Jump to content

  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.



  • Celiac.com Sponsor (A1):

    Celiac.com Sponsor (A1-M):

  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

Mild atrophy mucosa???

musicalmummy
 Share

Recommended Posts

musicalmummy Apprentice
musicalmummy
Posted

My 15 year old daughters gastroscopy was done today due to having a positive with her blood test for coeliacs. The said what he saw didn’t look too bad for what the naked eye could see. The report he gave us for the gastroscopy states oesophagis normal, stomach normal, and mildly atrophic mucosa was found in the duodenal bulb. 
Will get the biopsy results next week so 🤞🏻 it’s also all normal.

Im beside myself waiting because of it’s not coeliac then they need to do further investigation as to why her bloods were positive.

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


knitty kitty Grand Master
knitty kitty
Posted

Welcome to the forum, @musicalmummy!

Gastroscopy and biopsy is the "Gold Standard" of diagnosis.  

"...mildly atrophic mucosa was found in the duodenal bulb..." may well be Celiac Disease. 

The duodenal bulb is often the area where damage is found.  That's where your doctor can see changes with the naked eye.  Much of the damage in early Celiac Disease is microscopic.  

Not diagnostic.  Not a doctor.  But typical of Celiac.

Some doctors will diagnose Celiac if blood tests are high enough.

Remember Celiac Disease is genetic.  Other family members need to be tested even if they don't have gastrointestinal symptoms.

Keep us posted on the results!

trents Grand Master
trents
Posted
(edited)
1 hour ago, musicalmummy said:

" . . .mildly atrophic mucosa was found in the duodenal bulb . . . "

Im beside myself waiting because of it’s not coeliac then they need to do further investigation as to why her bloods were positive.

 

Atrophy of the duodenal bulb mucosa, especially if it is visible to the naked eye, points to celiac disease.

I guess I'm having a hard time understanding why you hope the biopsy results come back normal. If there is damage to the villi in the small bowel then that would confirm celiac disease and you would have your answer as to what is causing your daughter's health issues. If it comes back negative, you will be in limbo, with two factors indicating having celiac disease and one not.

Edited by trents
musicalmummy Apprentice
musicalmummy
Posted
  • Author
1 hour ago, knitty kitty said:

Welcome to the forum, @musicalmummy!

Gastroscopy and biopsy is the "Gold Standard" of diagnosis.  

"...mildly atrophic mucosa was found in the duodenal bulb..." may well be Celiac Disease. 

The duodenal bulb is often the area where damage is found.  That's where your doctor can see changes with the naked eye.  Much of the damage in early Celiac Disease is microscopic.  

Not diagnostic.  Not a doctor.  But typical of Celiac.

Some doctors will diagnose Celiac if blood tests are high enough.

Remember Celiac Disease is genetic.  Other family members need to be tested even if they don't have gastrointestinal symptoms.

Keep us posted on the results!

Thanks. It’s only been recent that she was sick, since she’d had covid actually about 4 months ago. 
I have had the blood test just after we got her blood results and mine are negative which surprised me as I can’t eat much without feeling gassy and my iron is so low I’m classed anaemic. Once we get biopsy results I’ll check the rest of the family 

52 minutes ago, trents said:

 

Atrophy of the duodenal bulb mucosa, especially if it is visible to the naked eye, points to celiac disease.

I guess I'm having a hard time understanding why you hope the biopsy results come back normal. If there is damage to the villi in the small bowel then that would confirm celiac disease and you would have your answer as to what is causing your daughter's health issues. If it comes back negative, you will be in limbo, with two factors indicating having celiac disease and one not.

Yes I did rethink about this and would prefer the answer we are testing for rather than having to investigate other reasons her bloods were like this 

knitty kitty Grand Master
knitty kitty
Posted
(edited)

@musicalmummy,

You said "I can’t eat much without feeling gassy".  That's  symptomatic of Celiac and you've adjusted your diet not to include "much" already.  

Your body won't make antibodies to gluten if you are not eating gluten.  The blood tests for Celiac measure these antibodies.  Not consuming enough gluten will skew the test to a false negative.

If you were not eating at least two slices of wheat bread (or equivalent) in the two months prior to your antibody tests, you might have a false negative. 

Anemia can affect antibody production and result in a false negative.   So can diabetes.  Anemia impacts production of red blood cells and white blood cells such as the antibody producing cells.  

You might want get genetic testing to see if you carry any of the most common Celiac genes.    

