False negative blood test in children

[Mathew]

I have celiacs desease, so did my dad. I had my daughters tested in aug 2022 and my oldest was positive and my yougest negative. Now my youngest is 11 and has been suffering from vacant episodes, dizziness, dream state. She has gluten in her diet. She has been tested for epilepsy and that was negative. She has had a heart tracer (waiting results) and an MRI scan on Friday. 

 

My question is, could the test be afalse negative? And could these symptoms be Ataxia?

[ravenwoodglass]

Just because her result was negative before does not mean it will be now. Do get her retested with a full panel.  It sounds like she may have more neuro impact than GI so her blood work may still be false negative. The antibodies can cause something called UBOs on a brain MRI which are similiear to the lesions founds with MS but in different places. Do keep her on gluten till all testing is done.  I hope things get better for all of you soon. It is so hard when your children are ill.

[Mathew]

  On 3/22/2023 at 3:20 PM, ravenwoodglass said:

Just because her result was negative before does not mean it will be now. Do get her retested with a full panel.  It sounds like she may have more neuro impact than GI so her blood work may still be false negative. The antibodies can cause something called UBOs on a brain MRI which are similiear to the lesions founds with MS but in different places. Do keep her on gluten till all testing is done.  I hope things get better for all of you soon. It is so hard when your children are ill.

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She was having the episodes at the time she was tested in Aug 2022. But i hear what ya saying. Would a brain MRI show this that ya talking about?

[Scott Adams]

It would be best to ask your doctor about this, but @ravenwoodglass definitely knows a lot about such things, so it is likely that an MRI would reveal gluten-related brain issues, including calcifications in certain areas, which have been associated with celiac disease.