Jump to content

  • Welcome to Celiac.com!

    You have found your celiac tribe! Join us and ask questions in our forum, share your story, and connect with others.


  • Celiac.com Sponsor (A1):
    Celiac.com Sponsor (A1-M):

  • Get Celiac.com Updates:
    Support Our Content
    eNewsletter
    Donate

TTG 25

LP023
 Share

Recommended Posts

LP023 Contributor
LP023
Posted

I recently had a ttg and the results were 25 and I was told that it was positive by Gastro. I don’t hurt when I eat gluten but I feel awful when I eat vegetables and meat like on a keto diet. Could it be false positive? Is 25 high enough to be a for sure diagnoses? I can go several months with no issues at all and then get sick but eating bread, pasta, pizza and other foods that contain gluten don’t bother me.

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


trents Grand Master
trents
Posted

Welcome to the forum, LP023!

Can you also supply the reference range for negative vs. positive? Without that it is not possible to say whether or not your score represents a strong positive as each lab uses a different standard.

Yes, it is possible that this represents a false positive but not likely. The tTG-IGA is considered to a celiac test with good specificity and good sensitivity. The next logical step is for you to schedule an endoscopy with biopsy of the small bowel lining. That is considered to be the gold standard test for celiac disease.

The fact that you do not experience GI distress when you consume gluten products certainly does not rule out celiac disease. A high percentage of those with active celiac disease do not have GI distress, at least not until the damage to the small bowel villi gets to an advanced stage. We call them "silent celiacs". The fact that you have trouble digesting meat and veggies could very well be caused by a damaged gut from celiac disease.

If you intend to go for the endoscopy/biopsy, make sure you do not start a gluten free diet until that is done.

Scott Adams Grand Master
Scott Adams
Posted

Did they also run any other celiac disease tests in your panel, for example DPG?

LP023 Contributor
LP023
Posted
  • Author
15 hours ago, trents said:

Welcome to the forum, LP023!

Can you also supply the reference range for negative vs. positive? Without that it is not possible to say whether or not your score represents a strong positive as each lab uses a different standard.

Yes, it is possible that this represents a false positive but not likely. The tTG-IGA is considered to a celiac test with good specificity and good sensitivity. The next logical step is for you to schedule an endoscopy with biopsy of the small bowel lining. That is considered to be the gold standard test for celiac disease.

The fact that you do not experience GI distress when you consume gluten products certainly does not rule out celiac disease. A high percentage of those with active celiac disease do not have GI distress, at least not until the damage to the small bowel villi gets to an advanced stage. We call them "silent celiacs". The fact that you have trouble digesting meat and veggies could very well be caused by a damaged gut from celiac disease.

If you intend to go for the endoscopy/biopsy, make sure you do not start a gluten free diet until that is done.

I think 0-3 negative

4-10 week positive and anything over 10 positive. 

LP023 Contributor
LP023
Posted
  • Author
2 hours ago, Scott Adams said:

Did they also run any other celiac disease tests in your panel, for example DPG?

Not that I know of. CRP was fine. I guess that’s for inflammation.  Vitamins were fine. Running a colonoscopy, swallow test and upper endo but the wait is long. I haven’t eaten gluten in 4 days. Ate a salad with no dressing and pain started. Mine seems to be vegetables and fruit. Sometimes meat. Makes no sense to me. 

trents Grand Master
trents
Posted

If you eliminate or cut back on gluten before all testing is complete you will undermine the results. Since you say gluten doesn't bother you, you should be able to weather that period without undue suffering. Can you do dairy and eggs without discomfort so as to meet protein needs?

LP023 Contributor
LP023
Posted
  • Author

Eggs is a no. Dairy sometimes. It’s looking like 2 months before the tests will be done. I thought I would try it for awhile to see what happened if I cut out gluten for a week. I’ve read that the blood test was 98% accurate. 25 is 15 over the positive limit but I’ve seen where some people were in the 100s. I had Covid a year ago and since then I’ve felt hungry non stop and stomach noises are constant. Most days I feel good. Just some really bad weeks scattered in. 