 

Edited by knitty kitty
musicalmummy Apprentice
musicalmummy
Posted
  • Author
2 minutes ago, knitty kitty said:

@musicalmummy,

If you were not eating at least two slices of wheat bread (or equivalent) in the two months prior to your antibody tests, you might have a false negative.   

Your body won't make antibodies to gluten if you are not eating gluten.  The blood tests for Celiac measure these antibodies.  Not consuming enough gluten will skew the test to a false negative.

Anemia can affect antibody production and result in a false negative.   So can diabetes.  Anemia impacts production of red blood cells and white blood cells like antibody producing cells.  

You might want get genetic testing to see if you carry any of the most common Celiac genes.  

 

Yep was eating all gluten so maybe I’m just intolerant. 
I’ll see how her results go and then go further 🙂

musicalmummy Apprentice
musicalmummy
Posted
  • Author

The gastrologist rang and has put my daughter on an emergency wait list to discuss her results 

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


knitty kitty Grand Master
knitty kitty
Posted

@musicalmummy

We're praying for you all.

trents Grand Master
trents
Posted
(edited)
6 hours ago, musicalmummy said:

The gastrologist rang and has put my daughter on an emergency wait list to discuss her results 

An emergency wait list? That sounds like a contradiction in terms. What kind of symptoms is your daughter having? Is she quite ill?

Edited by trents
musicalmummy Apprentice
musicalmummy
Posted
  • Author
On 10/22/2022 at 12:47 AM, trents said:

An emergency wait list? That sounds like a contradiction in terms. What kind of symptoms is your daughter having? Is she quite ill?

I meant emergency cancellation. 
She feels ill and nauseous after eating

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!

Register a new account

Sign in

Already have an account? Sign in here.

Sign In Now
 Share
Go to topic listing

  • Get Celiac.com Updates:
    Support Celiac.com:
    Join eNewsletter
    Donate
  • Celiac.com Sponsor (A17):
    Celiac.com Sponsor (A17):



    Celiac.com Sponsors (A17-M):



  • Recent Activity

    1. trents
      - trents replied to catnapt's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
      5

      how much gluten do I need to eat before blood tests?

      The rate of damage to the villous lining of the SB and the corresponding loss of nutrient absorbing efficiency varies tremendously from celiac to celiac. Yes, probably is dose dependent if, by dose dependent you mean the amount of exposure to gluten. But damage rates and level of sensitivity also seem to depend on the genetic profile. Those with both genes...
    2. MauraBue
      - MauraBue posted a topic in Gluten-Free Foods, Products, Shopping & Medications
      0

      Have Tru Joy Sweets Choco Chews been discontinued??

      Help! My 5 year old daughter just stopped eating dairy and gluten due to her EoE and Celiac. Her favorite candy in the world is tootsie rolls. I did some research, and it sounds like these are the only options for finding something similar, but I can't find them anywhere to actually purchase. Have they been discontinued?? Does anyone have another recommendation...
    3. catnapt
      - catnapt replied to catnapt's topic in Celiac Disease Pre-Diagnosis, Testing & Symptoms
      5

      how much gluten do I need to eat before blood tests?

      I wonder how long it usually takes and if it is dose dependent as well... or if some ppl have a more pronounced reaction to gluten than others thanks again for all the great info
    4. suek54
      - suek54 replied to suek54's topic in Dermatitis Herpetiformis
      7

      Awaiting dermatitis herpetiformis confirmation following biopsy

      Wow KK, thank you so much for all your attached info. I had a very quick scan but will read more in depth later. The one concerning corticosteroid use is very interesting. That would relate to secondary adrenal insufficiency I think , ie AI caused by steroids such as taken long term for eg asthma. I have primary autoimmune AI, my adrenals are atrophied...
    5. knitty kitty
      - knitty kitty replied to suek54's topic in Dermatitis Herpetiformis
      7

      Awaiting dermatitis herpetiformis confirmation following biopsy

      Welcome to the forum, @suek54, I have Dermatitis Herpetiformis, too. I found taking Niacin B3 very helpful in clearing my skin from blisters as well as improving the itchies-without-rash (peripheral neuropathy). Niacin has been used since the 1950's to improve dermatitis herpetiformis. I try to balance my iodine intake (which will cause flairs...
  • Celiac.com Sponsor (A19):

  • Member Statistics

    • Total Members
      133,260
    • Most Online (within 30 mins)
      7,748
    MauraBue
    Newest Member
    MauraBue
    Joined
  • Celiac.com Sponsor (A20):
  • Celiac.com Sponsor (A22):

  • Forum Statistics

    • Total Topics
      121.6k
    • Total Posts
      1m
  • Celiac.com Sponsor (A21):

  • Upcoming Events

  • Posts

    • trents
      how much gluten do I need to eat before blood tests?

