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Hidden Sources of Gluten?


ac5858

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ac5858 Newbie

I have been gluten-free for 12 years now and of course deal with the occasional flare-ups of getting "glutened." I recently went on an SSRI (Zoloft/Sertaline), and have been experiencing the strangest symptoms, and can't help but wonder if they are due to gluten. I have been extremely fatigued, horrible headaches, canker sores that will not go away, acne, and brain fog. 

Has anyone else experienced something similar? 


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trents Grand Master

How long have you been taking the SSRI? Maybe it's a matter of your body needing more time to adjust to it or maybe the dosage needs to be adjusted.

Also, as you know, wheat starch can be used in pills as a filler. See what you can find out from the dispensing pharmacy and if necessary they can give you information about their supplier to ask more detailed questions.

Many medications also leach or block the uptake of certain nutrients and that could figure into your symptoms.

There is also the possibility that you have developed an additional food intolerance that mimics the effect of gluten. Do you have celiac disease or NCGS (Non Celiac Gluten Sensitivity)?

knitty kitty Grand Master

@ac5858,

After being on the gluten free diet for such a long time, it is more likely you have developed nutritional deficiencies.

1 hour ago, ac5858 said:

 I have been extremely fatigued, horrible headaches, canker sores that will not go away, acne, and brain fog. 

These are all symptoms of Thiamine deficiency.  I know from experience, thiamine deficiency will cause Depression, extreme fatigue, headaches and brain fog, and canker sores and acne.

Nutritional deficiencies can occur on the gluten free diet.  Processed gluten free facsimile foods are not enriched with vitamins and minerals lost in processing like gluten based foods are required by law to do.  

Thiamine is Vitamin B 1.  Thiamine works with magnesium (magnesium glycinate is the gentleman form) and the other seven B vitamins.  Thiamine can only be stored for three weeks, with deficiency symptoms occurring within a week.  One can have a subclinical thiamine deficiency for a long time.  Symptoms can wax and wane depending on how much Thiamine is included in the diet daily.  

Vitamin D deficiency is also a cause of depression.

My depression did NOT resolve on antidepressants.  Only after supplementing with Vitamin D (my lab test showed severe Vitamin D deficiency) and Thiamine.  

Here are some articles that explain more in depth....

 

For those canker sores...

Recurrent aphthous stomatitis and thiamine deficiency

https://pubmed.ncbi.nlm.nih.gov/8974135/

AND...

Recurrent aphthous ulceration: vitamin B1, B2 and B6 status and response to replacement therapy

https://pubmed.ncbi.nlm.nih.gov/1941656/

 

DEPRESSION....

Adjuvant thiamine improved standard treatment in patients with major depressive disorder: results from a randomized, double-blind, and placebo-controlled clinical trial

https://pubmed.ncbi.nlm.nih.gov/26984349/

AND...

Neurological, Psychiatric, and Biochemical Aspects of Thiamine Deficiency in Children and Adults

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6459027/?report=reader

 

Vitamin D and depression

Vitamin D and Depression: A Critical Appraisal of the Evidence and Future Directions

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6970300/

 

DIET...

Antidepressant foods: An evidence-based nutrient profiling system for depression

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147775/?report=reader

 

 

Do get checked for vitamin and mineral deficiencies!  Discuss with your doctor the benefits of supplementing with extra thiamine and a B Complex, and Vitamin D, and magnesium.

Hope this helps!

plumbago Experienced

I've gotten aptheous (spelling?) ulcers in my mouth - but it's been a while. It may have been due to tomatoes, sugar, or something viral. I was never really able to nail it down for sure. I did change to a toothpaste without SLS. For the most part, everything I did (new toothpaste, trying hard not always successfully to reduce sugar)

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    • Scott Adams
      If your tTg-IgA was 28 and positive is at 3, you are nearly 10x over the positive marker, so the most likely explanation by far would be celiac disease. I also do not understand why your doctor would not want to run the blood test, which is the normal first step in the diagnosis process.
    • xxnonamexx
      Is there a digestive enzyme that helps build a healthier gut? I see people taking them but not sure what really works
    • trents
      So the tTG-IGA at 28 is positive for celiac disease. There are some other medical conditions that can cause elevated tTG-IGA but this is unlikely. There are some people for whom the dairy protein casein can cause this but by far the most likely cause is celiac disease. Especially when your small bowel lining is "scalloped". Your Serum IGA 01 (aka, "total IGA") at 245 mg/dl is within normal range, indicating you are not IGA deficient. But I also think it would be wise to take your doctor's advice about the sucraid diet and avoiding dairy . . . at least until you experience healing and your gut has had a chance to heal, which can take around two years. After that, you can experiment with adding dairy back in and monitor symptoms. By the way, if you want the protein afforded by dairy but need to avoid casein, you can do so with whey protein powder. Whey is the other major protein in dairy.
    • jenniber
      hi, i want to say thank you to you and @trents   . after 2 phone calls to my GI, her office called me back to tell me that a blood test was “unnecessary” and that we should “follow the gold standard” and since my biopsy did not indicate celiac, to follow the no dairy and sucraid diet. i luckily have expendable income and made an appt for the labcorp blood test that day. i just got my results back and it indicates celiac disease i think 😭   im honestly happy bc now i KNOW and i can go gluten free. and i am SO MAD at this doctor for dismissing me for a simple blood test that wouldn’t have cost her anything !!!!!!!!!!! im sorry, im so emotional right now, i have been sick my whole life and never knew why, i feel so much better already   my results from labcorp:   Celiac Ab tTG TIgA w/Rflx Test Current Result and Flag Previous Result and Date Units Reference Interval t-Transglutaminase (tTG) IgA 01 28 High U/mL 0-3 Negative 0 - 3 Weak Positive 4 - 10 Positive >10 Tissue Transglutaminase (tTG) has been identified as the endomysial antigen. Studies have demonstrated that endomysial IgA antibodies have over 99% specificity for gluten sensitive enteropathy. Immunoglobulin A, Qn, Serum 01 245 mg/dL 87-352
    • JoJo0611
      Thank you this really helped. 
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