Celiac.com Sponsor (A8):
Celiac.com Sponsor (A8):

Celiac.com Sponsor (A8-M):


trents Grand Master
trents
Posted

If you eliminate or cut back on gluten before all testing is complete you will undermine the results. Since you say gluten doesn't bother you, you should be able to weather that period without undue suffering. Can you do dairy and eggs without discomfort so as to meet protein needs?

The Mayo Clinic Guidelines for the pretest gluten challenge leading up to the endoscopy/biopsy is the daily consumption of two slices of wheat bread (or the gluten equivalent) for two weeks prior. That should help you in your planning.

  • 2 weeks later...
Raptorsgal Enthusiast
Raptorsgal
Posted

Mine ttg. was 80 a lot higher . I also stop gluten it’s been a few days seem to be helping gluten in everything 

Scott Adams Grand Master
Scott Adams
Posted

As @trents mentioned, be sure not to eliminate gluten until all tests for celiac disease have been completed.

Raptorsgal Enthusiast
Raptorsgal
Posted

The doctor pretty sure I had it there’d been no test scheduled if they are it could be months and months .

oat milk and granola are they l always gluten free so confusing 

trents Grand Master
trents
Posted
2 minutes ago, Raptorsgal said:

oat milk and granola are they l always gluten free so confusing 

Oats and granola are not necessarily gluten free because of the likelihood of cross contamination with wheat in the field, in transport, in storage and in processing. Milk is gluten free.

Raptorsgal Enthusiast
Raptorsgal
Posted

It’s so hard I needed to eat something hopeful things get better waiting for a library book

  • 2 weeks later...
RecoveredCeliac Apprentice
RecoveredCeliac
Posted
On 1/26/2023 at 2:12 PM, LP023 said:

25 is 15 over the positive limit 

doesn't matter if other people were hundreds over normal range

ttg iga?    ttg iga is over 99% accurate for celiac

If you have 15 above normal ttg iga then you are definitely positive

 

LP023 Contributor
LP023
Posted
  • Author
51 minutes ago, RecoveredCeliac said:

doesn't matter if other people were hundreds over normal range

ttg iga?    ttg iga is over 99% accurate for celiac

If you have 15 above normal ttg iga then you are definitely positive

 

Most likely am positive but I know when I worked in the lab several years ago I learned really quick false positives for several things aren’t as uncommon as we think. Other autoimmune diseases can cause false positives. HIV antibody testing is a huge false positive risk and they say it’s 99% accurate. Every time we had a positive it was sent off for confirmation testing to make sure it was really positive. As far as I know there isn’t another blood test to confirm celiacs if one comes back positive but it’s been awhile since I worked in that field. 

trents Grand Master
trents
Posted
3 hours ago, LP023 said:

Most likely am positive but I know when I worked in the lab several years ago I learned really quick false positives for several things aren’t as uncommon as we think. Other autoimmune diseases can cause false positives. HIV antibody testing is a huge false positive risk and they say it’s 99% accurate. Every time we had a positive it was sent off for confirmation testing to make sure it was really positive. As far as I know there isn’t another blood test to confirm celiacs if one comes back positive but it’s been awhile since I worked in that field. 

There are a number of celiac antibody tests that can be ordered. The most popular one with PC physicians is the tTG-IGA, and it may be the best all around test for celiac disease but full panel is always better.

https://celiac.org/about-celiac-disease/screening-and-diagnosis/screening/

LP023 Contributor
LP023
Posted
  • Author

A67EA4BA-5F13-40D1-A107-B08FC164D101.png.8e68f67083560949b842fe161a4a8459.png/

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!

Register a new account

Sign in

Already have an account? Sign in here.

