What’s next after Gastroscopy?

[Mica29]

Hi, I was sent for Gastroscopy after 2 blood tests showing an indicator for Coeliac. 
However the results of the biopsy/ Gastroscopy came back as negative. Is it likely that this might be wrong? What normally happens next? 

 

[Scott Adams]

Welcome to the forum. Feel free to share that blood test results with us, and if you do so please also share the reference ranges.

Even just one positive celiac disease blood test result can indicate that you have celiac disease. The biopsy is considered the gold standard to confirm a diagnosis, however if you had two blood test results that were positive it is still likely that you have celiac disease and need to go on a gluten-free diet. At the very least I would say that you may have non-Celiac gluten sensitivity which also requires a gluten-free diet.

[trents]

This happens sometimes. Other forum participants have reported this testing anomaly. Sometimes the damage to the villi in the duodenum is patchy and the biopsies miss the affected areas. This can happen with an inexperienced scoper. Other times the damage is not detectable yet because the disease is caught in very early stages.

Can you share what the specific blood tests that were done, their values and what reference ranges were used by the lab?

[Mica29]

3 minutes ago, Scott Adams said:

Welcome to the forum. Feel free to share that blood test results with us, and if you do so please also share the reference ranges.

Even just one positive celiac disease blood test result can indicate that you have celiac disease. The biopsy is considered the gold standard to confirm a diagnosis, however if you had two blood test results that were positive it is still likely that you have celiac disease and need to go on a gluten-free diet. At the very least I would say that you may have non-Celiac gluten sensitivity which also requires a gluten-free diet.

Thanks, I haven’t got the blood test results but will ask for them and post. It’s really helpful to be able to discuss this with people who have experience with coeliac and am grateful to have found you!

7 minutes ago, trents said:

This happens sometimes. Other forum participants have reported this testing anomaly. Sometimes the damage to the villi in the duodenum is patchy and the biopsies miss the affected areas. This can happen with an inexperienced scoper. Other times the damage is not detectable yet because the disease is caught in very early stages.

Can you share what the specific blood tests that were done, their values and what reference ranges were used by the lab?

Thanks so much, will post if I can get hold of the test results!

[frieze]

3 hours ago, Mica29 said:

Hi, I was sent for Gastroscopy after 2 blood tests showing an indicator for Coeliac. 
However the results of the biopsy/ Gastroscopy came back as negative. Is it likely that this might be wrong? What normally happens next? 

 

A gastroscopy is not the proper test for celiac, hopefully they did an endoscopy, with biopsies 

[trents]

Good catch, frieze. Mica29, can you clarify for us if a gastroscopy (scoping of the stomach) or an endoscopy (scoping of the small bowel which is the part of the digestive track affected by celiac disease)? Both procedures are done from the mouth end but the gastroscopy stops at the stomach.

[Mica29]

8 hours ago, trents said:

Good catch, frieze. Mica29, can you clarify for us if a gastroscopy (scoping of the stomach) or an endoscopy (scoping of the small bowel which is the part of the digestive track affected by celiac disease)? Both procedures are done from the mouth end but the gastroscopy stops at the stomach.

It was described as a Gastroscopy but they took biopsies from small bowel. So technically I suppose it was an endoscopy..