloating in particular has worsened. I began seeing a naturopath to combat the bloating, weight gain and fatigue. After seeing my celiac panel she strongly recommended going gluten free. This has been a challenge and I don't know how strictly to follow the diet. So far I've been trying for about a month and I have noticed improvements but they could also be linked to other reasons (supplements and healthier lifestyle).

Should I stick with the gluten free diet? Should I consider getting re-tested? Without my family doctor on board everything would be out of pocket I suppose. The pandemic would make getting an appointment and tested very difficult.

Thanks! 

 


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RMJ Mentor

You could stick with the gluten free diet and have some of the blood tests redone in 6 months.  If the Deamidated gliadin peptide AB went down that would indicate that gluten was an issue for you.

Scott Adams Grand Master

I would only add that you should really put in more effort to make sure you’re 100% gluten-free. If gluten is your issue, then this is the only way to know for sure. It should relieve your symptoms.

 

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