Sign In Now
 Share
Go to topic listing
  • Celiac.com Sponsor (A19):

  • Member Statistics

    • Total Members
      133,428
    • Most Online (within 30 mins)
      7,748
    twin68grcom
    Newest Member
    twin68grcom
    Joined
  • Celiac.com Sponsor (A20):
  • Celiac.com Sponsor (A22):

  • Forum Statistics

    • Total Topics
      121.6k
    • Total Posts
      1m
  • Celiac.com Sponsor (A21):

  • Upcoming Events

  • Posts

    • catnapt
      results from 13 day gluten challenge - does this mean I can't have celiac?

      By catnapt · Posted

      just a few days off of that drug and my digestive system is finally getting back to normal stopping the gluten challenge was not enough to get back to normal, I was still horribly constipated with what seemed like a paralyzed digestive track- nothing was moving! but now, with a few mag citrate capsules that I had to order online and stopping the chlorthalidone, things are getting back to my usual "working well" digestion   so it's clear that the symptoms I had during the gluten challenge were compounded by the new med that was started the same day (I feel like the Dr really should have known better than to do those two things at the same time, add a new drug and start a new diet protocol... but I'm just the patient, what do I  know, right?)   I am going to do another 24 hr urine in a few weeks to see if lowering the dose of vit D gets my urine calcium down to a more tolerable level. that's the plan.  hope it works.  
    • Wheatwacked
      results from 13 day gluten challenge - does this mean I can't have celiac?

      By Wheatwacked · Posted

      Keep it up.  
    • catnapt
      results from 13 day gluten challenge - does this mean I can't have celiac?

      By catnapt · Posted

      oh geez!! i made a whole long detailed post and it didn't save it   I give up grrrrrrrrrrr  
    • catnapt
      results from 13 day gluten challenge - does this mean I can't have celiac?

      By catnapt · Posted

      I'm not delaying my recovery- I was well on my way to recovering, IF I do have celiac disease by listening to my body and not eating the foods that made me feel ill. the drug I just stopped taking was making me incredibly ill and it's unfortunate and more than  a little frustrating that the dr  
    • Wheatwacked
      results from 13 day gluten challenge - does this mean I can't have celiac?

      By Wheatwacked · Posted

      Click on the image to make it larger.  Maybe doesn't work on phone browser,  That was from 2021. Absolutely, they should be tested, The point is you have symptoms that the doctors don't understand and malabsorption may be the cause.   Not trying to.  But much of your rant includes refeferences that may indicate multiple nutritional deficiencies.     Some countries also have tax incentives and financial aid for Celiacs.   Celiac disease is recognized as a disability under the ADA because it substantially limits major life activities like eating and digestive function. Protections require reasonable accommodations in public accommodations, including schools (504 plans), colleges, and hospitals. These often include providing safe, gluten-free food, though they do not force restaurants to provide it.  As far as your recovery, eat gluten free.  Get healthier now and worry about diagnosis later.  Many here on the forum have gone ten or more years looking for a diagnosis, with many doctors and many misdiagnosis along the way. It really doesn't matter why, but you cannot eat  gluten.  That is what is important.  With gluten out of the way, maybe the doctors can make sense of your remaining symptoms.  If you need the ADA, then a medical diagnosis is the way to go.  Meantime you are delaying your recovery from whichever celiac disease or NCGS and the inevitable step one of Gluten Free Diet. tWe come to share experiences and maybe it will help someone. In reality, I don't care.  By the way I have stopped 6 medications Against Medical Advice because they did not do their job and the side effects were crippling. This is a lifelong fight for your life.  Pick you battles carefully.  Assume the worst, celiac disease, and deal with it.  Denial is not just a river in Egypt. Pleased to meet you, too.  
×
×
  • Create New...

Important Information

NOTICE: This site places This site places cookies on your device (Cookie settings). on your device. Continued use is acceptance of our Terms of Use, and Privacy Policy.