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blood test results - waiting for doctor for Son


Metoo

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Metoo Enthusiast

I am waiting we just got the results from my son's blood test for my doctors office to get back with us.  

Do you think this looks like its positive for possibly celiac?  He has no symptoms but we recheck every 2 years on my gastros recommendation because I have it.

Tissue Transglutaminase Ab, IgA, S  0.5 U/mL   Range: 0.0 - 6.9 U/mL

Tissue Transglutaminase Ab, IgA, S Interpretation - Negative

Tissue Transglutaminase Ab, IgG, S 0.8 U/mL  Range: 0.0 - 6.9 U/mL

Tissue Transglutaminase Ab, IgG, S Interpretation - Negative

Anti-Gliadin IgA  11.0 U/mL  Range: 0.0 - 6.9 U/mL High

Anti-Gliadin IgA Interpretation - Positive Abnormal

Anti-Gliadin IgG <0.4 U/mL  Range: 0.0 - 6.9 U/mL

Anti-Gliadin IgG Interpretation - Negative


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Scott Adams Grand Master

If you have celiac disease, and it sounds like that is the case, then your son has an ~44% chance of developing it, and he does have a strong positive on this test, so I'd be concerned:

  • Anti-Gliadin IgA  11.0 U/mL  Range: 0.0 - 6.9 U/mL High
  • Anti-Gliadin IgA Interpretation - Positive Abnormal

The article below is older, but still valid, and says:

Quote

IgA anti-gliadin antibodies are less sensitive but are more specific. In clinical trials, the IgA antibodies have a specificity of 97% but the sensitivity is only 71%. That means that, if a patient is IgA positive, there is a 97% probability that they have celiac disease. Conversely, if the patient is IgA negative, there is only a 71% probability that the patient is truly negative for celiac disease. Therefore, a positive result is a strong indication that the patient has the disease but a negative result does not necessarily mean that they don not have it. False positive results are rather uncommon but false negative results can occur. 

 

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