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Blood test results


Darkside

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Darkside Rookie

I recently had Blood test done and the results was the fallowing.

Tested positive for  the IgA antibodies 

HLA-DQ2 Positive

HLA-DQ8 Negative

My internist wants to retest me to be sure the results were accurate before sending me for an endoscopy. how accurate is the bloodtest to diagnose celiac? 


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trents Grand Master

We can't tell you anything concerning your IGA test results with the information you have given us. IGA is not a test but a category including several different specific tests. Check this out: https://celiac.org/about-celiac-disease/screening-and-diagnosis/screening/ Can you list the specific tests that were run and the resulting values? We would also need reference ranges to be able to know what is considered normal or negative and what is considered positive. Different labs use different reference ranges.

You have one of the two genes that have been identified as risks for celiac disease. Having one or even both of the genes does not ensure that you have or will develop celiac disease. The genetic tests merely establish potential.

Darkside Rookie
3 hours ago, trents said:

We can't tell you anything concerning your IGA test results with the information you have given us. IGA is not a test but a category including several different specific tests. Check this out: https://celiac.org/about-celiac-disease/screening-and-diagnosis/screening/ Can you list the specific tests that were run and the resulting values? We would also need reference ranges to be able to know what is considered normal or negative and what is considered positive. Different labs use different reference ranges.

You have one of the two genes that have been identified as risks for celiac disease. Having one or even both of the genes does not ensure that you have or will develop celiac disease. The genetic tests merely establish potential.

Anti-Transglutaminase (IgA) 57.6 H S1      Reference Range U/mL [0,0-14,9]

Interp.Transglutaminase Positive A S1 R1 

trents Grand Master

Your tTG-IGA at 57.6 is strongly positive. This definitely suggests you have celiac disease. There is another diagnostic step that can be taken and that is an endoscopy with a biopsy of the small bowel lining to check for damage to the villi. This second diagnostic step is considered the gold standard of diagnosing celiac disease. If your physician wants you to have this done it is important to continue to eat regular amounts of gluten (the equivalent of two slices of wheat bread per day) up until the time of the test. You should not go on a gluten free diet until all testing is done in order for the tests to be valid.

If your physician is convinced that you have celiac disease and doesn't see a need for further testing then you need to start eating gluten free. There is a real learning curve involved with that since gluten is hidden by terminology and is often found in foods you would never suspect wheat/barley/rye to show up in. Examples, canned tomato soup and soy sauce and even some chocolate syrup products. This might help: 

 

Scott Adams Grand Master

I agree with @trents, and would only add that you should continue eating gluten until all testing is completed, including the endoscopy if your doctor orders it.

Darkside Rookie

Thank you and to @trents for the advice. 

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