Diagnosis question

[Nadia Whiffin]

Hi, I had a blood test for anti tissue transglutnase and was told that the normal range was 0-19 but my result was 226 so it was likely I have celiac disease but this couldn’t be confirmed until I have a biopsy so I’ve been referred to a gastroenterologist. How likely am I to have celiac just from the blood test? 

[trents]

2 minutes ago, Nadia Whiffin said:

Hi, I had a blood test for anti tissue transglutnase and was told that the normal range was 0-19 but my result was 226 so it was likely I have celiac disease but this couldn’t be confirmed until I have a biopsy so I’ve been referred to a gastroenterologist. How likely am I to have celiac just from the blood test? 

I would say the probability of you having celiac disease is close to 100%. In fact, it is common practice in the UK, if the tTG-IGA values are 10x normal range, for an official celiac diagnosis to be made without ordering an endoscopy/biopsy. So, if you lived in the UK you likely would not have to go in for that additional procedure in order to confirm.

[cristiana]

Hi there Nadia

I agree with Trents, I am quite sure it must be coeliac disease.

Just to say, although Trents is quite right about an endoscopy now not always being thought of as necessary here anymore, I think this change in direction coincided with the pandemic when the gastroenterology departments were struggling with a huge endoscopy backlog.   I am sensing that as this is being cleared, people are being invited to have endoscopies again.  

I would be most interested to learn what your doctor says.  Perhaps you can update us?

All good wishes

Cristiana (British!)