      By trents · Posted

      The rate of damage to the villous lining of the SB and the corresponding loss of nutrient absorbing efficiency varies tremendously from celiac to celiac. Yes, probably is dose dependent if, by dose dependent you mean the amount of exposure to gluten. But damage rates and level of sensitivity also seem to depend on the genetic profile. Those with both genes HLA-DQ2 and HLA-DQ8 seem to be more sensitive to minor amounts of gluten exposure than those with just one of those genes and those with only DQ2 seem to be more sensitive than those with only DQ8. But there are probably many factors that influence the damage rate to the villi as well as intensity of reaction to exposure. There is still a lot we don't know. One of the gray areas is in regard to those who are "silent" celiacs, i.e. those who seem to be asymptomatic or whose symptoms are so minor that they don't garner attention. When they get a small exposure (such as happens in cross contamination) and have no symptoms does that equate to no inflammation? We don't necessarily know. The "sensitive" celiac knows without a doubt, however, when they get exposure from cross contamination and the helps them know better what food products to avoid.
    • MauraBue
      Have Tru Joy Sweets Choco Chews been discontinued??

      By MauraBue · Posted

      Help!  My 5 year old daughter just stopped eating dairy and gluten due to her EoE and Celiac.  Her favorite candy in the world is tootsie rolls.  I did some research, and it sounds like these are the only options for finding something similar, but I can't find them anywhere to actually purchase.  Have they been discontinued??  Does anyone have another recommendation for a gluten-free/DF tootsie roll option?
    • catnapt
      how much gluten do I need to eat before blood tests?

      By catnapt · Posted

      I wonder how long it usually takes and if it is dose dependent as well... or if some ppl have a more pronounced reaction to gluten than others   thanks again for all the great info    
    • suek54
      Awaiting dermatitis herpetiformis confirmation following biopsy

      By suek54 · Posted

      Wow KK, thank you so much for all your attached info. I had a very quick scan but will read more in depth later.  The one concerning corticosteroid use is very interesting. That would relate to secondary adrenal insufficiency I think , ie AI caused by steroids such as taken long term for eg asthma. I have primary autoimmune AI, my adrenals are atrophied, no chance if recovery there. But I am in touch with some secondaries, so something to bear in mind. .  Niacin B3 Very interesting too. Must have a good read about that.  Im sure lots of questions will arise as I progress with dermatitis herpetiformis. In the mean time, thanks for your help.
    • knitty kitty
      Awaiting dermatitis herpetiformis confirmation following biopsy

      By knitty kitty · Posted

      Welcome to the forum, @suek54, I have Dermatitis Herpetiformis, too.  I found taking Niacin B3 very helpful in clearing my skin from blisters as well as improving the itchies-without-rash (peripheral neuropathy).  Niacin has been used since the 1950's to improve dermatitis herpetiformis.   I try to balance my iodine intake (which will cause flairs) with Selenium which improves thyroid function.   Interesting Reading: Dermatitis herpetiformis effectively treated with heparin, tetracycline and nicotinamide https://pubmed.ncbi.nlm.nih.gov/10844495/   Experience with selenium used to recover adrenocortical function in patients taking glucocorticosteroids long https://pubmed.ncbi.nlm.nih.gov/24437222/   Two Cases of Dermatitis Herpetiformis Successfully Treated with Tetracycline and Niacinamide https://pubmed.ncbi.nlm.nih.gov/30390734/   Steroid-Resistant Rash With Neuropsychiatric Deterioration and Weight Loss: A Modern-Day Case of Pellagra https://pmc.ncbi.nlm.nih.gov/articles/PMC12532421/#:~:text=Figure 2.,(right panel) upper limbs.&text=The distribution of the rash,patient's substantial response to treatment.   Nicotinic acid therapy of dermatitis herpetiformis (1950) https://pubmed.ncbi.nlm.nih.gov/15412276/
×
×
  • Create New...

Important Information

NOTICE: This site places This site places cookies on your device (Cookie settings). on your device. Continued use is acceptance of our Terms of Use, and Privacy Policy.