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IgA Deficient

BigDogz
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BigDogz Explorer
BigDogz
Posted

Hello, everyone...

I was recently seen by a Rheumatologist due to muscle & joint pain, extreme fatigue, GERD, episodic diarrhea & these crazy rashes that are worsened when in the sun. As part of my testing he ran a total IgA test & it was undetectable according to the lab. He also ran tTG-IgG, Gliadin IgG tests & HLA testing. The Gliadin test was entirely negative (<1.0). The HLA testing showed "HLA-DQB1 0202 & HLA-DQB1 0603, serologic equivalent: HLA-DQ 2,1 (subtype 2,6)". The tTG- IgG was 8.5U/ml. The lab that ran it uses 15U/ml as the level for a positive test so they declared that testing negative, as well. I note that other institutions consider up to 9.0U/ml as "weakly positive". 

1) Based on these results, am I negative or "weakly positive" for Celiac?

2) Do these results indicate that I'm "gluten sensitive/intolerant"?

3) Being completely IgA deficient, will I eventually develop Celiac Disease?

4) Would I benefit and/or prevent further gluten-related issues if I adopt a gluten-free lifestyle?

 

Thanks so much for your knowledge & insights!

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Scott Adams Grand Master
Scott Adams
Posted

To me your blood test results are likely negative, as your doctor indicated, but they may indicate that you have some level of gluten sensitivity, so you may still want to try a gluten-free diet.  Approximately 10x more people have non-celiac gluten sensitivity than have celiac disease, but there isn’t yet a test for NCGS. If your symptoms go away on a gluten-free diet it would likely signal NCGS.

 

 

RMJ Mentor
RMJ
Posted

Were you eating gluten prior to the testing? From your previous posts it looks like you try to be gluten free.

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