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Celiac?

Scrapmanson
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Scrapmanson Apprentice
Scrapmanson
Posted
  • Author
1 minute ago, trents said:

Nope, doesn't look like celiac disease but if you have celiac-like symptoms you may very well have NCGS (Non Celiac Gluten Sensitivity).

Thanks,  kinda freaked out with what the other stuff says or means in the biopsy,  tried googling but it's pretty confusing. 

 

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trents Grand Master
trents
Posted

Hyperplasia of the Brunner's gland means it is enlarged. These glands reside in the small bowel

"Brunner’s glands are duodenal glands localized predominantly in the submucosa of proximal duodenum. They secrete alkaline fluid composed of mucin (Muc-6) which protects duodenal epithelium by counteracting the acid chime from stomach".

It is possibly working overtime to counteract excess acid in the stomach? Earlier in the thread you describe a problem with burning in your stomach.

Scrapmanson Apprentice
Scrapmanson
Posted
  • Author
38 minutes ago, trents said:

Hyperplasia of the Brunner's gland means it is enlarged. These glands reside in the small bowel

"Brunner’s glands are duodenal glands localized predominantly in the submucosa of proximal duodenum. They secrete alkaline fluid composed of mucin (Muc-6) which protects duodenal epithelium by counteracting the acid chime from stomach".

It is possibly working overtime to counteract excess acid in the stomach? Earlier in the thread you describe a problem with burning in your stomach.

Thank you! Yeah I get burning in abdomen,  bloating,  abdomen pain,  lots of gas,  my tongue is white and sore... But I don't get acid reflux

trents Grand Master
trents
Posted
(edited)
1 hour ago, Scrapmanson said:

Thank you! Yeah I get burning in abdomen,  bloating,  abdomen pain,  lots of gas,  my tongue is white and sore... But I don't get acid reflux

Well, you LES (Lower Esophagial Sphincter) must be sealing the top of the stomach off well and not allowing stomach juices to get up into the esophagus. And there was no mention of a hiatal hernia in the report.

Edited by trents
Courtney541 Rookie
Courtney541
Posted
On 6/27/2022 at 4:27 PM, Scrapmanson said:

Hey guys new here, I've flet horrible and can't seem to get any answers, just trying to see if this is possible celiac or something else. So this long road started about 7yrs ago my daughter got real sick and I started having burning stomach and lost some weight and such, so started going to Dr, for blood work and I got fobed off. Well since then I've had more issues and I'm still only diagnosed with gastritis and ibs. About 3 yrs agoI had CT scan all Clear, colonoscopy all clear, endoscopy with biospy showed mild chronic gastritis, blood work always good except slightly high mpv 11.7 with 11.6 as the standard. My symptoms include burning stomach, abdomen pain, back pain, bloating, tons of gas, white tongue, large sticky stool, floating stool, constipation, loose stool, I'm sure a few things I'm missing. Anyways had a celiac blood test done recently, and I'm scheduled for another endoscopy in 2 weeks. Here's my test results. I did go in today and ask for a total iga serum test, waiting on results. Thanks! 

Ttg iga neg .5<15

Ttg igg neg .8<15

Diam igg neg .4<15

Diam iga pos 22.5

I just got my results too and I’m so confused because my Ttg iga was “positive” at 4 because the reference used was weak positive 4-10 

Scrapmanson Apprentice
Scrapmanson
Posted
  • Author

Well had my appointment yesterday,  Dr said everything is normal..... Like how is that even possible! Now he's thinking either sibo or pancreatic enzyme issues

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    1. knitty kitty
      - knitty kitty replied to Hmart's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
      13

      Is this celiac?

      @Hmart, The reason why your intestinal damage was so severe, yet your tTg IgA was so minimal can be due to cutting back on gluten (and food in general) due to worsening symptoms. The tTg IgA antibodies are made in the intestines. While three grams of gluten per day for several weeks are enough to cause gastrointestinal symptoms, ten grams of gluten...
    2. Trish G
      - Trish G replied to Trish G's topic in Gluten-Free Foods, Products, Shopping & Medications
      10

      Fiber Supplement

      Thanks, that's a great addition that I hadn't thought of.
    3. trents
      - trents replied to Hmart's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
      13

      Is this celiac?

