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Hidden Sources of Gluten?


ac5858

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ac5858 Newbie

I have been gluten-free for 12 years now and of course deal with the occasional flare-ups of getting "glutened." I recently went on an SSRI (Zoloft/Sertaline), and have been experiencing the strangest symptoms, and can't help but wonder if they are due to gluten. I have been extremely fatigued, horrible headaches, canker sores that will not go away, acne, and brain fog. 

Has anyone else experienced something similar? 


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trents Grand Master

How long have you been taking the SSRI? Maybe it's a matter of your body needing more time to adjust to it or maybe the dosage needs to be adjusted.

Also, as you know, wheat starch can be used in pills as a filler. See what you can find out from the dispensing pharmacy and if necessary they can give you information about their supplier to ask more detailed questions.

Many medications also leach or block the uptake of certain nutrients and that could figure into your symptoms.

There is also the possibility that you have developed an additional food intolerance that mimics the effect of gluten. Do you have celiac disease or NCGS (Non Celiac Gluten Sensitivity)?

knitty kitty Grand Master

@ac5858,

After being on the gluten free diet for such a long time, it is more likely you have developed nutritional deficiencies.

1 hour ago, ac5858 said:

 I have been extremely fatigued, horrible headaches, canker sores that will not go away, acne, and brain fog. 

These are all symptoms of Thiamine deficiency.  I know from experience, thiamine deficiency will cause Depression, extreme fatigue, headaches and brain fog, and canker sores and acne.

Nutritional deficiencies can occur on the gluten free diet.  Processed gluten free facsimile foods are not enriched with vitamins and minerals lost in processing like gluten based foods are required by law to do.  

Thiamine is Vitamin B 1.  Thiamine works with magnesium (magnesium glycinate is the gentleman form) and the other seven B vitamins.  Thiamine can only be stored for three weeks, with deficiency symptoms occurring within a week.  One can have a subclinical thiamine deficiency for a long time.  Symptoms can wax and wane depending on how much Thiamine is included in the diet daily.  

Vitamin D deficiency is also a cause of depression.

My depression did NOT resolve on antidepressants.  Only after supplementing with Vitamin D (my lab test showed severe Vitamin D deficiency) and Thiamine.  

Here are some articles that explain more in depth....

 

For those canker sores...

Recurrent aphthous stomatitis and thiamine deficiency

https://pubmed.ncbi.nlm.nih.gov/8974135/

AND...

Recurrent aphthous ulceration: vitamin B1, B2 and B6 status and response to replacement therapy

https://pubmed.ncbi.nlm.nih.gov/1941656/

 

DEPRESSION....

Adjuvant thiamine improved standard treatment in patients with major depressive disorder: results from a randomized, double-blind, and placebo-controlled clinical trial

https://pubmed.ncbi.nlm.nih.gov/26984349/

AND...

Neurological, Psychiatric, and Biochemical Aspects of Thiamine Deficiency in Children and Adults

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6459027/?report=reader

 

Vitamin D and depression

Vitamin D and Depression: A Critical Appraisal of the Evidence and Future Directions

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6970300/

 

DIET...

Antidepressant foods: An evidence-based nutrient profiling system for depression

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147775/?report=reader

 

 

Do get checked for vitamin and mineral deficiencies!  Discuss with your doctor the benefits of supplementing with extra thiamine and a B Complex, and Vitamin D, and magnesium.

Hope this helps!

plumbago Experienced

I've gotten aptheous (spelling?) ulcers in my mouth - but it's been a while. It may have been due to tomatoes, sugar, or something viral. I was never really able to nail it down for sure. I did change to a toothpaste without SLS. For the most part, everything I did (new toothpaste, trying hard not always successfully to reduce sugar)

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    • knitty kitty
      You're right, doctors usually only test Vitamin D and B12.  Both are really important, but they're not good indicators of deficiencies in the other B vitamins.  Our bodies are able to store Vitamin B12 and Vitamin D in the liver for up to a year or longer.  The other B vitamins can only be stored for much shorter periods of time.  Pyridoxine B 6 can be stored for several months, but the others only a month or two at the longest.  Thiamine stores can be depleted in as little as three days.  There's no correlation between B12 levels and the other B vitamins' levels.  Blood tests can't measure the amount of vitamins stored inside cells where they are used.  There's disagreement as to what optimal vitamin levels are.  The Recommended Daily Allowance is based on the minimum daily amount needed to prevent disease set back in the forties when people ate a totally different diet and gruesome experiments were done on people.  Folate  requirements had to be updated in the nineties after spina bifida increased and synthetic folic acid was mandated to be added to grain products.  Vitamin D requirements have been updated only in the past few years.   Doctors aren't required to take as many hours of nutritional education as in the past.  They're educated in learning institutions funded by pharmaceutical corporations.  Natural substances like vitamins can't be patented, so there's more money to be made prescribing pharmaceuticals than vitamins.   Also, look into the Autoimmune Protocol Diet, developed by Dr. Sarah Ballantyne, a Celiac herself.  Her book The Paleo Approach has been most helpful to me.  You're very welcome.  I'm glad I can help you around some stumbling blocks while on this journey.    Keep me posted on your progress!  Best wishes! P.S.  interesting reading: Thiamine, gastrointestinal beriberi and acetylcholine signaling https://pmc.ncbi.nlm.nih.gov/articles/PMC12014454/
    • NanceK
      So interesting that you stated you had sub clinical vitamin deficiencies. When I was first diagnosed with celiac disease (silent), the vitamin levels my doctor did test for were mostly within normal range (lower end) with the exception of vitamin D. I believe he tested D, B12, magnesium, and iron.  I wondered how it was possible that I had celiac disease without being deficient in everything!  I’m wondering now if I have subclinical vitamin deficiencies as well, because even though I remain gluten free, I struggle with insomnia, low energy, body aches, etc.  It’s truly frustrating when you stay true to the gluten-free diet, yet feel fatigued most days. I’ll definitely try the B-complex, and the Benfotiamine again, and will keep you posted. Thanks once again!
    • knitty kitty
      Segments of the protein Casein are the same as segments of the protein strands of gluten, the 33-mer segment.   The cow's body builds that Casein protein.  It doesn't come from wheat.   Casein can trigger the same reaction as being exposed to gluten in some people.   This is not a dairy allergy (IGE mediated response).  It is not lactose intolerance.  
    • trents
      Wheatwacked, what exactly did you intend when you stated that wheat is incorporated into the milk of cows fed wheat? Obviously, the gluten would be broken down by digestion and is too large a molecule anyway to cross the intestinal membrane and get into the bloodstream of the cow. What is it from the wheat that you are saying becomes incorporated into the milk protein?
    • Scott Adams
      Wheat in cow feed would not equal gluten in the milk, @Wheatwacked, please back up extraordinary claims like this with some scientific backing, as I've never heard that cow's milk could contain gluten due to what the cow eats.
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