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Confused on child's labs, want to know what to ask GI


denac

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denac Newbie

Hello! My 5 year old was recently diagnosed by her pediatrician as having celiacs (took her in due to intermittent stomach pain that took place over a few months but ramped up in the last month). He suggested that one of her level's was so high that no further consult with a GI was needed. I did, however, make an appointment with a pediatric GI for next week, but I want to make sure I am informed and that I ask the right questions. My daughters lab results were: 


IGA            47        (33-235 reference)
TTA IGA    <.5       (<= 14.9 Negative)
TTA IGG     .9         (<= 14.9 Negative)
GDA IGA    .3         (<= 14.9 Negative)
GDA IGG   232.8    (<= 14.9 Negative)

Our Pediatric GI appt is in just a few days so I elected not to change her diet at all yet, in case further testing while being exposed to gluten was needed. 
Some questions I already have: Do these results indicate the probability of Celiacs? Does it make sense to request or not request a biopsy? Any other questions that I should ask?

Thank you so much for all of your help, this site and forum has been so informative and helpful at a time when things are very confusing and overwhelming!


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Scott Adams Grand Master

It looks like a high positive on the one test, so it's definitely possible your child has celiac disease. They may want to run more tests, or do a biopsy, so keep them on gluten until you find out.

trents Grand Master

Did the physician not order a tTG-IGA or did you make a typo when you typed TTA-IGA? The tTG-IGA is considered the centerpiece of celiac antibody testing and many physicians will only order that one if they are not willing to order a full panel.

denac Newbie
3 minutes ago, trents said:

Did the physician not order a tTG-IGA or did you make a typo when you typed TTA-IGA? The tTG-IGA is considered the centerpiece of celiac antibody testing and many physicians will only order that one if they are not willing to order a full panel.

That's my mistake - on the report it is listed as: tissue transglutaminase antibody iga. Both of her TTG levels (IGA and IGG) were negative. That's why I am very confused about all of this.

trents Grand Master

I have gotten the impression from participating on this forum for a long time that children sometimes display atypical results in antibody testing. For children under 3 yrs. They aren't reliable at all.

"Blood tests are not always accurate in very young children. If your child is less than 3 years old, you may be advised to see a gastroenterologist instead of relying on blood tests results." https://www.beyondceliac.org/living-with-celiac-disease/info-for-parents/testing/

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