Welcome to the forum, @Skg414228! You say that your DGP-IGA score is high and you give the absolute test score but you do not give the scale or units used by the lab doing the analysis so we cannot comment further on your conclusion. Different labs use different reference ranges for the same tests. There is no industry standard for these celiac antibody tests. So, could you also post back with the scale and the units? If you already have an endoscopy/biopsy scheduled, the important thing is to hold off on going gluten free until that is done. There are some things besides celiac disease that can cause elevated celiac disease antibody levels so it is still possible you may be looking at something else. This is especially true when you are not IGA deficient and the tTG-IGA is within normal range. But you are correct in saying that very high antibody antibody scores strongly weight the probability in favor of celiac disease. Keep us posted. By the way, kudos to your physician for ordering a more complete antibody panel. Many will only order the tTG-IGA.

I went to the gastroenterologist for what I thought was IBS. They thought it sounded like celiac. I got a blood test with normal everything except a deamidated gliadine peptide iga of 688. Total iga was in normal range so not deficient.    My question is with a dgp iga like that is it pretty much only celiac at that point. I haven’t seen anything else that would cause the dgp iga to be that high. Already have the biopsy scheduled so nothing is going to change I’m just curious what else it could be and is the number high enough that I should really be preparing expecting a positive biopsy and it’s just a confirmation at this point? 

Sometimes celiacs can also have other things like lactose intolerance which is fairly common. Also research fodmap foods, it's quite complicated but there are some other foods which can cause digestive issues. For me it's too many onions and garlic.

You may be reacting to some of the ingredients used to imitate gluten products. I eat Amy's Chilli quite often with no problems. When I eat Bush's chilli beans or Hormel Chilli with the same ingredient list, I get heartburn.  Break out the alka seltzer.   Barillo spaghetti has CORN FLOUR, RICE FLOUR, MONO AND DIGLYCERIDES. Udi's White bread Ingredients - water, tapioca starch, brown rice flour, canola oil, dried egg whites, sugar, tapioca maltodextrin, tapioca syrup, sorghum flour, less than 2% of: rice starch, sorghum grain, flaxseed meal,  gum blend (xanthan gum, sodium alginate, guar gum), apple cider vinegar, apple fiber, molasses, salt, amaranth flour, teff flour, yeast, cultured brown rice, locust bean gum, enzymes Chobani Greek Yogurt Cultured nonfat milk, cane sugar, water, natural flavors, fruit pectin, guar gum, locust bean gum, vanilla extract, lemon juice concentrate.

My TTG was 167 one year ago. Recently had it retested one month ago and it went down to 16. I only recently had an endoscopy done as I was pregnant within the last year. I did not eat gluten prior to this endoscopy as I get very sick. Prior to obtaining the biopsies, the endoscopy said “ diffuse moderately erythematous mucosa to the second part of the duodenum without bleeding.” However, the biopsy came back negative. I assume it’s a false negative as I have also had genetic testing to confirm celiac. However, what would cause the inflammation to the second part of the duodenum and continued positive blood markers if the intestines have healed?