      Other diseases, medical conditions, medications and even (for some people) some non-gluten foods can cause villous atrophy. There is also something called refractory celiac disease but it is pretty uncommon.
    4. trents
      - trents replied to kpf's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
      15

      ttg iga high (646 mg/dl) other results are normal

      knitty kitty asks a very relevant question. So many people make the mistake of experimenting with the gluten free diet or even a reduced gluten diet soon before getting formally tested.
    5. trents
      - trents replied to Trish G's topic in Gluten-Free Foods, Products, Shopping & Medications
      10

      Fiber Supplement

      Another great fiber option is dried apricots. Four of them give you 3g of fiber and I find they don't produce all the gas that some other high fiber options do. They taste good too. Costco sells a large bag of them that are labeled gluten-free so you don't have to worry about cross contamination issues like you might in bulk grocery settings.
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    • knitty kitty
      Is this celiac?

      By knitty kitty · Posted

      @Hmart, The reason why your intestinal damage was so severe, yet your tTg IgA was so minimal can be due to cutting back on gluten (and food in general) due to worsening symptoms.  The tTg IgA antibodies are made in the intestines.  While three grams of gluten per day for several weeks are enough to cause gastrointestinal symptoms, ten grams of gluten per day for for several weeks are required to provoke sufficient antibody production so that the antibodies move out of the intestines and into the blood stream where they can be measured in blood tests.  Since you reduced your gluten consumption before testing, the antibody production went down and did not leave the intestines, hence lower than expected tTg IgA.   Still having abdominal pain and other symptoms this far out is indicative of nutritional deficiencies.  With such a severely damaged small intestine, you are not absorbing sufficient nutrients, especially Thiamine Vitamin B 1, so your body us burning stored fat and even breaking down muscle to fuel your body.   Yes, it is a very good idea to supplement with vitamins and minerals during healing.  The eight essential B vitamins are water soluble and easily lost with diarrhea.  The B vitamins all work together interconnectedly, and should be supplemented together.  Taking vitamin supplements provides your body with greater opportunity to absorb them.  Thiamine and the other B vitamins cannot be stored for long, so they must be replenished every day.  Thiamine tends to become depleted first which leads to Gastrointestinal Beriberi, a condition that doctors frequently fail to recognize.  Symptoms of Gastrointestinal Beriberi are abdominal pain and nausea, but neuropathy can also occur, as well as body and joint pain, headaches and more.  Heart rhythm disruptions including tachycardia are classic symptoms of thiamine deficiency.  Heart attack patients are routinely administered thiamine now.   Blood tests for vitamins are notoriously inaccurate.  You can have "normal" blood levels, while tissues and organs are depleted.  Such is the case with Gastrointestinal Beriberi, a thiamine deficiency in the digestive tract.  Eating a diet high in carbohydrates, like rice, starches, and sugar, can further deplete thiamine.  The more carbohydrates one eats, the more thiamine is required per calorie to turn carbs into energy.  Burning stored fats require less thiamine, so in times of thiamine shortage, the body burns fat and muscles instead.  Muscle wasting is a classic symptoms of thiamine deficiency.  A high carbohydrate diet may also promote SIBO and/or Candida infection which can also add to symptoms.  Thiamine is required to keep SIBO and Candida in check.   Thiamine works with Pyridoxine B 6, so if Thiamine is low and can't interact with Pyridoxine, the unused B 6 accumulates and shows up as high.   Look into the Autoimmune Protocol diet.  Dr. Sarah Ballantyne is a Celiac herself.  Her book "The Paleo Approach" has been most helpful to me.  Following the AIP diet made a huge improvement in my symptoms.  Between the AIP diet and correcting nutritional deficiencies, I felt much better after a long struggle with not feeling well.   Do talk to your doctor about Gastrointestinal Beriberi.  Share the article linked below. Thiamine, gastrointestinal beriberi and acetylcholine signaling https://pmc.ncbi.nlm.nih.gov/articles/PMC12014454/ Keep us posted on your progress!
    • Trish G
      Fiber Supplement

      By Trish G · Posted

      Thanks, that's a great addition that I hadn't thought of. 
    • trents
      Is this celiac?

      By trents · Posted

      Other diseases, medical conditions, medications and even (for some people) some non-gluten foods can cause villous atrophy. There is also something called refractory celiac disease but it is pretty uncommon.
    • trents
      ttg iga high (646 mg/dl) other results are normal

      By trents · Posted

      knitty kitty asks a very relevant question. So many people make the mistake of experimenting with the gluten free diet or even a reduced gluten diet soon before getting formally tested.
    • trents
      Fiber Supplement

      By trents · Posted

      Another great fiber option is dried apricots. Four of them give you 3g of fiber and I find they don't produce all the gas that some other high fiber options do. They taste good too. Costco sells a large bag of them that are labeled gluten-free so you don't have to worry about cross contamination issues like you might in bulk grocery settings.
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